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Doctor insights on: Is Primary Sclerosing Cholangitis Painful

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Dr. Cornelius O'Leary Jr
32 doctors shared insights

Primary Sclerosing Cholangitis (Definition)

Primary sclerosing cholangitis (psc) is a chronic liver disease caused by progressive inflammation and scarring of the bile ducts of the liver. The inflammation impedes the flow of bile to the gut, which can ultimately lead to liver cirrhosis, liver failure and liver cancer. The underlying cause of the inflammation is ...Read more


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Is primary sclerosing cholangitis rare?

Is primary sclerosing cholangitis rare?

Yes: The goal of managing acute attacks is antibiotics and IV fluids. In about 15%, emergency decompression or surgery is needed. Prevention of future attacks of cholangitis is based on removing biliary stones and debris, dilation or resection of strictures, and establishing optimal biliary drainage. Also important to rule out the clonorchis parasite. Your GI doctor can discuss newest treatments. ...Read more

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How can I treat primary sclerosing cholangitis?

How can I treat primary sclerosing cholangitis?

Difficult problem: Psc: autoimmune swelling/scarring of bile ducts within and outside the liver; often associated with infl. Bowel (usually ulc colitis). Increased risk for biliary ca. Med rx for itch, biochem abnormalities, e.g. Urso (bear bile), antihistamines, antibiotics for infections, vitamin supllements for deficiencies. Ercp procedure may open some strictures (narrowing). Ultimately, may need liver transpla. ...Read more

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Primary sclerosing cholangitis, what is this like??

Bile duct obstructio: Idiopathic (probably autoimmune) progressive scarring and narrowing of the bile ducts. May need surgical intervention or transplant This reference may help: http://www.mayoclinic.org/diseases-conditions/primary-sclerosing-cholangitis/basics/definition/CON-20029446 ...Read more

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Could you explain what is primary sclerosing cholangitis?

Bile duct scarring: Primary sclerosing cholangitis (psc) is an inflammatory disease of the bile ducts that causes scarring and subsequent obstruction of bile ducts inside and/or outside the liver. This blocks the flow of bile to the gut, which can ultimately lead to cirrhosis of the liver. The underlying cause of psc is not entirely known, but believed to be an auto-immune disorder with a strong association with uc. ...Read more

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Primary sclerosing cholangitis - what is the inherited risk?

Very low: PSC is most commonly seen in patients with ulcerative colitis. Patients with PSC have 60-72% association with ulcerative colitis; low genetic and immunologic factors are attributed to PSC. ...Read more

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Does primary sclerosing cholangitis usually cause many symptoms?

Does primary sclerosing cholangitis usually cause many symptoms?

It can.: Primary sclerosing cholangitis (= psc, inflammation of bile ducts) can give symptoms such as itching, pain in the right upper abdomen, fevers, chills, night sweats, and jaundice (yellow skin, yellow whites of the eyes). Most people with this illness have ulcerative colitis, which has symptoms of its own (eg. Bloody diarrhea, abdominal pain). Many with psc eventually need liver transplant. ...Read more

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What is the definition or description of: primary sclerosing cholangitis?

What is the definition or description of: primary sclerosing cholangitis?

PSC: Primary sclerosing cholangitis (psc) is a chronic liver disease caused by progressive inflammation and scarring of the bile ducts of the liver. The inflammation impedes the flow of bile to the gut, which can ultimately lead to liver cirrhosis, liver failure and liver cancer. The underlying cause of the inflammation is believed to be autoimmunity. ...Read more

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Dr. Corey Clay
69 doctors shared insights

Cholangitis (Definition)

It is an infection of the bile ducts. Usually there is an obstruction of the bile ducts. Most commonly this is caused by a gallstone, although there are other rarer causes. It can be life threatening. If you have pain in your right upper quadrant, a fever and are jaundiced, ...Read more


Dr. Daniel Saurborn
27 doctors shared insights

Sclerosing Cholangitis (Definition)

It is an inflammatory condition of the main bile duct that drains bile from the liver. It is important to follow with an experienced gastroenterologist because untreated, the condition can ...Read more