Top
20
Doctor insights on: Is Narcolepsy Known To Be A Genetic Disorder

Share
1

1
Is narcolepsy known to be a genetic disorder?

Is narcolepsy known to be a genetic disorder?

Yes and no: In dogs narcolepsy is a genetic disorder. In humans the gene is not sufficient by itself to cause narcolepsy. Something else triggers it, so that only one of a pair of identical twins might have it. We do not know what triggers it, but it could be an infection that triggers an auto-immune response. ...Read more

See 1 more doctor answer
Dr. Richard Roberts
228 doctors shared insights

Genetic Disease (Definition)

A genetic disease is a disease that is caused by a defect in the genetic (dna) material in a gene(s). It can be inherited and mosy pose a risk to other family members and/or to future children. For many genetic diseases there are molecular tests that allow detection of a change(s) called mutations, we can also detect deltions or other changes to the gene's dna that can also result ...Read more


2

2
Is it possible for bipolar disorders to be inherited?

Is it possible for bipolar disorders to be inherited?

Depression: Genetics play a role, so does the environment and your psyche (personality). ...Read more

See 2 more doctor answers
3

3
Autism spectrum disorder is a neurodevelopmental disorder. Is it possible that it could be genetic as well?

Autism spectrum disorder is a neurodevelopmental disorder. Is it possible that it could be genetic as well?

Yes: There is definite evidence that there is a genetic predisposition for most children that have autism. Though far from specifically identifiable based on genetic tests. More often enzyme based vulnerabilities. More milage in looking at how to moderate the environment to avoid triggering the vulnerabilities. ...Read more

See 1 more doctor answer
5

5
Is there a precursor condition to epilepsy?

Is there a precursor condition to epilepsy?

Yes: Epilepsy can be associated with problems during pregnancy and subsequently during labor and delivery. Some head traumas are complicated by epilepsy. A variety of brain lesions can cause epilepsy, and some medications can provoke seizures. Alcohol and recreational drugs (cocaine, speed) can result in seizures. ...Read more

6

6
Is there a hereditary component to tourette's syndrome?

Is there a hereditary component to tourette's syndrome?

Yes: The gene has not yet been identified, so mode of transmission is also unknown. Fathers usually have a history of tourette's or undiagnosed chronic tics, anxiety with features of OCD & adhd. Mothers may have a history of anxiety/ocd & adhd without tics because of partial penetrance of the gene. Because it can come from either parent, researchers look at autosomes, not the sex chromosomes. ...Read more

7

7
Is a genetic mutation considered a disorder only if it causes harm? Or are beneficial or harmless mutations considered disorders as well?

Is a genetic mutation considered a disorder only if it causes harm? Or are beneficial or harmless mutations considered disorders as well?

Depends: Interesting question, but fundamentally a semantic one. Harmless mutations are usually called variants rather than disorders. Also, external factors might make a mutation useful in one circumstance but not another. For example, the red cell mutation called G6PD deficiency can cause (mild) anemia, but in places where malaria is prevalent, it is somewhat protective for that disease. ...Read more

8

8
Could i be born with a genetic predisposition to bipolar disorder?

Could i be born with a genetic predisposition to bipolar disorder?

Yes: There's an incompletely understood genetic connection in bipolar disorder. The most convincing evidence is studies of monozygotic twins, in which there's increased likelihood of bipolar disorder in both twins if one presents with this disorder. Children of bipolar parents are at higher risk than others, of developing a mood disorder. Growing up with a bipolar parent brings risks also. ...Read more

9

9
Is it true that depression is considered a neurological disorder?

Is it true that depression is considered a neurological disorder?

Yes, but...: All psychological/psychiatric disorders/symptoms are neurological in the sense that they are all expressed through changes in the brain and nervous system. In that sense depression is a neurological disorder. However, the difference between depression and say parkinson's disease or stroke is that in many instances of depression, talk therapy is effective. ...Read more

See 1 more doctor answer
10

10
Can there be a problem with being narcissistic or why is it called personality disorder?

Can there be a problem with being narcissistic or why is it called personality disorder?

