Doctor insights on:
Is There A More Powerful Version Of Amitriptyline For Curing Chronic Pain
No: Amitriptyline is a tricyclic antidepressant, similar to drugs such as Cymbalta (duloxetine) and savella (milnacipran) which are known as snris (serotonin/norepinephrine reuptake inhibitors). None cure pain; they increase nerve chemicals that decrease pain. You may respond better to one vs. Another but none are "more powerful" than any other. The snris are touted to have less side effects. ...Read moreSee 1 more doctor answer
Of course: When used in the management of a patient with chronic musculoskeletal pain, amitriptyline may decrease pain, improve depression, improve sleep and provide some muscle relaxation. Amitriptyline should not be abruptly discontinued to avoid withdrawal symptoms (e.g., malaise, insomnia, drowsiness, muscle aches). ...Read more
Yes: Depends on the cause of pain. Depression causes the perception of pain to be worse for the patient. The major classes of antidepressants are: tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, norepinephrine reuptake inhibitors, serotonin receptor modulators. Your doctor will have to sort out which medication is right for you. ...Read moreSee 1 more doctor answer
If chronic pain is caused by the CNS getting "wound up" . Do the drugs like amitriptyline act by essentially "winding down" the CNS or pain signals ?
Is 50 mg amitriptyline taken at bedtime good for chronic ankle pain? After my first dose, I'm pain free but extremely sleepy. Is that result of dose
Chronic ankle pain: Best approach is to find the cause of the chronic ankle pain and treat it at the root. Topical medications may prove to be beneficial and help avert systemic side effects. Feeling sleepy is a common side effect of Amitriptyline. Your doctor may suggest starting it at a lower dose such as 10 or 25 mg at bedtime and titrating upwards as indicated and as tolerated. ...Read more
Could I use Zoloft and amitriptyline at the same time ? Zoloft for anxiety/depression and amitriptyline for chronic idiopathic nerve pain ?
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