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Is Paraneoplastic Syndrome Hereditary
Depends: Paraneoplastic syndrome is a syndrome (constellation of symptoms of variable types) that occurs in association (para-) with cancer (-neoplastic). Some specialized testing can detect antibodies involved in paraneoplastic syndrome, but sometimes it is not detectable. The body parts effected depends on the type of syndrome but may involve the entire body -- eg myasthenia gravis and thymoma. ...Read moreSee 1 more doctor answer
Multiple symptoms: There are several paraneoplastic syndromes. Most are related to the production of excess hormones or tumor necrosis factor or high blood calcium. Neurologic processes can also occur. Your symptoms could be due to a lot of things, but don't sound like a specifric paraneoplastic syndrome to me. ...Read more
Tumor related: A paraneoplastic syndrome is a condition related to presence of a neoplastic growth but not to the local presence of cancer cells It is mediated by humoral factors expressed by the tumor or from an immune response against the tumor. They most commonly result from the cancers of the lung, breast, ovaries or lymphoma . Symptoms include difficulty in walking, swallowing,,and vewrtigo ...Read more
Cancer related hormo: Cancers like lung cancer can produce chemicals which have hormone like effects on the body. This can cause, for example the calcium level or blood counts to go up. These are called paraneoplastic syndromes, they usually go away once the tumor is removed or controlled with chemotherapy. ...Read more
Maybe: Some defined antibodies are associated with paraneoplastic syndromes (note: plural). In those cases the testing may be positive. However, a person could have a paraneoplastic syndrome with negative testing for the known paraneoplastic antibodies. It is possible that studies are being done to characterize tests for paraneoplastic syndromes. That might be experimental. ...Read moreSee 1 more doctor answer
Serum Ab: It is a clinical diagnosis. But detection of some well characterized paraneoplastic antibodies in serum or CSF can be helpful. For example, anti-hu (encephalomylitis/sclc), anti-yo (cerebellar degeneration/breast or gyn cancer), anti-calcium channel (lambert-eaton syndrome), etc. Of note, negative antibody does not exclude the diagnosis. ...Read more
Many: Neurologic paraneoplastic syndromes are caused by an abnormal immune response to the tumor, which makes the body accidentally attack its own nervous tissue. Muscle weakness, stiff limbs, dizziness, coordination problems, vision problems, confusion, difficulty swallowing, memory problems and numbness are some of the many possible symptoms. ...Read moreSee 1 more doctor answer
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