Yes, BIG problem: A personality disorder is an enduring, pervasive, and inflexible pattern of inner experience and behavior that differs markedly from one's culture, begins in adolescence or early adulthood, and causes distress in important areas of life (relationships, work, etc). Narcissistic pd causes problems b/c they are grandiose about themselves, need constant admiration, and can't empathize with others. ...Read more

See 1 more doctor answer
11

11
Is it possible to prove a diagnosis of mania or bipolar disorder?

Is it possible to prove a diagnosis of mania or bipolar disorder?

Prove To Who?: Mania is a cluster of symptoms that occur over seven days (or less if hospitalization or incarceration is required). You cannot prove that the mania was not drug induced but if a drug test and thyroid function is normal and there was no head trauma it is widely accepted to be a bipolar mania. ...Read more

12

12
Is narcolepsy a genetically inherited medical problem?

Is narcolepsy a genetically inherited medical problem?

Yes for Some People: Most patients with narcolepsy with cataplexy have a genetic marker called hla dqb1*0602. However, many people without narcolepsy also this same marker. As such, simply having the marker is not sufficient to cause the condition. The current thought is that in narcolepsy an infection triggers the immune system to attack cells in the brain which secrete a chemical (orexin) needed to keep you awake. ...Read more

See 1 more doctor answer
13

13
Is it possible that chronic depression leads to a personality disorder?

Is it possible that chronic depression leads to a personality disorder?

Doesn't cause PD: Personality changes can occur with depression but depression does not cause personality disorders. ...Read more

14

14
What is the genetic disorder progeria caused by? Is it a simple recessive trait?

Two likely forms: Progeria syndrome is considered a sporadic (new mutation) phenomenon that has few prenatal indicators. At an average birth wt of 6lb (2.7kg), the relatively small size during gestation is not specific to this disorder. There are rare instances of siblings to normal parents, showing that an autosomal recessive form exists.Most begin to show signs by 6-18mo. ...Read more

16

16
Why is ADHD considered as a disorder? Is it not more of a personality trait?

Why is ADHD considered as a disorder? Is it not more of a personality trait?

Disorder for sure!: Brain studies show differences between persons w/ & w/o adhd, particularly in the left prefrontal cortex. Nimh demonstrated that the brains of kids w/ adhd are 3-4% smaller than those w/o adhd. There is also evidence of differences in neurotransmitters such as norepinephrine & Dopamine (altho the differences are complicated). Adhd causes problems w/ learning, school performance & behavior. ...Read more

See 2 more doctor answers
18

18
Is it possible there is a mental health disorder linked to bullying?

Is it possible there is a mental health disorder linked to bullying?

Inferiority: Believe it or not, bullies tend to have inferiority complexes, often from having been bullied themselves. and yes, it can continue into adult life. Tell someone you know and trust about the bullying. Keeping it inside does no good. ...Read more

See 2 more doctor answers
19

19
What is a genetic disorder?

What is a genetic disorder?

Chromosomes abn.: A genetic disorder is an abnormality in the genetic makeup of an individual, abn expression of chromosomes, (your internal blueprint). This may have been inherited from parents, or a result of a spontaneous change in genes. Epogenetics is the expression of your genes and can be influenced by environment and nutrition. So it doesn't always have to "run in the family". ...Read more

See 1 more doctor answer
20

20
Is lying a symptom that can be explained by bipolar disorder?

It is a strategy: Lying is a strategy for many people. We lie to protect ourselves & to gain rewards. We lie when to tell a truth is difficult . People without any mental illness might lie at times for those reasons. With any mental disorder there can be more reasons to feel a need to lie. Bipolar disorder is often so difficult for the suffer to deal with that lying can happen a lot. Strategy, not symptom - right? ...Read more

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


Dr. Michelle Zetoony
287 doctors shared insights

Narcolepsy (Definition)

A condition characterized by extreme sleepiness every few hours during the day and frequent, unexpected sleep attacks. This sleep disorder is believed to be caused by a decrease in a protein in the brain. There is no cure for narcolepsy, but its ...Read more