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Doctor insights on: Is Peptic Ulcer Disease Also Related To Having Pernicious Anemia

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Is peptic ulcer disease also related to having pernicious anemia?

Is peptic ulcer disease also related to having pernicious anemia?

Ulcer/infection: Vitamin B12 requires intrinsic factor secreted by the stomach in order to be absorbed. If enough of the stomach cells have been damaged by ulcers, a lack of intrinsic factor secretion could lead to a decreased absorption of B12 and pernicious anemia. Infection with helicobacter pylori can lead to chronic gastritis which can also lead to both ulcers and anemia. ...Read more

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Ulceration (Definition)

Exact synonym so far as this pathologist is concerned. An ulcer is a lesion on a body surface (outer or inner) in which the epithelium and at least some of the underlying connective tissue has been lost specifically to necrosis (cell death) rather than just mechanical or chemical injury. All ulcer craters ...Read more


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Can patients with peptic ulcer disease pud have pernicious anemia?

Can patients with peptic ulcer disease pud have pernicious anemia?

Hopefully not: If you are managed with chronic acid reducing medications, you run the risk of low B12 levels in your blood. Get tested and supplement if recommended. You should not experience B12 anemia if under medical care. ...Read more

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Is it possible for chronic gastritis to cause pernicious anemia?

Is it possible for chronic gastritis to cause pernicious anemia?

The two are linked: This finding goes back to 1964, believe it or not: http://www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc1552204/?Page=1 there are autoimmune antibodies in both conditions, so while one might not cause the other, the two are related. ...Read more

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Is cirrhosis related to pernicious anemia?

Is cirrhosis related to pernicious anemia?

No it is not!: Unless it is primary biliary cirrhosis, or autoimmune hepatitis. They are associated with true pernicious anemia. Alcoholic cirrhosis is not! ...Read more

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Help please! could celiac disease cause gastritis in stomach?

Help please! could celiac disease cause gastritis in stomach?

Possibly: I have seen many patients with celiac disease that have inflammation in other parts of their upper GI tract (i.e. esophagus or stomach). The key would be to start by going gluten free and see if symptoms resolve. If they do not, your doctor may consider another endoscopy to see how your stomach is doing. ...Read more

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What is reflux or Peptic disease?

What is reflux or Peptic disease?

Reflux: Reflux is when stomach contents- either acid or base, go into the esophagus. Continued irritation of the esophagus can lead to changes in the lining of the esophagus. People with reflux do well with small meals and not eating within three hours of bedtime. ...Read more

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Which causes IBS to be so different to Crohn's disease or coeliac, symptom wise?

Which causes IBS to be so different to Crohn's disease or coeliac, symptom wise?

Symptom wise: It is difficult. Both can cause diarrhea. In general a good history, lab tests and sometimes biopsies will tell you the diagnosis. If everything comes back normal, then you may try what is called an elimination diet and record which foods bother you more than others and you will be surprised how often people get better if they ear correctly. Best wishes. ...Read more

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Can stomach problems( h pyolri infection, pud or gasritis) cause loose stools? Or is this a sign of colon problems too ? :|

Can stomach problems( h pyolri infection, pud or gasritis) cause loose stools? Or is this a sign of colon problems too ? :|

Helicobacter pylori: This will seldom affect the nature of your stools. This is probably due to another issue. ...Read more

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Would having Gerd and celiac disease cause a patient to have high b12 levels?

Would having Gerd and celiac disease cause a patient to have high b12 levels?

No: In fact people taking PPI class of drug for GERD often end up with low serum B12 level which may or may not be clinically important. ...Read more

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Is it possible for eosinophilic esophagitis be a symptom of lupus or other autoimmune disease?

Is it possible for eosinophilic esophagitis be a symptom of lupus or other autoimmune disease?

Learning more : A recent publication in the journal of allergy and clinical immunology described a subset of patients with eosinophilic esophagitis who have connective tissue disease. Musculoskeletal pain and hypermobility of the joints were described in these patients. We hope to learn more and more is further research gives us more answers. ...Read more

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What is the best test to differentiate iron deficiency anemia from anemia of chronic disease?

What is the best test to differentiate iron deficiency anemia from anemia of chronic disease?

Ferritin: Ferritin measures the amount of iron storage in the body and usually is really low in iron deficiency anemia, contrary to anemia of chronic disease that usually shows a normal ferritin level. There are other parameters to take into account off course but this one is one of the best to differentiate. ...Read more

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Can iron anemia deficiency due to bleeding polyps affect your immune system? Can Chrohns, Intestinal inflammation, and GI issues cause low IG levels?

Can iron anemia deficiency due to bleeding polyps affect your immune system? Can Chrohns, Intestinal inflammation, and GI issues cause low IG levels?

No immune change: Very few situations can alter the immune system so that it is not functional. especially with bleeding polyps and iron deficiency anemia. Usually with malignancy causes problems not by eliminating the immune system but by temporarily blocking it. With Crohns and IBD there would be a tendency to respond by enhancing the immune IgG response as a means of defending against the inflammatory process ...Read more

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Can peptic ulcer disease lead to cancer?

Rarely: Peptic ulcers and stomach cancer are both caused, in part, by helicobacter infection. A stomach cancer may present as an ulcer. A bona fide peptic almost never turns into cancer. ...Read more

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Can gastritis , ulcers, or acid indigestion lead to cancer?

Can gastritis , ulcers, or acid indigestion lead to cancer?

Very rarely, yes: It is very uncommon but there are certain types of stomach inflammation that are potentially pre-cancerous. ...Read more

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Can iron deficiency anemia be a symptom of another problem?

Can iron deficiency anemia be a symptom of another problem?

Yes, absolutely: Iron deficiency anemia can result from chronic blood loss in the body. The source must be found and treated. It can be an occult tumor in the colon, or excessive menstrual bleeding too. Poor diet or absorption can be responsible too. Other possible sources as well. ...Read more

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Dr. Scott Bolhack
2,089 doctors shared insights

Ulcer (Definition)

An ulcer is a discontinuity or a break in a body membrane that impedes the normal functioning of the organ of which that membrane is a part. Ulcers are further classified by their location. Ulcers are usually caused by infections, excessive acid production, stress, ...Read more


Dr. Sidney Vinson
733 doctors shared insights

Peptic Ulcer (Definition)

A condition in which there is corrosion of the surface of the stomach and/or first part of the small intestine. Symptoms include upper abdominal pain, nausea, ...Read more