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Doctor insights on: Is There Any Difference Between A Paraganglioma And A Pheochromocytoma

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Is there any difference between a paraganglioma and a pheochromocytoma?

Very similar: The two are closely related and both originate from the same kind of cell (chromaffin cells) but pheochromocytomas secrete catecholamines (adrenalin and noradrenalin) while paragangliomas generally do not. ...Read more

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Dr. Richard Orr
508 doctors shared insights

Pheochromocytoma (Definition)

A tumor of the adrenal gland. The adrenal glands are small organs that sit above the kidneys and secrete important hormones that are responsible for maintain body fluid and electrolyte levels and helps people respond to stress. A pheochromocytoma can cause the release of too much stress hormone such as epinephrine, leading to periodic increases in blood pressure, flushing, and ...Read more


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 is there any difference between a paraganglioma and a pheochromocytoma?

 is there any difference between a paraganglioma and a pheochromocytoma?

Yes: Paraganglioma is usually treated surgically and does not make any substances that cause side effects..Like a pheo does...These tumors reak havoc on the person raising blood pressure, heart rate, etc and are sometimes very hard to locate. ...Read more

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Is it possible that them reveal paraganglioma and pheochromocytoma?

Pheochromocytoma: I specialize in this. Happy to do 2nd opinion to help you and your team figure out what is going on. This is a deadly disease. Don't mess with it. ...Read more

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Can a pheochromocytoma or paraganglioma produce important psychiatric symptoms or not?

Can a pheochromocytoma or paraganglioma produce important psychiatric symptoms or not?

Pheochromocytoma: Pheochromocytoma is a tumor of adrenal gland. It can cause psychiatric symptoms, such as anxiety feeling of extreme fright i also has medical symptoms. Please see an endocriniologist for your condition. ...Read more

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What kind of characteristics or experience should I look for in a doctor or a surgeon to quit my pheochromocytoma or paraganglioma?

What kind of characteristics or experience should I look for in a doctor or a surgeon to quit my pheochromocytoma or paraganglioma?

Endocrine surgeon: Several subspecialties deal with pheochromocytoma. Endocrine surgeons work closely with endocrinologists and are therefore best equipped to take care of the entire process. Surgical oncologists and urologists are also trained to deal with this disease. It can be tricky, especially intraoperatively, so i would go to a tertiary center. ...Read more

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Is there any link between adenosine deaminase deficiency and paraganglioma/ pheochromocytoma?

Not that I'm ....: Aware of. Ada deficiency is one of the causes of severe combined immunodeficiency (aka, scid). Paraganglioma has been specifically correlated with mutations in succinate dehydrogenase (sdh) mutations, and likely reflects a link between cell growth/fate specification, epigenetic control of gene expression and metabolism. ...Read more

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I have blood count with differential could they help reveal or diagnose a pheochromocytoma or paraganglioma?

I have blood count with differential could they help reveal or diagnose a pheochromocytoma or paraganglioma?

No: A blood count with a differential reveals the make up of the WBC system indicating the total white blood cell count, how many are polys and how many lymphocytes. To define the presence of a pheochromocytoma or paraganglioma which are adrenal lesions, one has to measure products derived from adrenal tissue, that is the adrenal like substances that are vASOActive. ...Read more

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When should I measure my blood pressure if I have only paroxistic high BP pheochromocytoma or paraganglioma? During an attack?

When should I measure my blood pressure if I have only paroxistic high BP pheochromocytoma or paraganglioma? During an attack?

Anytime: If i understand you correctly, you have paroxysmal hypertension, pheochromocytoma or paraganglioma. The issue is not when to measure your BP but how to make the correct diagnosis. If you have a tumor causing your high BP then it needs to be identified, characterized and removed by a trained surgical oncologist or endocrine surgeon. If you have paroxysmal hypertension then you need a medical doctor. ...Read more

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What is the difference between malignant and benign pheochromocytoma?

What is the difference between malignant and benign pheochromocytoma?

