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Doctor insights on: Is Meconium Plug Syndrome Only Associated With Cystic Fibrosis

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Is meconium plug syndrome only associated with cystic fibrosis?

Is meconium plug syndrome only associated with cystic fibrosis?

No: Meconium plug syndrome, as opposed to meconium ileus, is not necessarily associated with cf. It can occur with hirschsprung's disease. It is usually self-limited, however, and clears with a contrast enema undertaken to establish the diagnosis. If the baby stools normally after initial evacuation, additional work-up is usually not necessary. ...Read more

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Dr. William Walsh
981 doctors shared insights

Cystic Fibrosis (Definition)

Cystic fibrosis is a genetic disorder of the lungs and digestive tract. It causes recurrent lung infections and inhibits growth in patients. Average life expectancy of patients with cystic fibrosis ...Read more


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My baby was born 4 weeks early and had a meconium plug that didn't pass till hour 57. Cystic fibrosis has been ruled out. What are the chances it's hirschsprungs? Or could it just be chance?

Likely it's chance: CF is one of the causes of meconium plug, but mostly it's a random happenstance. Ruling out CF is important. As long as your child is starting to have normal stools now, and they are fairly regular, it's very unlikely it's hirschsprungs. Generally anal stenosis, hirschsprungs, or other forms of obstruction would cause chronic constipation. If your child is stooling normally, i'd go with it. ...Read more

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How are meconium and meconium ileus in cystic fibrosis different?

Yes: Meconium is the normal fecal debris composing the accumulated intestinal contents at birth.It is heavily colored by bile, dark and sticky. Meconium ileus can occur when the meconium has abnormal glue like stickiness caused by CF and will not empty from the bowel.The blockage can require emergency surgery. ...Read more

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What is the difference between meconium aspiration and meconium ileus in cystic fibrosis?

What is the difference between meconium aspiration and meconium ileus in cystic fibrosis?

Meconium : Meconium is the poo you make in the womb but are not supposed to empty until after birth. It represents bile/swallowed hair & skin cells etc & is very sticky. If you poo before birth, usually due to stress, the stuff can circulate in the bag of waters. If that material gets into your lungs before, during or after labor it can cause lung disease. CF kids have poo that's too sticky & won't pass. ...Read more

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What are the chances my child will be born with chromosomal abnormalities? I was told my unborn child has echogenic bowels, that i tested higher for the risk of Down syndrome and as a carrier of the cystic fibrosis trait

What are the chances my child will be born with chromosomal abnormalities? I was told my unborn child has echogenic bowels, that i tested higher for the risk of Down syndrome and as a carrier of the cystic fibrosis trait

There : There are several ultrasound findings that can suggest down sysndrome, and echogenic bowel is one of them. There could be other explanations for that finding, though. It sound like you will need some testing to find out what's going on. The two tests used most commonly are amniocentesis and chorionic villous sampling. Each has its own risks and benefits, so you should discuss them with your obstetrician. I would suggest that you do this sooner than later, and regardless of whether the outcome might lead you to terminate the pregnancy. ...Read more

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What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

Overall 1/3700: Acording to the CF foundation: the overall birth prevalence is 1/3700 . It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000. More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read more

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How can cystic fibrosis affect p.I.E.S development?

How can cystic fibrosis affect p.I.E.S development?

Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US.A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications.Emotional & phys. development depend on severity, time in hospital, complications.Morb. & mort.factors afect emotional,cognitive behavior. ...Read more

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I have symptoms of cystic fibrosis. Is it possible to start show the symptoms in my 30's?

Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read more

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I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

Yes: However, usually an adult who is diagnosed so late has usually had chronic problems with cough and "pneumonias". That said i've diagnosed a new case in a 38 year old woman. ...Read more

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Does cystic fibrosis usually cause many symptoms?

Yes: The primary symptoms are pulmonary and digestive. Chronic lung disease and recurrent lung infections start early in life. Intestinal malapsortion because of digestive enzyme deficiency also occurs early. Other symptoms include meconium illius in the perinatal period, growth failure in childhood and a variety of symptoms in the second and third decades of life including diabetes. ...Read more

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