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Doctor insights on: Is Thalassemia Major A Problem In Pregnancy

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Is thalassemia major a problem in pregnancy?

Is thalassemia major a problem in pregnancy?

Thal major...: ...Is always a problem, but a good outcome is common: http://www.Thalassemia.Org/index.Php?Option=com_content&view=article&id=297:study-looks-at-pregnancy-in-thalassemia&catid=1:latest-news. ...Read more

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Dr. William Singer
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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Is it a concern of having hypoglycemia in children?

Is it a concern of having hypoglycemia in children?

Yes: Hypoglycemia in anyone, including children, can suggest an underlying metabolic problem including Insulin resistance or other pancreatic problems. Hypoglycemia in anyone should be further evaluated by your doctor. ...Read more

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Is teen pregnancy a problem in the world?

Is teen pregnancy a problem in the world?

Yes: People becoming pregnant before they have the ability to care adequately for the child is a worldwide problem. ...Read more

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Is hydrocele in a fetus a problem?

Is hydrocele in a fetus a problem?

Usually not: Will probably be present at birth. Most infant hydroceles resolve spontaneously during first year of life. May need treatment if they enlarge hugely or become tense, tender or red. ...Read more

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What is a clotting factor deficiency in a child?

What is a clotting factor deficiency in a child?

Depends on which : Factor. There are about a dozen clotting factors and any of those could be deficient. Some are serious others not so much. It is not feasible to provide specific suggestion from the information provided. ...Read more

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Is a woman with sc blood genotype a sickle cell carrier or patient. And what is the health implication of this especially during pregnancy?

Is a woman with sc blood genotype a sickle cell carrier or patient. And what is the health implication of this especially during pregnancy?

Hgb SC: Is a sickle cell syndrome but the genetics are different. A woman with HGB sc will pass either a HGB s gene, or a HGB c gene to her child. It is important to know what kind of HGB the father has-he should have a hemoglobin electrophoresis to find out how the child might be affected. Pregnancy complications are rare, but the baby can have a low weight, and rarely there are complications for the mom. ...Read more

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Is hydroureter in a fetus a problem?

Is hydroureter in a fetus a problem?

Yes: That would indicate some type obstruction in the fetal excretory system that may require intrauterine treatment. ...Read more

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What is a major factor in low birth weight?

What is a major factor in low birth weight?

Major Factor: Low birth weight has multiple causes. Utero placental insufficiency being the ultimate culprit. In truth there are many major factors that cause low birth weight. In our present day, in our community i must say that the major factor responsible for lbw is cigarette smoking. ...Read more

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Is there a medical condition that only allows a female to be pregnant with a child of one particular sex?

Is there a medical condition that only allows a female to be pregnant with a child of one particular sex?

Rare: In theory, if a woman carries an sex chromosome disorder called "X linked recessive", she can give birth to normal females or females who carry the abnormal X, but cause significant defects or be lethal (abort) a male conceptus that did not have a normal X to cancel it's effect. ...Read more

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Is a result of 100% antibodies in a seminal fluid test for infertility a permanent problem or is the only way for pregnancy ivf? Thanks

Is a result of 100% antibodies in a seminal fluid test for infertility a permanent problem or is the only way for pregnancy ivf?  Thanks

Maybe IVF: It depends on what testing you are referring to, as there are several ways to perform this test. In some cases, it may refer to 100% being free, which would be normal. 100% affected on the other hand would not be good. It is not absolute that one could not conceive with iui, but with high antibodies, there is a decreased chance outside of ivf. ...Read more

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Haemoglobin is not found in the urine of a healthy person but is in a person with hemolytic anemia, is this true?

Haemoglobin is not found in the urine of a healthy person but is in a person with hemolytic anemia, is this true?

It's not so simple: Everyone has a little bit of blood in the urine. A runner usually has mild hematuria from the mechanics of running with a full bladder. Further, someone who has hemolysis that's not intravascular (i.e., autoimmune hemolysis, spherocytosis) won't spill hemoglobin, and somone with mild ongoing hemolysis (sickle cell) with enough haptoglobin to trap the hemoglobin won't spill it either. ...Read more

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Is carrying low a concern in pregnancy?

Is carrying low a concern in pregnancy?

