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Doctor insights on: Is Methrotrexate A Causative Factor For Pulmonary Fibrosis

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Is methrotrexate a causative factor for pulmonary fibrosis?

Is methrotrexate a causative factor for pulmonary fibrosis?

Yes: Rarely Methotrexate can cause fibrosis of the lungs. An inflammation (called pneumonitis) is more common. Lung function should be checked at least yearly while on this drug. ...Read more

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Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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What is COPD a risk factor for?

What is COPD a risk factor for?

See below: Having COPD can put you at risk for lung infections, cardiac issues, and pulmonary hypertension. ...Read more

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What is the treatment for idiopathic pulmonary fibrosis?

What is the treatment for idiopathic pulmonary fibrosis?

No good treatemtns: Unfortunately, there are no good, effective treatments for idiopathic pulmonary fibrosis. Many have been tried, such as steroids, anti-inflammatory drugs, and a drug called mucomyst, (acetylcysteine) but the studies done have not shown significant efficacy. Treatment is mainly supportive. ...Read more

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Since psoriasis is an autoimmune disease, would it be a risk factor for lymphoma?

Since psoriasis is an autoimmune disease, would it be a risk factor for lymphoma?

Yes, but: Probably not much of one. I cannot say I have seen much lymphoma it patients with bad psoriasis, and also don't note any increase in t cell disease which has a tendency to involve skin. ...Read more

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What is a common predisposing factor for pre-renal acute renal failure post-operatively?

What is a common predisposing factor for pre-renal acute renal failure post-operatively?

Surgery: Blood loss, inadequate volume resuscitation, excess diuretics, poor PO in take. Any thing that removes fluid from the body or reduces renal blood flow, such as low cardiac output. ...Read more

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Is there a definite cure for restrictive lung disease?

Is there a definite cure for restrictive lung disease?

Depends.: Too many types of restrictive lung disease to answer in this short space. I assume because you are asking the question that you have been told that you do not have a "cure". Many restrictive diseases are not curable, but there are good treatments. On the other hand morbid obesity may cause restriction and may be cured. ...Read more

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Is there a known genetic basis for lung cancer?

Is there a known genetic basis for lung cancer?

Genetic risk...: ...For lung cancer is a hot topic of research and there is a large national consortium studying families with multiple relatives having lung cancer to identigy genes that transmit risk. No one gene has been, or is likely to be, found, but multiple candidate "culprit" genes are under investigation. One barrier is finding families willing to participate. Look this up on cancer.Gov. ...Read more

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Dr. Al Hegab Dr. Hegab
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My father is diagnosed with idiopathic pulmonary fibrosis, copd, polycythemia and cronic asthmatic bronchitis. Is he a candidate for lung transplant?

Dr. Al Hegab Dr. Hegab
2 doctors agreed:
My father is diagnosed with idiopathic pulmonary fibrosis, copd, polycythemia and cronic asthmatic bronchitis. Is he a candidate for lung transplant?

Lung transplant: Other factors are considered too, as age, general health, other chronic diseases, the original lung disease and whether it can recur in the transplanted lung, your father needs to be evaluated in a tertiary care hospital, either a university or a teaching hospital, better if they have a transplant program, wish you wellness ...Read more

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Is Lpa a significant risk factor for heart disease or is LDL the most important. ?

Is Lpa a significant risk factor for heart disease or is LDL the most important. ?

Being worked out: Lp(a) is quite elevated is an independent risk factor that seems to be almost entirely hereditary, and may be managed with a different medication regimen. For the vast majority of us, LDL cholesterol is key, and it's always against the background of other risks. Avoid smoking, stay physically fit and trim, and hope for many years of good health. ...Read more

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Is there a hereditary component to Fothergills disease?

Is there a hereditary component to Fothergills disease?

Trigeminal neuralgia: There is no hereditary component for trigeminal neuralgia. No geographic tendency or racial differences have been found for trigeminal neuralgia. However, females are affected up to twice as often as males (range, 3:2 to 2:1). In addition, in 90% of patients, the disease begins after age 40 years, with a typical onset of 60-70 years (middle and later life). ...Read more

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What is the definition of pulmonary phibrosis? Is it linked to pulmonar hyper-tension? Is there a cure for & how does it compare to pulmonary edima?

What is the definition of pulmonary phibrosis? Is it linked to pulmonar hyper-tension? Is there a cure for & how does it compare to pulmonary  edima?

Lung scarring: Pulmonary fibrosis is scarring of the lung and comes in many types - some are amenable to treatment, some are not. It is often associated with pulm hypertension and not usually associated with pulm edema. Anyone with a diagnosis of pf should be seen by a pulmonologist so they can have their disease evaluated and poss treatments discussed. ...Read more

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What is emphysema vs copd? Is emphysema the same as chronic obstructive pulmonary disease?

Categories....: Copd, chronic obstructive pulmonary disease, is the broader category. Emphysema is one type of copd, ie emphysema falls under the category of copd. ...Read more

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How is it that oxygen supplementation is contraindicated for pts with obstructive lung diseas?

Hypoxic drive: In most patients with advanced chronic obstructive lung disease, chronic hypoxia (low oxygen levels) stimulates their drive to breathe at a faster rate to provide enough oxygen(o2) to the body. Giving supplemental o2 takes away this hypoxic drive that maintains their minute ventilation, thereby risking them going into respiratory failure, especially if their disease is advanced & they have bad pft. ...Read more

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What is the treatment for idiopathic pulmonary fibrosis ?

What is the treatment for  idiopathic pulmonary fibrosis  ?

None effective: Unfortunately there are no effective treatments for ipf. Currently n-acetyl cysteine and perfenidone are being studied, but at this time no effective treatment has been found. ...Read more

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Dr. Aaron Milstone
628 doctors shared insights

Pulmonary Fibrosis (Definition)

A lung condition in which there is progressive scarring of the lung tissue. Symptoms include shortness of breath, chest pain, fatigue, ...Read more


Dr. Walter Husar
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Respiratory (Definition)

Pertaining to the work of breathing done by the chest ...Read more