Doctor insights on:
Is Methrotrexate A Causative Factor For Pulmonary Fibrosis
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
I have pulmonary fibrosis stage 2, I am about to start methotrexate with the prednisone. Do you expect the fatigue to lessen after treatment?
Scarred Lungs: Pulmonary fibrosis is essentially scarring of the lungs. There are many different causes for the lungs to scar. The disease can be a long-term chronic problem however in certain cases if the underlying cause of scarring is not addressed, it can be fatal. Furthermore, idiopathic pulmonary fibrosis is almost uniformly fatal. Lung transplantation may be a final resort. ...Read more
No: Cirrhosis is associated with two other lung disorders which can cause similar symptoms to pulmonary fibrosis. These are called hepatopulmonary syndrome and portopulmonary hypertension. These only occur if cirrhosis is present. If it goes on long enough without treatment, portopulmonary hypertension can cause permanent injury to the lung. ...Read moreSee 1 more doctor answer
I have pulmonary fibrosis, cause as yet undetermined (never smoked). Please comment on the safety of putting nebulized DMSO into the lungs.
Not safe: I would advise you not to put any such chemical into your lungs. I do not know of any good medical/scientifically valid data that supports such a use for dmso. You could actually make matters worse by putting any foreign body/chemicals into your lung. So play it safe. ...Read moreSee 1 more doctor answer
SILICA,ASBESTOS,BIRD: Fibrosis in the lungs has many causes 1inhalation of silica dust, asbestos, grain dust, bird and animal droppings 2 radiation therapy for breast cancer 3medications like chemotherapeutic drugs and amiodarone, methotrexate, nitrofurantoin 4 secondary effect of other diseases likeinterstitial lung disease 5 idiopathic when no cause can be found 6 sarcoidosis and wegnors granulomata 7 connective tissue di. ...Read moreSee 1 more doctor answer
Yes: Pulmonary fibrosis causes the inner latticework of the lungs to thicken. Given that this latticework supports oxygen and carbon dioxide exchange, and that exchange is dependent on the thinness of the transport membrane, pulmonary fibrosis makes the lungs work less efficiently, leading to shortness of breath. ...Read moreSee 2 more doctor answers
Reflux: We have to individualise patients . There is no hard and fast rule for that. ...Read more
At the very end: At the end stages of pulmonary fibrosis, it can cause elevated blood pressure in the lungs, which can affect the heart. Also, the lack of oxygen from the fibrosis can also affect the heart. But, again, this occurs in the very end stages of the disease, usually. ...Read moreSee 1 more doctor answer
Some doctors say acid reflux can cause pulmonary fibrosis some says its not m worried had LPR since years?
After multiple respiratory, cardiac, and other organ tests, pulmonary fibrosis was ruled out as cause for my sob. Reduction of propranolol usage has helped somewhat, but not completely. What next?
Reduce completely?: So you've had a thorough investigation, all of which has been negative so far. Reducing your propanolol has helped but not completely. I'd venture to ask why not stop it completely then and replace w/another blood pressure medication. Surely there are others you can take that won't affect your breathing! if you need a rate limiting agent, consider Diltiazem or verapamil, which won't affect lungs. ...Read moreSee 3 more doctor answers
Aspirating a lot?: Exposure of the vocal cords to stomach acid ; pepsin will result in inflammation of the vocal cords (as is also often seen with acid regurgitation). Acute laryngitis may result, but watch out for chronic hoarseness, throat clearing, airway spasms, bronchitis, an asthma-type presentation, and even a higher risk of throat cancer. Impedance ph testing with a symptom diary can best characterize this. ...Read more
Few doc says acid reflux can cause pulmonary fibrosis few doc says not if silent reflux can cause pulmonary fibrosis wts time frame?
GERD: Well known extraesophageal( outside of feeding tube) manifestations include asthma, laryngitis, chronic cough, aspiration pneumonia, ch bronchitis, sleep apnea, dental caries, bad breath, and hiccups. Thus, it can damage lung tissues, at least in theory in a normal person. Surgical techniques can be used in the rare pts who are refractory to medical managements. ...Read more
Not usually: Acid reflux affects the esophagus and, at times, the upper respiratory passage(larynx, trachea) but i wouldn't expect pulmonary fibrosis or lung cancer as complications. If you have reflux, see your md for treatment and dietary advice in order to protect your esophagus from chronic changes. ...Read more
Inflammation: Tb is an infection which can cause an inflammatory reaction and scar tissue can be the result of that process. ...Read more
I hve breathlessness on very mild activity X-ray and pft are normal echo ECG normal, I am worrying for pulmonary fibrosis or COPD can LPR cause breat?
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