Top
30
Doctor insights on: Is Sickle Cell Anemia Dominant Or Recessive Trait

Share
1

1
Is sickle-cell anemia a recessive, sex-linked trait?

Is sickle-cell anemia a recessive, sex-linked trait?

Yes and no: Sickle cell disease is recessive; you need to inherit a sickle gene from both parents to get the disease. It is not x-linked, however; if it were it would affect only boys. Boys and girls are equally affected by sickle cell disease. ...Read more

Dr. James Ball
356 Doctors shared insights

Sickle Cell Disease (Definition)

A group of disorders that cause red blood cells to become ...Read more


2

2
Describe symptoms of sickle cell anemia trait?

Describe symptoms of sickle cell anemia trait?

Usually none.: Patients with sca trait usually have no symptoms. If they are in an environment where oxygen is low, like high altitude, it is possible to have a pain crisis like sca patients get, but it is quite rare. ...Read more

3

3
I have sickle cell anemia trait can that affect me?

I have sickle cell anemia trait can that affect me?

Usually not: Sickle cell trait is a hemoglobin genotype as and is generally regarded as a benign condition. However, individuals with sickle cell trait may have rare complications that mimic sickle cell disease. ...Read more

5

5
I have the sickle cell anemia trait. What are the cons it can have on me now and in the future?

I have the sickle cell anemia trait. What are the cons it can have on me now and in the future?

Very few problems: The vast majority of the time sickle trait is clinically silent, meaning you will experience no health issues due to its presence. Rarely persons with sickle trait can experience sickling if they get dehydrated or exercise vigorously at high altitude. The major issue is understanding how sickle cell disease is inherited and your risk of having a child with this depending on mom's carrier state. ...Read more

6

6
If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more

9

9
If I have sickle cell trait is it possible to now be sickle cell anemia?

Confusing question: SS disease requires the genes for sickle cell from both parents, while S trait has it from one. You cannot change the genetic makeup that you were born with. Someone with trait can have a kid with SS if the partner has trait or SS. ...Read more

10

10
Can someons parents have sickle cell anemia and then they don't get the trait nor the anemia?

Another possibility: One sickle cell syndrome is a combination of sickle cell trait and beta thalassemia. The symptoms are most like sickle cell disease. If this person had children, they could pass on the beta thalassemia and not the sickle cell. Otherwise, people sickle cell disease will have children with either trait or disease. ...Read more

11

11
What type of genetic disorder is sickle cell anemia or trait?

Hemoglobinopathy: Patients with sickle cell anemia make an abnormal hemoglobin (hgb.). Normal HGB consists of paired protein chains (globin) and an iron containing part (heme). Patients with ssa inherit an abnormal beta-globin gene from each parent. Carriers have one normal beta-globin gene and one sickle beta globin gene. The carriers (trait) have no symptoms. ...Read more

12

12
If a child has sickle cell anemia, wouldn't both the parents need to have sickle cell trait?

If a child has sickle cell anemia, wouldn't both the parents need to have sickle cell trait?

No: There are varying forms of sickling diseases, however it is a recessive trait and so the parents may appear fine but carry the trait and yet have a child with the disease. ...Read more

13

13
Could both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Could both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Yes: Sickle cell anemia requires the gene from both parents to cause ss anemia. If only one parent gave the gene, the kid would be a trait carrier. ...Read more

15

15
Do one or both parents have to have sickle cell anemia in order for this trait to pass on to their children?

Do one or both parents have to have sickle cell anemia in order for this trait to pass on to their children?

No.: The parents could both be carriers of the sickle cell mutation on one of their two beta globin genes. Their other gene could be normal. This condition is called sickle cell trait. These people are usually asymptomatic with normal red cell indices. The child could have two copies of the mutant beta globin gene, one from each parent. Their is a 25% chance of this. For more details, consult your dr. ...Read more

16

16
Do both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Do both parents have to have the sickle cell trait for the child to have sickle cell anemia?

No: 2 abnormal (sickle cell) gene have to be inherited to have sickle cell disease. This can happen if both patents have sickle cell trait, one parent has sickle cell disease or both have sickle cell disease. ...Read more

17

17
If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

Nothing: Unfortunately, there would be 25% chance for your child to have sickle cell disease and 50% chance for sickle cell trait. With our technology now, nothing can alter the risk. Sorry to say, the only thing for somebody with sickle cell trait to completely prevent any possibility of having a biological child with sickle cell disease is by having a child with somebody with normal hb. ...Read more

18

18
Blood test positive for sickle cell anemia doctor said she is not sure if it is the trait or the actual illness! What do I do next?