Prognosis: Majority of pheochromocytomas are benign only about 10 % are malignant, one third ( 30 % ) out side adrenal gland tumors are malignant. With 50 % 5 yr survival, also show elivated levels of chromogranin a ...Read more

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Difference between pheochromocytoma vs. General anxiety disorder?

Big difference: A pheochromocytoma is a serious, but rare, tumor which secretes Adrenalin type of hormones. Anxiety is one of many symptoms. Patients with pheos are treated by endocrinologists and specialized surgeons. An anxiety disorder is a mood disorder diagnosed when other medical causes of anxiety are ruled out. It is often treated by a mental health professional or primary care provider. ...Read more

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Can exertion trigger a Pheochromocytoma episode? Thank you

Can exertion  trigger a Pheochromocytoma episode? Thank you

Yes: This is a tumor of the adrenal gland or sympathetic nervous system that causes overproduction of certain hormones. Exertion can increase the out put of catecholamines from the tumor and increase your blood pressure, cause irregular heart rhythms, etc. You should be on medication to control blood pressure. Have you seen a specialist? You will need surgery to remove the tumor that causes this. ...Read more

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Can a pheochromocytoma cause an isquemic and transitory attack?

Pheo: Yes. A pheochromocytoma can cause a very high spike in blood pressure, which can cause a TIA (transient ischemic attack), or a mini-stroke, or a major stroke, or a heart attack, etc. It can be very dangerous. A pheo is a rather rare disorder, but if you have it, you need attention right away. ...Read more

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I have many of the symptoms of pheochromocytoma. Does this mean that I have it? 

I have many of the symptoms of pheochromocytoma. Does this mean that I have it? 

Get tested: If you have many symptoms of pheochromocytoma, you should see your doctor to get it tested. The workup is complicated but it usually starts with 24 urine test and/or blood test. These tests are very good and if they come back normal (despite you still having symptoms), then it's unlikely that you have pheochromocytoma and it's time to look at other possible causes. ...Read more

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Why are there so many different types of tests for pheochromocytoma? Which is right for me?

Why are there so many different types of tests for pheochromocytoma? Which is right for me?

Confusing diagnosis: There are many screening tests for pheochromocytoma - some are blood tests, some are urine tests. Screening is becoming less burdensome in the last several years because of more sensitive tests. Main question - why are you being screened? Typically it is for symptoms, adrenal mass on ct, or rare familial syndromes (men ii). Good tests are catecholamine and metanephrine levels. ...Read more

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Why are there so many different types of tests for pheochromocytoma, and which ones should I have performed?

Why are there so many different types of tests for pheochromocytoma, and which ones should I have performed?

Two major types: Plasma-free catecholamines (epinephrine and norepinephrine) and metanephrines (metabolites of catecholamines) can be measured after an 'attack' of pheochromocytoma, using a blood sample. This is a very useful test, simple to collect. Alternatively, 24-hour urine testing for catechol and metaneph can also be helpful after an 'attack'. Other testing using drugs are complicated and rarely needed. ...Read more

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Will pheochromocytoma kill me?

Do you have one?: These are killers if neglected. You'll either have a hemorrhagic stroke, or become demented from the wild changes in blood pressure, or have your heart muscle fail from the excess catecholamines, or get heart failure from hypertension. None of these are pleasant. If you are offered surgery, take it. ...Read more

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What specialist treats a pheochromocytoma?

Endo and surgeon: Pheochromocytomas need to be surgically removed, but the patient needs to be given certain types of blood pressure medications before hand. A surgeon experienced in pheos and an endocrinologist need to be part of your health care team. ...Read more

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What ?Will cure malignant pheochromocytoma?

Surgery: Hopefully it can be diagnosed before it has spread, most are diagnosed by a good history and physical exam that may show difficult to control HTN , ct scan which shows an adrenal mass, and blood and/ or urine studies to confirm the diagnoses. These adrenal tumors can be removed by either the laparoscopic or open surgery approach. ...Read more