Doctor insights on:
Is Parkinsons Disease Genetic And What Causes It
Parkinson's causes: Specific gene mutations play a role and genes changed due to environmental exposure may be causal. Having a close relative who has it increases your risk. The triggers are felt to be virus or toxins (herbicides or pesticides). Changes in the brain of parkinson patients include: lower dopamine, lower norepinephrine, and the presence of lewy bodies. ...Read more
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
BUT, Rx Available!!!: Dopamine meds are mainstay of treatment. Modern therapy recommends longer lasting, milder potency meds first: Azilect (mao-b selective inhibitor) & Dopamine agonists (requip xl/mirapex er/neupro). After they've been maximized & stronger meds are needed to adequately manage symptoms, then sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together) are begun. Tailor rx with side effects in mind for each person. ...Read moreSee 3 more doctor answers
Caused by abnl gene: Fh is caused by a gene mutation that leads to defective LDL (cholesterol) receptor so that the liver does not recognize chol is around and produces too much. It is monogenic ( single gene) because problem is in only 1 gene instead of multiple genes such as other disorder like diabetes. ...Read moreSee 1 more doctor answer
Yes and no: We know what happens, but not why. Very briefly, ulcerative colitis (uc) and crohn's are distinct but similar, and involve dysregulation of the immune system in the gut. There are certain genetic risks, but we don't know for sure why the process happens in some people but not others, so in that sense we don't know what directly causes them. See http://tinyurl.Com/6u8bb for more info. ...Read moreSee 1 more doctor answer
Cause is unknown: The true cause of buerger's disease is not known, but mostly diagnosed in male smokers age 40 or younger (becoming more common in women too). It is a rare disease affecting blood vessels of arms/legs--the inside becomes inflammed and narrowed at times blocking the blood flow thus killing the tissues as seen in picture here. Smoking is thus= biggest trigger. Stay smoke-free, kachita1. Good luck. ...Read more
No, thankfully!!: They only share a common word in the name. They are in no way related. Wpw is an electrical conduction defect in the heart. Parkinson's disease is a neurodegenerative disorder featuring physical symptoms such tremor of limbs at rest, slow movements & stiff (rigid) muscles causing quiet facial emotions, softer voice, bent forward head & neck posture, decreased arm swing, slow-shuffled walk, etc. ...Read moreSee 1 more doctor answer
What is annal fissure disease, Is this disease easily curable and what are its causes and treatment.
A tear at outlet: Anal fissure is incredibly common and is simply a tear of the lining of the anal outlet. The tear bleeds bright red blood and exposes the inner anal muscle which responds by going into spasm which causes pain. The tear is caused by straining. Treatment is to stay away from straining with stool softeners and fiber supplement and warm water or medication to treat muscle spasm like nifedipine ...Read moreSee 2 more doctor answers
Yes!!: Pd can definitely cause fatigue/malaise, even out-right excessive daytime sleepiness. These are purely organic symptoms of the disease. Also, slowed gut parastalsis can reduce appetite (loss of sense of smell & thereby taste contributes too) , cause early satiety (filling quickly), constipation & leave the person feeling gassy & bloated. All of which contribute to a sense slow metabolism. ...Read more
Mngie: MNGIE is a multi system autosomal recessive disorder characterized by gastrointestinal dysmotility and peripheral nervous system involvement death occurs before 35 years of life. Treatment options include allogeneic hematopoietic stem cell transplantation and carrier erythrocytes entrapped TP therapy . Hope this answers your question . Mitochondrial Neurogatrointestinal Encephalomyopathy ...Read more
Celiac disease: In Celiac disease the body reacts to gluten (in wheat and gluten like proteins in rye and barley) in the small intestine causing damage. This limits the intestine's ability to absorb some nutrients. Classically people have loose stool, bloating, and abdominal discomfort but more often are just found when screened for other reasons (like symptoms of a nutritional deficiency like iron or bone loss). ...Read moreSee 1 more doctor answer
See below: Previously termed "lou gehrig's disease", the process destroys motor nerve cells and leads to muscle atrophy weakness, swallowing and breathing difficulties. The sole approved drug is Riluzole which may delay tracheostomy. Treatment is basically symptomatic and supportive, but patients succumb nonetheless. There is no cure. ...Read more
Could coexist: There is no relationship with ms and dermatological conditions in general, but not unique for patients suffering psoriasis to later develop ms, or even the reverse. Here's the point, if you have ms, then avoid meds that affect tumor necrosis factor alpha, as the neurological problems can be adversely affected. ...Read moreSee 1 more doctor answer
Extremely rare one: Some people who suffer from depression are helped with drugs that increase the norepinephrine stores in nerve endings. Drugs such as Effexor (venlafaxine) or wellbutrin do this. Haveing a severe deficiency of these neurotransmitters is very rare and life threatening. http://www.ehow.com/way_6158789_norepinephrine-deficiency-drooling-treatment.html. ...Read more
No: They can be the same but not always. A genetic disorder is a condition with symptoms due to abnormal gene functioning due to genetic alteration of some type like gene deletion or mutation. If this genetic alteration is inherited from either parent then it is a hereditary condition. If the genetic alteration occurs spontaneously then someone can have a genetic disorder without it being hereditary. ...Read more
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