Doctor insights on:
Is There A Genetic Component To Leukemia
Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
See below. : The genetics of the leukemia are acquired by the leukemia cells. This creates genetic abnormalities in the leukemia cells, but you are not born with these genetic abnormalities. Neither the genetic abnormality of the leukemia nor the predisposition to acquire this disease is hereditary that we know of. ...Read moreSee 1 more doctor answer
No reliable test: There is no test like that. There are companies offering comprehensive genomic mapping etc- however, i would not recommend it as it is not primetime yet. There are a lot of questions in regard to that - ie. Not clear how reliable it is, how would you interprete the result , what is the consequency etc. It is for sure will increase your anxiety level. Discuss with your md in detail. ...Read more
What can I do to get a genetic test done to determine if I am a carrier of the leukemia genetic mutation?
My moms uncle and his daughter both had leukemia at 65 and 54 years old. He had aml and she had apl. What would cause this? Genetic?
Yes: genetics and gene inheritance is the most important factor ...Read more
Is acute erythroid leukemia genetic? My father was just diagnosed at age 70. I am 31 low platelets run extremely low in my family (dads side).
It is possible...: Familial cases of erythroleukemia (m6) have been described. M6 itself is relatively rare, and familial cases even more rare. Usually, m6 develops in patients with pre-existing myelodysplastic syndrome (pre-leukemic state). Familial types of myelodysplastic syndromes do occur, and would be a risk for developing leukemia. Talk to your doctor about your worries and if any further testing is need. ...Read more
Mother diagnosis breast ca@ 53, maternal grandpa colon ca at 87, maternal great uncle diagnosis acute leukemia at 65 and his daughter now has acute leuk too.Genetic?
May be or may not: May be related , some colon cancers and breast cancers are genetic origin, environmental exposure is responsible for leukemias but genetic factor is also involved.What you have to worry brca i & ! genes you may be carrying , from inf. You gave , does not like you have speak to your doctor, whether you are a candidate for genetic tests (expensive ins may not cover ). ...Read more
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
Genetic linkage is the tendency of genes that are located proximal to each other on a chromosome to be inherited together during meiosis. Genes whose loci are nearer to each other are less likely to be separated onto different chromatids during chromosomal crossover, and are therefore said ...Read more
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