Blood test positive for sickle cell anemia doctor said she is not sure if it is the trait or the actual illness! What do I do next?

Depends: If your doctor did a sickledex that was positive, this might not distinguish between sickle trait and sickle cell disease. The next test is a hemoglobin electrophoresis. If this shows mainly HGB a with HGB s, this is sickle trait. If both a and s but more s, this is sickle/beta+ thalassemia. If only s, sickle cell disease or sickle/beta 0thalassemia. Your doctor can explain what these mean. ...Read more

19

19
Which brand of Whey Protein do you think is best for muscle gain in an individual who has Sickle Cell Anemia Trait?

Which brand of Whey Protein do you think is best for muscle gain in an individual who has Sickle Cell Anemia Trait?

Doesn't matter: Your muscles don't care what brand of protein you eat. Sickle cell trait doesn't affect muscle metabolism. Lean meat and fish are a much denser source of protein than any supplement. Good luck. ...Read more

20

20
Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?

Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?

NO: To simplify- providing that the father has a completely normal blood - (no other type of congenital/hereditary bood disorder-like thalasemia minor, hemoglobin c disease etc) - the baby will have 50% risk to have sickle cell trait-but the baby will not have sickle cell anemia. ...Read more

21

21
Can sickle cell anemia be developed over time?

No: Sickle cell disease occurs when you inherit sickle genes from both parents. The parents are usually unaffected because they have at least one normal gene that does the work for two. When you have 2 defective genes, the work is not done and you have sickle cell disease. You don't catch it like a germ or develop it as a reaction to something. ...Read more

22

22
How is living with sickle cell anemia/disease?

Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems whatsoever. ...Read more

23

23
Can sickle-cell anemia be detected from a test?

Can sickle-cell anemia be detected from a test?

Yes: Certain blood work - i.e. Cbc, and a hemoglobin electrophoresis, - would need to be done to establish a diagnosis of sickle cell anemia. ...Read more

24

24
Can you develop sickle cell anemia as an adult?

Can you develop sickle cell anemia as an adult?

Yes: You may not manifest sickle cell anemia until later in life. However, you don't develop or acquire sickle cell anemia at some point in life. It is genetic so you had it since birth. ...Read more

25

25
What can cause the symptoms of sickle cell anemia?

Anemia itself: Causes some symptoms. Sickle cells can decrease flow to organs and lead to bone pain and chest syndrome. ...Read more

26

26
What is the long-term outlook for sickle cell anemia?

Sickle cell future: As we better understand sickle cell disease, we hope to increase the quality of life for those affected by this disease. It is essential for those who have this disease to see a physician who specializes in sickle cell. For those with very severe disease, bone marrow transplantation may offer a cure. For others, screening and healthy lifestyle choices will help manage their disease. ...Read more

27

27
What parts of the body does sickle cell anemia effect?

What parts of the body does sickle cell anemia effect?

Everything: Pretty much everything. As the problem is on the red blood cell itself and red blood cells are circulating through out the whole body and every organ systems in the body. It will definitely affect the bone marrow, the blood system, as well as other organs like kidney, lung, vasculature, brain, heart etc. ...Read more

28

28
Can you explain a punnet square of sickle cell anemia?

In 400 words?: This sounds like homework.
This is simple mendelian genetics, the old 1:2:1 ratio of outcomes if two carriers mate. So if two sickle carriers mate, 1/4 offspring will be wild-type, 2/4 will be carriers, and 1/4 will have full-blown sickle cell disease.
http://www. Ndsu. Edu/pubweb/~mcclean/plsc431/mendel/mendel1.htm. ...Read more

30

30
Why is sickle cell anemia so painful? I need some advice.

Why is sickle cell anemia so painful? I need some advice.

More info needed: Sickle cell disease is so painful because the sickled cells criss cross in the tiny blood vessels and decrease blood flow to areas downstream of the vessel. This causes pain because new oxygen and nutrients cannot be delivered and cell waste and co2 cannot be efficiently handled. As a 38 year old with sickle cell disease, you must have had excellent care and recommendations by your doctors. ...Read more

Dr. Steven Ginsberg
1,285 Doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more