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Doctor insights on: Is Thalassemia Major Curable By Anything Other Than Bone Marrow Transplant

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Dr. Mark Pack
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


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Sickle cell disease - is it curable with a bone marrow transplant?

Sickle cell disease - is it curable with a bone marrow transplant?

I do not know.: Most patients with sickle cell diseaes have a very benign manifestation of the diseas (trait) and they can live close to a normal life. E few percentage of this people has severe disease. I do not have experience with bone marrow transplant for sickle cell disease. ...Read more

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What are the side effects of bone marrow transplantation tor thalassemia?

Many possible: Possible side effects from a bone marrow transplant include: rejection of the donor marrow, graft vs. Host disease (donor cells attack the recipient), infections (bacterial, viral, fungal, etc...), mouth sores, stomach ulcers, diarrhea, liver disease, seizures, nerve pain, lung inflammation, hormonal deficiencies, osteoporosis, future cancers, etc... ...Read more

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How long does it take to become transfusion independent after the bone marrow transplantation for thalassemia?

How long does it take to become transfusion independent after the bone marrow transplantation for thalassemia?

About 1-3 months: The seattle cancer care alliance site has information on bone marrow transplants: www.Seattlecca.Org the time after transplant is the "engraftment" period (1.5-4 wk) when doctors watch for the transplant to "take" and grow inside the patient. After engraftment, there is a 3 month recovery period when the patient lives near the hospital and is monitored for growth of his new bone marrow. ...Read more

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What is the success rate of bone marrow transplantation for thalassemia?

What is the success rate of bone marrow transplantation for thalassemia?

Depends: The bone marrow transplant team at each transplant center can give details of how many of their transplants "take" and how many are "rejected" after transplantation. The numbers may be different for stem cells from umbilical cord blood compared to stem cells from donor bone marrow. The better the match between donor and patient, the less likely a rejection will occur. ...Read more

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How long must the child stay in hospital after the bone marrow transplantation for thalassemia?

How long must the child stay in hospital after the bone marrow transplantation for thalassemia?

Varies a lot: The hospitalization duration for a bone marrow transplant varies a lot, depending on the type of complications, such as infections and graft vs. Host reactions, one has after the transplant. A rough estimate is 6-12 weeks. Sometimes, problems occur after leaving discharge, and a patient has to go right back into the hospital. ...Read more

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What is the cost of bone marrow transplantation for thalassemia?

What is the cost of bone marrow transplantation for thalassemia?

Not sure: Cost vary for bone marrow transplantation, depending on the number of hospital days, number of ICU (intensive care unit) days, complications, rejection events, infections, etc... The bone marrow transplant team at each transplant center can give details of costs. A rough estimate would be a quarter million dollars or more. ...Read more

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My 9yrs old son suffering from thalassemia pl suggest cheap and best bone marrow transplantation centre?

Hmmm...: Your request raises several questions. I assume your child has beta-thal major; that is the only thal diagnosis where a bmt might be appropriate therapy for a 9 year old. Why a "cheap" place? Bmt is a serious procedure, and is not one to consider trying to pay for yourself. If this is medically indicated go to a good program like seattle and have them help you figure out how to pay for it! ...Read more

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How much does a bone marrow transplant cost if uninsured?

Too much.: A bmt and all of the aftercare needed would be very expensive, easily in the hundreds of thousands of dollars if paid for at "standard rates." insurance companies negotiate rates for transplants on behalf of their beneficiaries, but it still is very expensive. Sometimes academic will agree to give charity care, but a bmt would be beyond what they usually do. ...Read more

Dr. Keith Stockerl-Goldstein
104 doctors shared insights

Bone Marrow Transplant (Definition)

This refers to using chemotherapy and/or radiation therapy to treat patients and then replacing their bone marrow cells with their own stem cells (autologous transplant) or a donors stem cells (allogeneic transplant). Bone marrow transplant generally refers to using bone marrow cells but is often used when using stem cells collected ...Read more


Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more