Doctor insights on:
Is Sarcoidosis A Genetic Disease Will My Children Get It
Family sarcoid: It is not likely that you would give your children sarcoid, however your inherited immune system may make it more likely. The statistics show about a 16%increase of sarcoid in family. Sarcoid has an unknown cause.Some ideas have been, bacteria in the environment-but scientists have not isolated it; or chemicals in the environment-more common on rural areas, fields/ farmers, health care, & teachers. ...Read moreSee 2 more doctor answers
A genetic disease is a disease that is caused by a defect in the genetic (dna) material in a gene(s). It can be inherited and mosy pose a risk to other family members and/or to future children. For many genetic diseases there are molecular tests that allow detection of a change(s) called mutations, we can also detect deltions or other changes to the gene's dna that can also result ...Read more
Where did tay-sach originated from? From what organism or plant do people get this disease? I know this is a genetic disease but how did it become a genetic disease?
Human : Human genetic diseases arise because of mutations in the genetic information carried in the reproductive cells (eggs and sperm or the cells that make them). Genetic information is stored in the complex molecule called dna, which has properties that allow it to be copied, kind of like the way a computer disk can be copied. Dna contains information packed into functional units called genes, which behave like individual computer programs, and often create proteins that contribute to the machinery of the cells that make up our bodies. Just like the way the information on a computer disk can become corrupted when it is stored over time (imagine a cd or dvd exposed to sun, scratches, or dust) or when it is being copied, the information stored in dna can be corrupted either when stored or when copied. This is called a mutation. Some mutations can produce machinery that doesn't work at all, and some mutations produce machinery with properties that are different than those of the original gene. Tay sachs disease (also called hexosaminidase a deficiency) is caused by a mutation in the hexa gene that makes the machine (or enzyme) called hexosaminidase a. When it is not mutated, this enzyme helps to break down complicated sugar-like molecules in human cells. The mutation that causes tay sachs disease makes a non-working enzyme. The sugar-like molecules build up in cells, and lead to serious problems. (children with tay sachs disease may die by the age of 4.) every human cell has two copies of just about every gene. One copy is from the father, and one copy is from the mother. If you get a mutated hexa gene from one parent, and a normal hexa gene from the other parent, the normal gene will make working hexosasminidase a, and you will be able to break down those sugars... So you won't die... So you may live to pass your genes on to your children. When parent passes on genes to a child, only one of the two copies is passed. (if this didn't happen, then each generation would have twice as many genes as their parents.) so, a parent with one good copy and one bad copy of a gene, has about a 50:50 chance of passing the bad gene on to a child. To get tay sachs disease, a child has to get two bad copies of the hexa gene. One from each parent. ...Read moreSee 1 more doctor answer
How do people get anorexia? Is it a genetic disease? If you want to be anorexic and act as one would, will you become anorexic?
Anorexia nervosa: Excuse me -- why would you want a deadly illness? Anorexia nervosa does show genetic transmission; it is not complete, but studies with twins show that it's highly heritable. Others can develop it too, but people with this illness suffer and cause their families and significant others suffering too. Please consult a psychiatrist about your desire for self-harm. ...Read moreSee 1 more doctor answer
Tuberous Sclerosis: Tuberous sclerosis is often called ts or tsc. It is a hereditary disorder that is characterized by individuals devoloping a small benign lesion called a hamartoma in various organs including the brain, lung and kidneys. Ts fact sheet from nih at http://www.Ninds.Nih.Gov/disorders/tuberous_sclerosis/detail_tuberous_sclerosis.Htm. ...Read more
Unknown: Some are rarer than one in 100,000. Is continually finding new genetic disordersand we may have no clue with regard to how frequent they are. There are dozens of severe multiple malformation syndromes which are striking but none of the worlds geneticists have a clue with regard to what causes them.how do you estimate a single case in the world's medical literature? ...Read more
It's quite possible: We often think of genetic disease as causing birth defects or problems with early childhood development, but in fact genetic conditions can become apparent at any age. Take hereditary cancer, for instance. That often is not apparent until adulthood, often among young adults. But the real answer is that everything about our illness and wellness has a genetic component, often small, sometimes big. ...Read more
Narrow it: The more narrow the subject, the more interesting the outcome. Get a few current papers from the big journals like NEJM or Science or Nature: Genetics. Further, if your grader has some particular ideological point of view (perhaps "It is morally wrong to end pregnancies even when the unborn child has a terrible genetic disease"), don't take an opposite position. Keep it interesting. ...Read more
No: In some cases of genetic disorders there is a founder effect such that a certain genetic disorder runs within that ethnic backround. An example is ashkenazi jewish heritage is associated with a number of disorders like tay-sachs. Although variable based on the condition, spontaneous mutations occur in individuals such that they are affected but are not related to an affected person. ...Read more
Inheritance: A genetic disease is inherited in one shape or form from parents. They can be dominant, meaning that if you get the gene from one parent you have the disease. Usually in this case the parent also has the disease. They can be recessive, meaning you need to get the gene from both parents. Usually in this case both parents are unaffected carriers. Non-genetic diseases are seemingly random. ...Read more
See below: Basically, bad luck.Get a more detailed answer ›
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more