No: How you carry the pregnancy has nothing to do with outcomes. If you are having symptoms of pelvic pressure or contractions, for example, then you need to seek help. ...Read more

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There is blood block in brain, what treatment s d best? Is it a very serious problem or a small problem which can be solved?

There is blood block in brain, what treatment s d best? Is it a very serious problem or a small problem which can be solved?

Worrisome: Blocks are strokes - is this the cause of your weakness?You may recover and never have another, but this could also be a warning of another stroke and that could cause loss of function that might not recover. Control your high BP and you may be started on aspirin. At the time of a stroke, you may start on blood thinners and tpa (alteplase). Post stroke rehab activities are valuable but may take effort. ...Read more

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Is spotting a major symptom of an ectopic pregnancy?

Is spotting a major symptom of an ectopic pregnancy?

Yes: The majority of ectopic pregnancies present with persistent vaginal bleeding and spotting. However. About one in three women with a normal pregnancy will also have spotting. The safe thing to do is to see your doctor. ...Read more

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If a thalassemia major patient married a normal guy, will the thalassemia be passed down?

If a thalassemia major patient married a normal guy, will the thalassemia be passed down?

If the partner...: ...Has thalassemia trait or another hemoglobin disease, the child can be anemic. Otherwise the child will probably have thalassemia trait or thalassemia minor - not actually sick, but capable of having affected children with another carrier. ...Read more

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Is a heart block a one time thing or a chronic disorder in the heart?

Is a heart block a one time thing or a chronic disorder in the heart?

"Depends": Heart blocks are very variable from fairly benign (first degree) to pretty serious (complete heart block). They can be transient and benign like mobitz type 1 or they can be permanent. Some heart blocks may be more serious but can be reversed if their is an underlying problem such as lyme disease or medication reaction. Often times however a pacemaker may need to be implanted. ...Read more

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Is thalassemia major a problem in pregnancy?

Thal major...: ...Is always a problem, but a good outcome is common: http://www.Thalassemia.Org/index.Php?Option=com_content&view=article&id=297:study-looks-at-pregnancy-in-thalassemia&catid=1:latest-news. ...Read more

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If a thalassemia major patient married a normal guy, will the thalassemia be passed down?

If the partner...: ...Has thalassemia trait or another hemoglobin disease, the child can be anemic. Otherwise the child will probably have thalassemia trait or thalassemia minor - not actually sick, but capable of having affected children with another carrier. ...Read more

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What are the symptoms of thalassemia major?

What are the symptoms of thalassemia major?

See below: The most severe form of Alpha thalassemia major causes stillbirth (death of the unborn baby during birth or the late stages of pregnancy). Children born with thalessemia major (cooley's anemia) are normal at birth, but develop severe anemia during the first year of life. Other symptoms can include: •bone deformities in the face •fatigue •growth failure •shortness of breath •yellow skin. ...Read more

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Is there is any cure for thalassemia major?

Bone marrow transpla: The only present cure for thalassemia major is through bone marrow transplant. This delicate procedure is quite risky even in he best hands but can be life saving if a donor match is found. ...Read more

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Can thalassemia minor change into thalassemia major?

Can thalassemia minor change into thalassemia major?

No: Thalassemia minor is a heterozygous condition and thalassemia major is homozygous and a person is born with the defect. One does not turn into the other. ...Read more

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Is beta thalassemia major andd hb e/beta thalassemia same?

Not the same.: Hemoglobin e is found in the asian population frequently and may be seen with thal trait. Thal major is a serious problem requiring much intervention, including transfusions and frequently splenectomy. Your doctor should be your guiding you. Pregnancy needs to be discussed with your doctor. ...Read more

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Which blood test should be done to detect if thalassemia-major or minor?

Electrophoresis: Usually, the type of thalassemia can be determined by a blood smear accompanied by hemoglobin electrophoresis. A laboratory physician can interpret the results and determine what hemoglobin abnormality is present. For certain types of disease, a genetic test may be necessary. ...Read more

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What if a patient with thalassemia major starts to have a high bilirubin?

What if a patient with thalassemia major starts to have a high bilirubin?

Several reasons: Many patients with thalassemia will have elevated bilirubin from the start. This can be made worse here and there from certain experiences which cause the body to breakdown blood cells more rapidly (infection, new medications). Also, if the bilirubin has been climbing, i would check the health of the liver. This can be done with blood tests, mris and possibly biopsies. ...Read more

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What blood test should be done to detect if a person is thalassemia-major or minor?

