Doctor insights on:
Is Multiple Sclerosis A Hereditary Condition
In part: Hereditary risk is one factor, but the interplay between genetic background and environment is likely in this disease. Identical twins studies show about a 30% risk for MS if one twin has the disease (certainly not 100%). Population studies show certain ancestry may increase or decrease risk (e.g. Northern european ancestry high, whereas asian, african, aboriginal very low). ...Read moreSee 2 more doctor answers
Several potentials: Cadasil, lupus, arteritis, clippers, pernicious anemia, cervical spondylosis, lyme disease, CNS lymphoma, sjogren's, melas. If you get the point, ms may be hard to diagnose, and often need to exclude other explanations. Patterns may or may not be different, and sometimes it is important to get testing and even several opinions. ...Read moreSee 1 more doctor answer
Several: The confirmation of ms involves excluding several diseases that seem similar at times. Perhaps the biggest challenge is cadasil, a genetic disorder associated with migraines and small strokes. However, other disorders can cause confusion such as lupus, lyme disease, b-12 deficiency, sjogren's, arteritis, and a number of rare disorders. The MRI may seem similar in some of these cases. ...Read more
Not primary cause: Ms is clearly influenced by genetics, as we are aware of risk profiles increasing genetic susceptibility and some genetic protective profiles; but, without a number of environmental influences, will not occur. So, like folks who get flu frequently, this is a vulnerability, but not a hereditary illness. ...Read more
Yes: No single gene for MS has been found or likely to be found. Multiple genes have been identified which in different population studies worldwide seem to increase risk or protect against ms. The vast majority of these genes relate to immune system function. Genetic background, combined with environmental trigger likely trigger this disorder. ...Read moreSee 2 more doctor answers
A friend of mine was recently diagnosed with primary progressive multiple sclerosis. Is this a fatal disease?
Cannot predict: Primary progressive ms is typically without rapid relapses, but also, without remission. Does not seem to respond well to meds employed in relapsing/remitting form. Most active therapy is symptomatic. However, research is ongoing with Gilenya (fingolimod) for ppms. Other drugs not yet on the market are being studied. Best bet is to get into one of these studies. Contact local medical school. Stay positive. ...Read more
- Talk to a doctor live online for free
- Multiple sclerosis
- Is pulmonary hypertension a hereditary condition?
- Is lichen sclerosis hereditary?
- Ask a doctor a question free online
- Is multiple myeloma contagious or hereditary?
- Multiple hereditary exostoses syndrome
- Multiple hereditary osteochondromatosis
- Hereditary multiple exostoses
- Talk to a clinical geneticist online for free