Doctor insights on:
Is Taxol And Tamoxifen The Same Drug
This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more
My dr. Wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this healthy?
Benefit/risk: Tamoxifen is a SEAM (selective estrogen receptor modulator). It inhibits estrogen receptor pathway in breast, but stimulates it in ovary and uterus. It may increase fertility for a time, but reduce later due to constant stimulating. Its stimulating effect can also increase risk of uterine cancer. Other side effects from tamoxifen include thrombosis, stroke, etc, esp at long-term use. Read moreSee 1 more doctor answer
What do you suggest if my dr. Wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this ok?
Yes: Tamoxifen is used to prevent breast cancer where it suppresses estrogen binding, it can act as an estrogenic stimulus on ovarian tissue initiating ovulation induction by a mechanism similar to clomiphene citrate. This drug Clomid is able to bind to estrogen receptors in the hypothalamus. Preventing the brain from seeing the negative signal from estrogen This stimulates production of FSH. Read more
Immediately a breast cancer survivor. On the drug tamoxifen, I missed a day. Can I take 2 pills in one day?
No...: No, if you missed it completely do not double up. In the future if you miss a dose and remember within 8 hours you can take the dose. A weekly pill case can be a great reminder for taking pills, there are also dose reminder apps available. Read more
Yes: Tamoxifen is most commonly prescribed for the treatment of hormone (+) breast cancer. While tamoxifen may cause birth defects during pregnancy, it actually can increase ovulation, thus increasing fertility. Accordingly, premenopausal women taking tamoxifen for breast cancer treatment must use (nonhormonal forms of) birth control. Read moreSee 1 more doctor answer
Tons: The common ones are bone pain; constipation; coughing; hot flashes; muscle pain; nausea; tiredness; vaginal discharge; weight loss. Severe ones are even a more comprehensive list - allergic reactions, vaginal bleeding, chest pain, coughing up blood, dark urine, decreased libido and so. ... On. Read moreSee 1 more doctor answer
Speak to your doctor: This is not the usual regimen for tamoxifen. It is usually recommended for daily use and intake for the best effect. Was this recommended by your doctor? If so, you need to find out why this deviates from the standard recommendation. If you are making up your own regimen, please do not proceed until you speak with your physician. Read more
Menopausal symptoms: The most common side effects of tamoxifen include hot flashes, changes in menstrual period, vaginal dryness, headaches, fatigue, and GI upset. Less common but more serious side effects include blood clots, strokes, uterine cancer, and cataracts. Read moreSee 1 more doctor answer
Maybe: Most clinical data has shown benefit of tamoxifen (tam) increasing up to five years. After 5 years it seems to level or possibly even worsen. There may be some cancer cells that not only become resistant but to which tam begins to act as an agonist. That being said there are still the ongoing atlas and atom trials that are trying to get more definite. Another option is ais after 5yrs of tam. Read moreSee 1 more doctor answer
Side effects: Tamoxifen is often used after treatment for breast cancer to help reduce recurrence. It is very helpful and should be taken if needed and recommended. However it is not w/o side effects which can include increased risk of blood clots, hot flashes, thinning of the bones (osteoporosis) and endometrial hyperplasia/cancer so if you are concerned d/w dr the risk and benefits as pertains to you. Read more
Talk with your doc: There are means for dealing with menopausal symptoms/hot flashes. Soy use is controversial but some antidepressants can help but be careful as some also inhibit tamoxifen metabolism. Effexor/venlefaxine is the most studied and does not do this. There are some patients who have achieved great relief with alternative therapies such as accupuncture. Read moreSee 1 more doctor answer
Nolvadex (tamoxifen): Sorry, only by prescription, assuming u care about the quality of the medication. Read more
Unclear: There is very little hard data about sage extract. The online advertisers say that sage is a mild estrogen type extract that helps menopausal symptoms. I am not sure if that claim has been validated. Tamoxifen works by blocking the body's estrogen and "starving" the tumor. If sage actually does work, then it would get in the way of tamoxifen's intended effect. Read moreSee 1 more doctor answer
No: There have been many studies that have compared tamoxifen to placebo, demonstrating it's effectiveness treating breast cancer; none of these studies, to my knowledge, ever showed any difference between tamoxifen and placebo regarding weight gain. Nevertheless, as many as 10% of women on tamoxifen do report weight gain. This may be due to post-chemotherapy effects or menopause, as well. Read moreSee 1 more doctor answer
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