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Doctor insights on: Is Peptic Ulcer Disease Also Related To Having Pernicious Anemia

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Is peptic ulcer disease also related to having pernicious anemia?

Is peptic ulcer disease also related to having pernicious anemia?

Ulcer/infection: Vitamin B12 requires intrinsic factor secreted by the stomach in order to be absorbed. If enough of the stomach cells have been damaged by ulcers, a lack of intrinsic factor secretion could lead to a decreased absorption of B12 and pernicious anemia. Infection with helicobacter pylori can lead to chronic gastritis which can also lead to both ulcers and anemia. ...Read more

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Pernicious Anemia (Definition)

It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily ...Read more


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Can patients with peptic ulcer disease pud have pernicious anemia?

Can patients with peptic ulcer disease pud have pernicious anemia?

Hopefully not: If you are managed with chronic acid reducing medications, you run the risk of low B12 levels in your blood. Get tested and supplement if recommended. You should not experience B12 anemia if under medical care. ...Read more

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If they have a gastric ulcer or one in the duodenum, can they have pernicious anemia due to the stomach of duodenum being destroyed somewhere?

Possibly.: Pa is associated with antibodies that attack cells in the stomach. Besides interfering with B12 absorption, the stomach can develop atrophic gastritis, an inflammation of the stomach that results in the loss of all glandular tissue and scarring of the stomach. But ulcers are not a sign of this, and definitely not duodenal ulcers. The B12 problems come first, other stomach issues later. ...Read more

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Wondering why pernicious anemia patient having opthous ulcer?

Wondering why pernicious anemia patient having opthous ulcer?

B-12: Pernicious anemia is a type of anemia caused by vitamin b-12 deficiency. Vitamin b-12 is necessary for the normal maturation of red blood cells but also other types of cells in the body including those of the oral mucosa, where lack of normal maturation leads to various mucosal lesions from flattening of the taste buds to aphthous ulcers. ...Read more

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I had a peptic ulcer and now i have anemia what should i do and eat to increase red blood cells and i also have G6PD deficiency ?

I had a peptic ulcer and now i have anemia what should i do and eat to increase red blood cells and i also have G6PD deficiency ?

Test for H pylori, +: H pylori bacteria are a common cause of peptic ulcers.A 2-week treatment can get rid of it, and eliminate recurrence. Gastric bleeds will give heme positive stools. But the anemia may be from hemolysis caused by exposure to something which causes acute hemolysis (busting open of your fragile red cell membranes) in G6PD deficiency. Serum free hemoglobin will be high. Learn what you must avoid! ...Read more

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If MCV is enlarged, b12 and vit D rock bottom but no cealac disease could this mean pernicious anemia? HB 116, ferritan is 86 and low stomach acid

If MCV is enlarged, b12 and vit D rock bottom but no cealac disease could this mean pernicious anemia? HB 116, ferritan is 86 and low stomach acid

Oral supplement: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you may try oral supplements of B12, vitamin D3, iron and multivitamins first. If that does not resolve high MCV, you may need B12 injections. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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I have Graves' disease, vitiligo and pernicious anemia. What is the best diet to follow in order to prevent any more autoimmune diseases? Sandy.

I have Graves' disease, vitiligo and pernicious anemia. What is the best diet to follow in order to prevent any more autoimmune diseases? Sandy.

No great way: However I would consider getting your vitamin D3 level to the higher normal range since vitamin D3 is considered an immune regulator. I don't know if this would work but it would not likely cause any harm. The only way to find out is to get tested. Unfortunately, when you have one autoimmune problem you are more likely to have another presumably due to impaired immune regulation. ...Read more

Dr. Nicholas Karyotakis
555 doctors shared insights

Stomach Ulcer (Definition)

Stomach ulcers, also called peptic ulcers, are erosions in the wall of the stomach that can result in bleeding or pain. They can be caused by ibuprofen and similar medicines called non-steroidal anti-inflammatory drugs (NSAIDs), or by infection with a bacteria called H. pylori that ...Read more


Dr. Scott Bolhack
2,050 doctors shared insights

Ulcer (Definition)

An ulcer is a discontinuity or a break in a body membrane that impedes the normal functioning of the organ of which that membrane is a part. Ulcers are further classified by their location. Ulcers are usually caused by infections, excessive acid production, stress, ...Read more