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Doctor insights on: Is There Any Teratogenic Cause Of Omphalocele

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Is there any teratogenic cause of omphalocele?

Is there any teratogenic cause of omphalocele?

Unsure: Omphalocele is a failure of the return of the midgut from the yolk sac to the abdomen before 10 weeks of gestation. It can be associated with other malformations and syndromes. Best to ask the neonatologist and/or a geneticist for each individual case. The intestines are involved in 1/5000 births, with liver and intestines occurring in 1/10000 births. Immediate surgical repair is required. ...Read more

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Dr. Stephen Kim
35 doctors shared insights

Omphalocele (Definition)

Omphalocele is a birth defect of the abdominal (belly) wall. The infant’s intestines, liver, or other organs may stick outside of the belly through the belly button. The organs are covered in a thin, nearly transparent sac that hardly ever is open or broken. It is associated with a high rate of mortality and severe malformations, such as cardiac anomalies ...Read more


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What causes omphalocele and is it a highrisk pregnancy?

What causes omphalocele and is it a highrisk pregnancy?

Yes: Yes it is a high risk prenancy and requires good prenatal care. No, we do not know what causes omphalocele although there are several genetic syndromes which are not hereditary and usually discovered post natally such as hemi hypertrophy and or beckwith weidemann. ...Read more

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What causes teratogenesis?

What causes teratogenesis?

Tertatogensis: long list of medications, infections, enviromental agents that can cause problems to the developing embryo. The general rule of thumb is not take medication during pregnancy before consulting with you OB and pharmacist. ...Read more

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Why did my baby get omphalocele?

Why did my baby get omphalocele?

Unsure : this abdominal defect is not a frequent occurrence, about one:4000 live births. It is associated with other birth defects such as heart, brain, or kidney. ...Read more

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What symptoms suggest omphalocele?

What symptoms suggest omphalocele?

Omphalocele: There are usually no maternal symptoms of a fetal omphalocele. One sign may be an elevation of the alpha-fetal protein (AFP) concentration in maternal blood. AFP is used as a screening test in the midtrimester for neural tube defects. The presence of an omphalocele can also elevate the afp. ...Read more

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What are the symptoms of an omphalocele?

What are the symptoms of an omphalocele?

Abdominal wall defec: Omphalocele is a central abdominal wall defect that results from abdominal contents herniating into the base of the umbilical cord. If the defct is small there may be only intestine in the defect. If it is large it can contain intestine and liver. May be associated with other midline defects. ...Read more

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What do I need to know about baby with omphalocele?

What do I need to know about baby with omphalocele?

See perinatologist: A baby with an omphalocele can have many associated issues, including cardiac, chromosomal, lung, or other additional problems. The key is to be evaluated by a perinatologist, and have a fetal MRI and a cardiac echo. This will allow you to better understand if and what additional issues may be present. Then, meet with a pediatric surgeon and cardiac surgeon if echo abnormal. ...Read more

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