Doctor insights on:
Is Sarcoma Cancer Deadly
We are all scared of the word "cancer " is there any thing we can do at home, and is it deadly? Thank you, my mother was just diagnosed with sarcoma
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
It used to be seen: In elderly men of mediterranean origin, a purple raised lesions most commonly on extremities, and it was quite rare. However, it became the hallmark skin finding in the early aids epidemic, as immune systems deteriorated, these lesion occurred all over bodies. Interestingly, as immune systems recovered, many of these lesion involute indicating a strong importance of immunity. ...Read more
Derivation: Sarcomas arise from supportive tissues of the body. They are found in and derived from muscle, fibrous tissue and fascia, fat, nerve, blood vessel and bone. Spread is to liver and lung. Carcinomas arise from secretory and epithelial membrane spreading first to regional nodes as seen with breast, colon and lung. They respond differently to chemo. ...Read more
No: Chemotherapy does not make sarcoma worse. However, some kinds of sarcomas are quite resistant to many chemotherapies. Other types like ewing's sarcoma, osteosarcoma, rhabdomyosarcoma, and even synovial sarcoma can respond to chemotherapy very well and chemo is an essential part of the the cure of these diseases. There are also new drugs available that can slow the growth of more resistant types. ...Read more
Ewing sarcoma: Ewing sarcoma is a very treatable bone and soft tissue sarcoma that generally affects adolescents and young adults. The positive news is that in its localized (non-metastatic) setting it is very treatable and curable (about 70% survival) with appropriate chemotherapy, surgery and/or radiation therapy. In its metastatic stage, ewing sarcoma is more difficult to treat and the prognosis is poor. ...Read more
No.: Sarcomas of bone (osteosarcoma, ewing's etc.) are almost incurable without chemotherapy and have a very good chance of cure with chemotherapy. It is not clear if chemotherapy helps for soft tissue sarcomas, though. In some studies it helps, in others it doesn't, but it certainly doesn't make things worse. Each situation is different, so ask your oncologist. ...Read more
Usually random: Sarcomas are bone and soft tissue cancers. Generally, these occur because of random events in most patients. However things like radiation exposure can increase the risk of bone and soft tissue sarcomas particularly with higher dose radiation like used for treatment of other cancers. There are some genetic diseases like li-fraumeni that can result in getting a sarcoma and other cancers. ...Read more
Yes they are: Sarcomas are embryo logically mesodermal tumors like muscle bones, supporting tissue etc, if they are not detected early and not treated they are just as bad as carcinomas, . They tend to spread by blood stream not by lymphatics, usually resistant to radiation. ...Read more
Terminology: Forget the arcana of germ layers in cancer nomenclature. Sarcomas are cancers that have, for their cell of origin, a connective tissue cell -- bone, cartilage, undifferented mesenchyme, fat, smooth / striated muscle, endothelium. By convention, cancers arising from blood elements, lymphocytes and mesothelium are given non-sarcoma names. ...Read more
Yes. It is a: Disease affecting young men, "always" under 30, teens most common, tending to arise in bones, and metastases to other bones and lung. When caught in the originating bone, usually with pain, or even fracture, before metastasis, it can be cured. Once metastatic, cure is not likely. Ergo, it can be fatal. ...Read more
Very: It will invariably kill if it is untreated. If it has spread to the lungs, we presently have no cure. If it has not, with today's therapy (surgery; the value of radiation and/or chemotherapy, depending on the stage of tumor and type of treatment) more than 50% of patients survive 5-years, the majority of these disease-free. Good luck. ...Read more
Variable: Most patients with soft tissue sarcomas can be cured and have a normal life span. Even in cases where sarcoma had spread, cure can sometimes be achieved. In cases where it cannot be cured, patients may live from weeks to years. It depends on the sarcoma type and the patient. Nobody can predict survival of any one patient. We only know statistics for large groups. ...Read more
Can be: A rare form of cancer which usually occurs near to the joints of the arm, neck or leg. Synovial sarcoma occurs most commonly in the young, representing about 8% of all soft tissue sarcomas. Primary treatment for synovial sarcoma is surgery to remove the entire tumor with clear margins when possible. Treatment can involve chemotherapy and radiation. Localized disease has about 70% five year survial. ...Read more
Possibility: Neurofibrosarcomas have a genetic basis with a possible abnormality in chromosome 17. Fifty percent of these tumors are associated with a familial condition known as neurofibromatosis, which causes tumors of nerve support cells (including Schwann cells). Resection of the tumor after possible shrinking is a consideration. The sarcomas in general tend not to respond well to chemo. Rather RT post op in the larger lesion is a consideration. ...Read more
Found out I have a rare cancer called neurofibroma sarcoma. What are the chances my kids can get it?
