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Doctor insights on: Is There Any Difference Between A Paraganglioma And A Pheochromocytoma

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Is there any difference between a paraganglioma and a pheochromocytoma?

Very similar: The two are closely related and both originate from the same kind of cell (chromaffin cells) but pheochromocytomas secrete catecholamines (adrenalin and noradrenalin) while paragangliomas generally do not. ...Read more

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Dr. Richard Orr
495 doctors shared insights

Pheochromocytoma (Definition)

Pheochromocytoma is a tumor of the adrenal gland. The adrenal glands are small organs that sit above the kidneys and secrete important hormones that are responsible for maintain body fluid and electrolyte levels and helps people respond to stress. A pheochromocytoma can cause the release of too much stress hormone such as epinephrine, leading to periodic increases in blood pressure, flushing, and ...Read more


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 is there any difference between a paraganglioma and a pheochromocytoma?

Yes: Paraganglioma is usually treated surgically and does not make any substances that cause side effects..Like a pheo does...These tumors reak havoc on the person raising blood pressure, heart rate, etc and are sometimes very hard to locate. ...Read more

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Is it possible that them reveal paraganglioma and pheochromocytoma?

Pheochromocytoma: I specialize in this. Happy to do 2nd opinion to help you and your team figure out what is going on. This is a deadly disease. Don't mess with it. ...Read more

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Can a pheochromocytoma or paraganglioma produce important psychiatric symptoms or not?

Can a pheochromocytoma or paraganglioma produce important psychiatric symptoms or not?

Pheochromocytoma: Pheochromocytoma is a tumor of adrenal gland. It can cause psychiatric symptoms, such as anxiety feeling of extreme fright i also has medical symptoms. Please see an endocriniologist for your condition. ...Read more

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What kind of characteristics or experience should I look for in a doctor or a surgeon to quit my pheochromocytoma or paraganglioma?

What kind of characteristics or experience should I look for in a doctor or a surgeon to quit my pheochromocytoma or paraganglioma?

Endocrine surgeon: Several subspecialties deal with pheochromocytoma. Endocrine surgeons work closely with endocrinologists and are therefore best equipped to take care of the entire process. Surgical oncologists and urologists are also trained to deal with this disease. It can be tricky, especially intraoperatively, so i would go to a tertiary center. ...Read more

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Is there any link between adenosine deaminase deficiency and paraganglioma/ pheochromocytoma?

Not that I'm ....: Aware of. Ada deficiency is one of the causes of severe combined immunodeficiency (aka, scid). Paraganglioma has been specifically correlated with mutations in succinate dehydrogenase (sdh) mutations, and likely reflects a link between cell growth/fate specification, epigenetic control of gene expression and metabolism. ...Read more

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I have blood count with differential could they help reveal or diagnose a pheochromocytoma or paraganglioma?

I have blood count with differential could they help reveal or diagnose a pheochromocytoma or paraganglioma?

No: A blood count with a differential reveals the make up of the WBC system indicating the total white blood cell count, how many are polys and how many lymphocytes. To define the presence of a pheochromocytoma or paraganglioma which are adrenal lesions, one has to measure products derived from adrenal tissue, that is the adrenal like substances that are vASOActive. ...Read more

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When should I measure my blood pressure if I have only paroxistic high BP pheochromocytoma or paraganglioma? During an attack?

When should I measure my blood pressure if I have only paroxistic high BP pheochromocytoma or paraganglioma? During an attack?

Anytime: If i understand you correctly, you have paroxysmal hypertension, pheochromocytoma or paraganglioma. The issue is not when to measure your BP but how to make the correct diagnosis. If you have a tumor causing your high BP then it needs to be identified, characterized and removed by a trained surgical oncologist or endocrine surgeon. If you have paroxysmal hypertension then you need a medical doctor. ...Read more

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What is the difference between malignant and benign pheochromocytoma?

What is the difference between malignant and benign pheochromocytoma?

Prognosis: Majority of pheochromocytomas are benign only about 10 % are malignant, one third ( 30 % ) out side adrenal gland tumors are malignant. With 50 % 5 yr survival, also show elivated levels of chromogranin a ...Read more

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