Doctor insights on:
Is Sickle Cell Anemia Dominant Or Recessive Trait
Very few problems: The vast majority of the time sickle trait is clinically silent, meaning you will experience no health issues due to its presence. Rarely persons with sickle trait can experience sickling if they get dehydrated or exercise vigorously at high altitude. The major issue is understanding how sickle cell disease is inherited and your risk of having a child with this depending on mom's carrier state. ...Read more
If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?
No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more
Can you grow into sickle cell anemia? If you have the trait can you have it wen your younger but it doesn't show until it gets older?
What it the probability that a couple's child will be afflicted with sickle cell anemia if they both carry that trait but don't exhibit it?
Another possibility: One sickle cell syndrome is a combination of sickle cell trait and beta thalassemia. The symptoms are most like sickle cell disease. If this person had children, they could pass on the beta thalassemia and not the sickle cell. Otherwise, people sickle cell disease will have children with either trait or disease. ...Read more
Hemoglobinopathy: Patients with sickle cell anemia make an abnormal hemoglobin (hgb.). Normal HGB consists of paired protein chains (globin) and an iron containing part (heme). Patients with ssa inherit an abnormal beta-globin gene from each parent. Carriers have one normal beta-globin gene and one sickle beta globin gene. The carriers (trait) have no symptoms. ...Read more
Yes: Or one with trait and one with ss. ...Read more
Do one or both parents have to have sickle cell anemia in order for this trait to pass on to their children?
No.: The parents could both be carriers of the sickle cell mutation on one of their two beta globin genes. Their other gene could be normal. This condition is called sickle cell trait. These people are usually asymptomatic with normal red cell indices. The child could have two copies of the mutant beta globin gene, one from each parent. Their is a 25% chance of this. For more details, consult your dr. ...Read more
If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?
Nothing: Unfortunately, there would be 25% chance for your child to have sickle cell disease and 50% chance for sickle cell trait. With our technology now, nothing can alter the risk. Sorry to say, the only thing for somebody with sickle cell trait to completely prevent any possibility of having a biological child with sickle cell disease is by having a child with somebody with normal hb. ...Read more
Blood test positive for sickle cell anemia doctor said she is not sure if it is the trait or the actual illness! What do I do next?
Depends: If your doctor did a sickledex that was positive, this might not distinguish between sickle trait and sickle cell disease. The next test is a hemoglobin electrophoresis. If this shows mainly HGB a with HGB s, this is sickle trait. If both a and s but more s, this is sickle/beta+ thalassemia. If only s, sickle cell disease or sickle/beta 0thalassemia. Your doctor can explain what these mean. ...Read more
Which brand of Whey Protein do you think is best for muscle gain in an individual who has Sickle Cell Anemia Trait?
Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?
No: Sickle cell disease occurs when you inherit sickle genes from both parents. The parents are usually unaffected because they have at least one normal gene that does the work for two. When you have 2 defective genes, the work is not done and you have sickle cell disease. You don't catch it like a germ or develop it as a reaction to something. ...Read more
Sickle cell future: As we better understand sickle cell disease, we hope to increase the quality of life for those affected by this disease. It is essential for those who have this disease to see a physician who specializes in sickle cell. For those with very severe disease, bone marrow transplantation may offer a cure. For others, screening and healthy lifestyle choices will help manage their disease. ...Read more
Everything: Pretty much everything. As the problem is on the red blood cell itself and red blood cells are circulating through out the whole body and every organ systems in the body. It will definitely affect the bone marrow, the blood system, as well as other organs like kidney, lung, vasculature, brain, heart etc. ...Read more
In 400 words?:
This sounds like homework.
This is simple mendelian genetics, the old 1:2:1 ratio of outcomes if two carriers mate. So if two sickle carriers mate, 1/4 offspring will be wild-type, 2/4 will be carriers, and 1/4 will have full-blown sickle cell disease.
http://www. Ndsu. Edu/pubweb/~mcclean/plsc431/mendel/mendel1.htm. ...Read more
More info needed: Sickle cell disease is so painful because the sickled cells criss cross in the tiny blood vessels and decrease blood flow to areas downstream of the vessel. This causes pain because new oxygen and nutrients cannot be delivered and cell waste and co2 cannot be efficiently handled. As a 38 year old with sickle cell disease, you must have had excellent care and recommendations by your doctors. ...Read more