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Doctor insights on: Is Thalassemia Dominant Or Recessive

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Is the beta-thalassemia gene recessive or dominant?

Is the beta-thalassemia gene recessive or dominant?

Neither: People normally have 2 beta globulin genes. A mutation in one or both genes leads to 3 levels of beta thalassemia. The genetics of the disorder is not all-or-none nor dominant-recessive. Instead, more or worse mutations causes worse disease. One mutation = beta thal trait (mild symptoms), 2 mutations = beta thal intermedia (transfusions sometimes) or beta thal major (lifelong transfusions needed). ...Read more

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Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

Thalassemia is sever anemia,it ...Read more


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Is edward's syndrome autosomal or sex-linked? Dominant or recessive?

Is edward's syndrome autosomal or sex-linked? Dominant or recessive?

None of the above: Edward syndrome is brought on by an abnormality of chromosome numbers, specifically an extra 18. The abnormal egg with a single chromosome 1-17 & 19-22 + x has a pair of 18's. When the sperm brings a single chromosome 1-22 + x or y then the embryo ends up with 47 chromosomes rather than 46 in every cell.(3-18's) the excess distorts the organ building information & defects arise. ...Read more

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How can a pedigree help you understand if a disease is autosomal dominant or recessive?

How can a pedigree help you understand if a disease is autosomal dominant or recessive?

See below: In brief, in case of a dominant gene, at least one of the parents has the relevant disease. In case of recessive gene both parents can be normal. See this site for an introduction to the topic. https://www.ndsu.edu/pubweb/~mcclean/plsc431/mendel/mendel9.htm ...Read more

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Is turner's syndrome dominant or recessive?

Is turner's syndrome dominant or recessive?

Neither: Turner syndrome is not caused by a variation of a gene, or a mutation of a gene. Therefore, Turner syndrome is neither dominant or recessive, but instead is a type of aneuploidy. Aneuploidy means there is an abnormal number of chromosomes. Turner syndrome's type of aneuploidy is "monosomy X", which means having only one X chromosome, and no Y nor a second X chromosome. ...Read more

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Hello docs, is achondroplasia dominant or recessive?

Autosomal dominant: It is an autosomal dominant disorder. There is high risk of spontaneous mutations. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/001577.htm. ...Read more

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Is Down syndrome dominant or recessive?

Is Down syndrome dominant or recessive?

Neither: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg & the male 21 joins the female pair & creates an embryo with 3 number 21's. ...Read more

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Is angelman syndrome dominant or recessive?

Neither: Angelman's syndrome doesn't follow simple mendelian genetics. Rather, it's due to de novo single genetic mutations, translocational errors, chromosomal abnormalities, or more commonly epi-genetic mutations such as changes in dna methylation. ...Read more

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