A possibility: Neurofibrosarcomas are peripheral nerve malignant lesions with a tendency to metastasize. They can occur in young children and are frequently associated with café-au-lait spots on the skin. There is a congenital form of disease, von Recklinghausens, where diffuse benign cutaneous neurofibromas are found and which have a high conversion rate to malignancy. Such tumors do occur on extremities. ...Read more
My father was diagnosed Sarcoma dedifferentiate. Being his son I'm have more chance to get this kind of cancer.?
My dad had sarcoma the year I was conceived in 82 am I at any risk of developing cancer. He lived 11 years with it.
No: The vast majority of sarcomas are sporadic. If his family did not have several uncommon cancers in young people, there is no cause for concern. ...Read more
Sometimes: Sarcomas cover a large group of tumors that arise from soft tissues (skeletal muscle, smooth muscle, bone, cartilage, blood vessels, nerves, fat, connective tissue). Just below the skin, all of these structures can become malignant and give rise to a sarcoma. A biopsy with microscopic examination (by a pathologist) is required, with special studies usually required to confirm the diagnosis. ...Read more
Combo chemo/surgery.: Systemic chemotherapy with doxorubicin, ifosfamide, etoposide, and vincristine is effective and done before limb saving surgery. Peripheral primary lesions (below the elbow and mid-calf) can have a 5 year survival of 80%. Even metatstatic disease has a 25-40% cure rate with high dose therapy and stem cell transplant. ...Read more
No: I know no syndrome in which the two run together, but if they did both occur at a young age in the same person, I would suspect one of the cancer family syndromes such as li fraumeni. If there was otherwise a strong family history, or the person wished to make a decision about parenthood, then a talk with a geneticist would be in order. ...Read more
Do all cancers have a maintenance program that goes with it after finishing chemotherapy? Specifically, cancers like ewing's sarcoma and osteosarcoma?
Maintenance....: Is not typical in cancer rx, particularly not for solid tumors like ews or osteosarcoma. Yet, a prolonged period of surveillance is needed after completing rx. Surveillance is needed to address late effects of therapy and to monitor for disease recurrence. Maintenance has a prominent and essential role in all, and may become a part of rx for other cancers as we learn more of molecular pathogenesis. ...Read more
I would just like to know if I had sarcoma (bone cancer), it is now "gone" what would be the chances of getting any type of cancer again? And what cancers that could be?
Treatable: Not too long ago osteogenic sarcoma used to be almost uniformly fatal. But with chemotherapy regimens now available, the majority of patients can be cured. Surgery is also required and in most cases the tumor can be removed while keeping the limb. While it is a very serious cancer, we now have very good treatment options available. ...Read more
My sister was diagnosed with bone cancer (osteogenic sarcoma). What can you tell me about this kind of cancer?
In order 2 answer-: -this an orthopedic surgeon has 2 B blunt. First of all B sure she is Cing an ortho oncologist who deals with bone Ca. The outlook is grim especially if it is located closer 2 the body, a distal tibia is better than in the prox femur. Cures R rare, but with no metastatic disease & eary amputation, U have the best chance 4 more time 2 live. By time Dx is made, spread is usually all ready present. ...Read more
By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more