Hgb A2 and Hgb F: Thalassemia is a genetic disease and depending of the genetic type it will be major or minor. Anemia is severe plus others serious symptoms, splenomegaly, growth retardation, abnormal bone marrow.The level of serum bilirubin, iron and ferritin are elevated. Bone marrow study reveals market erythroid hyperplasia. The minor type has a benign course. Complete blood count is an important test also. ...Read more

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My child is suffering from thalassemia major & advised for a spleen removal operation after few weeks, is this normal?

Thalassemia Major: Treatment for thalassemia major often involves regular blood transfusions and folate (folic acid) supplements. If you receive blood transfusions, you should not take iron supplements. Doing so can cause a high amount of iron to build up in the body, which can be harmful. Persons who receive significant numbers of blood transfusions need a treatment called chelation therapy to remove excess iron from the body. ...Read more

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What are the most common symptoms of beta-thalassemia major?

What are the most common symptoms of beta-thalassemia major?

Anemia symptoms: The symptoms of beta thalassemia major are those of severe anemia, which include weakness, pallor (pale appearance), decreased growth/development, rapid heart rate, exercise intolerance, thickened bones as the marrow enlarges to try to make more blood cells, enlarged spleen, etc... ...Read more

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How long after birth does a child who inherited thalassemia major show symptoms?

6-8 months for beta: Alpha thalassemia major is generally fatal before birth, with just rare cases born alive. Beta thalassemia major babies look normal at birth because fetal hemoglobin doesn't need beta globulin. As fetal hemoglobin goes away and adult hemoglobin starts being made, the baby will feel the effects of his lack of beta globulin. Symptoms start after the first 6-8 months of life. ...Read more

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Could a person on their 20's have any chance of living with beta thalassemia major?

Could a person on their 20's have any chance of living with beta thalassemia major?

Yes: It's a horrible disease but the newer remedies are helping these folks live longer and better. ...Read more

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After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

6-8 months for beta: Alpha thalassemia major is generally fatal before birth, with just rare cases born alive. Beta thalassemia major babies look normal at birth because fetal hemoglobin doesn't need beta globulin. As fetal hemoglobin goes away and adult hemoglobin starts being made, the baby will feel the effects of his lack of beta globulin. Symptoms start after the first 6-8 months of life. ...Read more

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Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

9-12 months old: Children with beta-thalassemia major usually demonstrate no initial symptoms until the later part of the first year of life (when beta chains are needed to pair with Alpha chains to form hemoglobin (hb) a, after gamma chains production is turned off). ...Read more

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Hello, my brother is having thalassemia major from 20 yrs, can we give him niacin b3 will it help for him, and the iron level is also high in his body.?

Hello, 
my brother is having thalassemia major from 20 yrs, can we give him niacin b3 will it help for him, and the iron level is also high in his body.?

Thalassemia major: He will need to be on iron chelator- that is for sure- to help reduce the iron overload that he has. Discuss this with his doctor- if he is not taking iron chelator agent yet. As far as Niacin b3, - he can actually take vitamin b-complex- once a day . Inside vit b complex- there are vit b12, b6, as well as b2, b3, etc. ...Read more

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People with thalassemia or hemolytic anemia, why they present usually with hemoglobinuria ? Inspite they have reduced rbcs !

Hemoglobinuria....: Is simply the presence of hemoglobin in the urine, and can be seen in any condition that results in intravascular hemolysis. It is not a specific finding. Indeed it can be seen in thalassemias, where red cells are more prone to oxidant stress and mechanical disruption. There many intrinsic and extrinsic reasons for hemolysis to occur. Hope this helps. ...Read more

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A case of immune hemolytic anemia - chances of becoming pregnant? care during pregnancy

A case of immune hemolytic anemia - chances of becoming pregnant? care during pregnancy

Should be able to: Having a hemolytic anemia should not affect the ability to get pregnant. However, your hematologist will need to monitor your blood closely. May need extra folic acid. Hope this helps. ...Read more

Dr. Michael Engel
272 doctors shared insights

Thalassemia (Definition)

An inherited condition ...Read more