Doctor insights on:
Is There A Genetic Test That Shows Who Is At Risk For Osteogenic Sarcoma
Prenatal testing for genetic problems may be done before or after conception. Testing for spina bifida or Down syndrome is done after a pregnancy is established. Besides the couples listed above, counseling and diagnosis are also recommended for mothers over the age of 35, and those who have received abnormal screening test results, such as alpha-fetoprotein (AFP). For more information about the alpha-fetoprotein test, and when and why you might have it, see alpha-fetoprotein. For those who may be at risk, genetic counseling and prenatal diagnosis are used to help ...Read more
Bone cancer: Osteogenic sarcoma, or osteosarcoma, is a rare cancer. It forms bone tissue (when examined under a microscope) and usually arises in bone around knee or shoulder. Rarely, osteosarcoma may arise in the soft tissues. Most of the time there are random mutations causing the tumor but in rare cases there is a genetic mutation predisposing the patient. It is most common in teenagers and young adults. ...Read moreSee 1 more doctor answer
Treatable: Not too long ago osteogenic sarcoma used to be almost uniformly fatal. But with chemotherapy regimens now available, the majority of patients can be cured. Surgery is also required and in most cases the tumor can be removed while keeping the limb. While it is a very serious cancer, we now have very good treatment options available. ...Read moreSee 1 more doctor answer
My sister was diagnosed with bone cancer (osteogenic sarcoma). What can you tell me about this kind of cancer?
In order 2 answer-: -this an orthopedic surgeon has 2 B blunt. First of all B sure she is Cing an ortho oncologist who deals with bone Ca. The outlook is grim especially if it is located closer 2 the body, a distal tibia is better than in the prox femur. Cures R rare, but with no metastatic disease & eary amputation, U have the best chance 4 more time 2 live. By time Dx is made, spread is usually all ready present. ...Read more
Yes.: The two are synonyms. By definition, it is a sarcoma that produces malignant osteoid (immature bone) that is seen under the microsope. Osteogenic means "producing bone." other bone sarcomas, like ewing's, do not produce osteoid. Most arise in bone, but there are rare soft tissue osteosarcomas (or osteogenic sarcomas, depending on which term you prefer). ...Read moreSee 2 more doctor answers
Resect if possible: Primary ostogenic sarcoma uually ound in younger patients and is best handled by resection. What has made things easier to control is the ability to employ radiation and chemo to reduce the lesion if possible. In the upper extremity where such lesions appear a Tikoff resection is best employed. In the lower extremity resection handled by various prosthesis including whole femur replacement. ...Read more
My sister-in law was diagnosed with bone cancer (osteogenic sarcoma)? How good is the survival for this?
Variable: Most patients with osteogenic sarcomas can be cured and have a normal life span. Chemotherapy and surgery are required. Even in cases where sarcoma had spread, cure can sometimes be achieved. In cases where it cannot be cured, patients may live from weeks to years. Each case is different. Nobody can predict survival of any one patient. We only know statistics for large groups. Good luck! ...Read moreSee 1 more doctor answer
I had osteogenic sarcoma, with a van nes rotation amputation. My hip has a bursa and steroid injections have stopped working. How can I get rid of it?
Friend has osteogenic sarcoma had below knee amputation 4 days ago. She is already home and has a prosthetic. What happens now? They removed all tumor
Is there a genetic test that shows who is more at risk for certain cancers, even without family history of them?
Had a genetic test done to see what antidepressants/antipsych that will show which are good/bad for me. From my research seems like waste of time?
It can actually: Be helpful for some people. It can help to guide medication choice rather than losing time on medication trials for meds that don't work out. Take care. ...Read more
Has anyone had or heard of a genetic test you can have to see if you are at risk for breast cancer?
BrCA 1 and 2: We can test forcertaintypes of hereditary breast cancer caused by the brca genes 1 and 2. There is also a test for lynch syndrome that causes increased risk of polyposis colorectal cancer, breast, and uterine cancer. Tests are available for li fraumeni which is very rare. We think that more (and cheaper) genetic testing will be available in the next several years. ...Read moreSee 1 more doctor answer
No: Children born with open spina bifida are at increased risk for chiari type 2 due to lower position of posterior brain structures. There may be some increased risk for this problem in some families but there is a nutritional role and other factors also. Adults without any spina bifida history can get chiari type 1. There is no firm genetic pattern that is predictive of the chiari type 1. ...Read moreSee 1 more doctor answer
Yes and No: Genes have been identified which increase one's predisposition to alcoholism. Like many complex medical conditions, alcoholism is due to a combination of genes and environmental factors. Factors like life style, stress, exercise, and social support can have a large influence on whether someone with a predisposition actually becomes an alcoholic. ...Read moreSee 1 more doctor answer
Not that I am aware: Some people are keloid formers and others are not. Keloids are more likely to form in areas of high use as well. If you form keloids, consider a more balanced alkaline diet (you can google alkaline diet). Acupuncture is amazing at reducing keloids! I am unaware of a genetic test. Most are expensive, usually not covered by insurance and not necessary when these other things work so well. ...Read more
Yes: Hemolytic disease of the newborn, causing yellow skin and eyes (jaundice) with anemia, is most commonly due to a "set-up"--a blood type difference between mother and child. Blood types are caused by genes at the ABO and other loci (rhesus being most damaging), with o type or rh negative moms making antibodies to red blood cells of a or b or rh+ fetuses (if mom is o and fetus ab, baby switched), . ...Read more
Is there a genetic test in UK that can tell if a person is a poor metabolizer with Clopidogrel having two copies of each of the CYP2C19 gene.?
Phenotype is the big: Issue, not genotype, because we each live with the complex results of both genotype combined with all our complex internal controls, beyond the any gene or sets of genes alone. Since clopidgrel is a platelet suppressing, clot-slowing agent, best check clotting with & without whatever trial dosage. The best of the clotting tests is TEG, study: Thromboelastography, commonly used in hospitals. ...Read more
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more
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