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Doctor insights on: Is There A Genetic Component To Leukemia

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Is there a genetic component to leukemia?

Is there a genetic component to leukemia?

There can be: But not in the sense that it is inherited within family members. An example is those individuals affected by down's syndrome have an abnormal chromosome and acute leukemia has a higher incidence in this population. ...Read more

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Dr. Liawaty Ho
1,118 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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Is acute pro-mylocytic leukemia inherited decease? Is it a genetic disorder?

Is acute pro-mylocytic leukemia inherited decease? Is it a genetic disorder?

No: It is not inherited and not 'genetic' in the sense that you pass it on between generations. There is a specific genetic abnormality that develops that drives the disease when chromosomes 15 and 17 get tangled up. ...Read more

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Great uncle and his daughter both diagnosed with acute apl leukemia in their 50s. Is this genetic? Environmental?Should i worry?

Genetic Counseling: It is best to see a genetic counselor that is often associated with cancer treatment programs that can help answer these questions after a thorough evaluation of the family history. In general, most cancers don't have a familial disposition. ...Read more

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If leukemia is genetic how is it not hereditary?

If leukemia is genetic how is it not hereditary?

See below. : The genetics of the leukemia are acquired by the leukemia cells. This creates genetic abnormalities in the leukemia cells, but you are not born with these genetic abnormalities. Neither the genetic abnormality of the leukemia nor the predisposition to acquire this disease is hereditary that we know of. ...Read more

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How can I get a genetic test done to determine if I am a carrier of a leukemia genetic mutation?

How can I get a genetic test done to determine if I am a carrier of a leukemia genetic mutation?

No reliable test: There is no test like that. There are companies offering comprehensive genomic mapping etc- however, i would not recommend it as it is not primetime yet. There are a lot of questions in regard to that - ie. Not clear how reliable it is, how would you interprete the result , what is the consequency etc. It is for sure will increase your anxiety level. Discuss with your md in detail. ...Read more

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What can I do to get a genetic test done to determine if I am a carrier of the leukemia genetic mutation?

What can I do to get a genetic test done to determine if I am a carrier of the leukemia genetic mutation?

What test?: What "leukemia genetic mutation" are you referring to? I am unaware of any screening test, where screeening is defined as testing in an asymptomatic patient. Need more info... ...Read more

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Is chronic myelogenous leukemia classified as a genetic abnormality or a genetic disorder?

Is chronic myelogenous leukemia classified as a genetic abnormality or a genetic disorder?

Yes.: CML = genetic abnormality or a genetic disorder? I'm not sure what the difference is, but i'll try to extend what i think you are asking. CML is an acquired genetic abnormality. It is not (generally) an inheritied genetic trait/disorder. ...Read more

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Is acute erythroid leukemia genetic? My father was just diagnosed at age 70. I am 31 low platelets run extremely low in my family (dads side).

Is acute erythroid leukemia genetic? My father was just diagnosed at age 70. I am 31 low platelets run extremely low in my family (dads side).

It is possible...: Familial cases of erythroleukemia (m6) have been described. M6 itself is relatively rare, and familial cases even more rare. Usually, m6 develops in patients with pre-existing myelodysplastic syndrome (pre-leukemic state). Familial types of myelodysplastic syndromes do occur, and would be a risk for developing leukemia. Talk to your doctor about your worries and if any further testing is need. ...Read more

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Mother diagnosis breast ca@ 53, maternal grandpa colon ca at 87, maternal great uncle diagnosis acute leukemia at 65 and his daughter now has acute leuk too.Genetic?

Mother diagnosis breast ca@ 53, maternal grandpa colon ca at 87, maternal great uncle diagnosis acute leukemia at 65 and his daughter now has acute leuk too.Genetic?

May be or may not: May be related , some colon cancers and breast cancers are genetic origin, environmental exposure is responsible for leukemias but genetic factor is also involved.What you have to worry brca i & ! genes you may be carrying , from inf. You gave , does not like you have speak to your doctor, whether you are a candidate for genetic tests (expensive ins may not cover ). ...Read more

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


Genetic Linkage (Definition)

Genetic linkage is the tendency of genes that are located proximal to each other on a chromosome to be inherited together during meiosis. Genes whose loci are nearer to each other are less likely to be separated onto different chromatids during chromosomal crossover, and are therefore said ...Read more