Doctor insights on:
Is There A Homeopathic Alternative For Aromatase Inhibitors
No: If you have been prescribed aromatase inhibitors, presumably you have hormone sensitive breast cancer. Do not substitute the homeopathic placebo for your medications. The data on breast cancer treatment is solid for aromatase inhibitors and using a homeopathic placebo might prove lethal. ...Read moreSee 1 more doctor answer
Benefits > downsides: Hormonal therapy has systemic benefits in er+ patients (similar to chemo), reduces local recurrence after breast conservation, and reduces the risk of second/new breast cancers. Head to head each of these is slightly better for ais than tamoxifen. Ais major side effects are menopausal symptoms, bone and joint symptoms (arthralgias), and decrease in bone density. ...Read moreSee 1 more doctor answer
Maybe but for what?: All medications, prescription & otc, as well as all dietary supplements, have potential side effects. There is no free lunch, no side effect free pill, whether medication or supplement. Aromatase inhibitors are approved for use in breast cancer in which case the potential risk of liver damage, hypertension, etc probably outweighs risk of recurrent breast cancer. So talk to your doc re what's right. ...Read more
May be effective: For boys with short stature, and no other known cause, aromatase inhibitors have been used. It is still considered experimental, and it is not clear that it will increase adult height. Much depends on the specific condition. As with anything that may increase testosterone, there are side effects. You should only do this under the care/supervision of a pediatric endocrinologist. ...Read more
Probably never will: Many of the drugs we use in pediatric oncology are never approved by the fda for treatment of a particular pediatric cancer. Once it gains fda approval for an adult disease indication, we then can study it in clinical trials, and if warranted, use it. ...Read moreSee 2 more doctor answers
Need help in reducing e2 (oestradiol). Need some advice in dosing aromatase inhibitors. Tried arimidex as well as aromasin but got bone mineral loss..
Go see your doctor: Presumably you're taking Arimidex (anastrozole) to control your Estradiol to treat gynecomastia (rather than trying to jack up your testosterone). Loss of bone mineral density is a known consequence of excessively lowering one's estradiol. I'm not clear what kind of trouble you're having w/your dosing since you didn't mention your regimen. Regardless, you need to address your concern w/your doctor. ...Read more
Aromatase: FTM requires two things: 1: I do not take care of such patients unless I am notified by a Psychologist who is taking care of the patient. 2: I do not see any indication for aromatase inhibitors to be given in addition to testosterone. I have been fortunate to have reasonable success with FTM and MTF. ...Read more
No: Tamoxifen belongs to a class of drugs called selective estrogen receptor modulators (serms). It works by blocking the binding of estrogen to estrogen receptors, thus disabling hormone-sensitive breast cancer cells. Aromatase inhibitors block the conversion of androgens to estrogens, effectively removing estrogen from the body (in postmenopausal women). ...Read moreSee 1 more doctor answer
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