Doctor insights on:
Is Pvl Reversible In Any Way
Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest ...Read more
No: Periventricular leukomalacia (pvl) is a form of white-matter brain injury, characterized by the necrosis of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder. At 4 y/age child might have consequences related to pvl, such as cerebral palsy. There is no certain prevention known at this point. ...Read moreSee 1 more doctor answer
IVH/PVH: Premature babies born at < 32 weeks gestation are at risk for periventricular hemorrhage (ivh/pvh). Later the pvh turns into pvh (periventricular leukomalacia). There are some precautions that the neonatologists can take to lower the risk of pvh in these babies but they cannot abolish the risk. Neonates who develop high grade of ivh/pvh (generally grade iii or iv) develop pvl. ...Read moreSee 2 more doctor answers
Cerebral palsy: Ivh occurs in prematures, then resolves. Pvl is the result of changes in the brain due to prematurity. Cerebral palsy is a clinical diagnosis which includes spasticity and the ability to elicit clonus. This is often the result of events associated with prematurity. Clonus is a clinical finding that can be seen in normal children, but is more common in children with cerebral palsy. ...Read moreSee 2 more doctor answers
Small: Pvl is more common in premature than term infants, and occurs more frequently with decreasing gestational age and size. Study showed the incidence of pvl is ~ 3-4% of infants who weigh < 1, 500 g (3.3 lb) have pvl, and 4-10% of those born < 33 weeks of gestation (but who survive more than three days postpartum). Another suggest <32 weeks account for~2% of all live births in usa. ...Read moreSee 1 more doctor answer
A problem...: Pvl as defined above is an type of brain injury that occurs in infants; the tissues surrounding the "ventricles"(which house fluid) are damaged leading to 'holes'. The problem arises in that there is no curative treatment for this disorder as of today; treatment focuses on helping the baby/child cope with the developmental and neurological consequences of the disorder in the first 2 years of life. ...Read moreSee 1 more doctor answer
Yes: Periventricular leukomalacia, or pvl, occurs when cortical brain tissue (white matter) is lost. It may be associated with damage to deeper brain structures (grey matter). Since pvl means loss of brain tissue, there will be permanent effects on certain motor (movement), and occasionally cognitive (thinking) abilities, often referred to a cerebral palsy. The degree of impairment is highly variable. ...Read moreSee 1 more doctor answer
Good peds OT and PT: Kids with pvl are at greater risk for cerebral palsy among other neuromuscular disorders. There is excellent rehab for kids with pvl, and most of them involve repetitive movement and relearning how to make normal movements, recruiting more brain to enable the movement to happen. Good pt and ot will help with that, and most major centers have them. The local support groups will know the good names. ...Read moreSee 2 more doctor answers
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