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Doctor insights on: Is Lupus Anticoagulant Hereditary

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Dr. Clarence Grim Dr. Grim
Internal Medicine - Endocrinology
53 years in practice
University of Missouri-Columbia School of Medicine
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I was told my lupus anticoagulant was inherited. Can it be?

I was told my lupus anticoagulant was inherited. Can it be?

Lupus anticoagulant: Yes, Discuss with your Dr and go to upgtodate. Com for review.

Dr. Boris Aronzon
527 Doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


Dr. Katherine Sutherland Dr. Sutherland
Gynecology
39 years in practice
Stanford University School of Medicine
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What is the lupus anticoagulant?

What is the lupus anticoagulant?

Clotting antibody: The lupus anticoagulant is a phospholipid antibody that can bind to cell membranes to make them sticky and increase the risk of blood clotting. It can occur transiently as the result of infections or medicines, or it can occur as spontaneous auto-antibodies or with autoimmune diseases. It may increase the risk of infertility or recurrent miscarriages.

Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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How does someone get lupus anticoagulant?

How does someone get lupus anticoagulant?

Part of lupus: You produce antibodies that can interact with the process of blood clotting to cause the blood to clot more easily than normal. This is part of the immunologic abnormalities associated with lupus in some affected individuals.

Dr. Bruce Rothschild Dr. Rothschild
Internal Medicine - Rheumatology
37 years in practice
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School
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How many lupus anticoagulant tests are there?

How many lupus anticoagulant tests are there?

Many: There are tests for 3 forms of anticardiolipin antibodies, 3 forms of antiphospholipid antibodies, russell viper coagulation test and tests for specific components of coagulation and general tests (e.g., prothrombin time).

Dr. Arthur Torre Dr. Torre
Pediatrics - Allergy & Asthma
47 years in practice
University of Medicine and Dentistry of New Jersey - New Jersey Medical School
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Do people with lupus have the lupus anticoagulant?

Do people with lupus have the lupus anticoagulant?

Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease.

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Dr. Nikolaos Zacharias Dr. Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine
22 years in practice
National University of Athens Faculty of Medicine
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What medicine do I take for the lupus anticoagulant?

None.: Lac is a laboratory finding of uncertain clinical significance. It predisposes to the development of autoimmune diseases such as lupus erythematosus, vitiligo, pernicious anemia, thyroiditis, inflammatory bowel disease, type I diabetes mellitus and addison's disease. If your rheumatologist has diagnosed you with a particular disorder, medications may be warranted on a clinical basis - not for lac.

Dr. Budi Bahureksa Dr. Bahureksa
Internal Medicine - Cardiology
27 years in practice
Kansas City University of Medicine and Biosciences College of Osteopathic Medicine
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Dr. Arthur Mandelin Dr. Mandelin
Internal Medicine - Rheumatology
16 years in practice
George Washington University Medical School
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What is the definition or description of: lupus anticoagulant?

Poorly Named Test: If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune disease should have done.

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Dr. Bruce Rothschild Dr. Rothschild
Internal Medicine - Rheumatology
37 years in practice
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School
9
Dr. Nikolaos Zacharias Dr. Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine
22 years in practice
National University of Athens Faculty of Medicine
10
Dr. Tracy Lovell Dr. Lovell
Internal Medicine - Rheumatology
17 years in practice
Medical College of Georgia School of Medicine
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Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it.

Dr. Douglas Mund Dr. Mund
Internal Medicine - Rheumatology
42 years in practice
State University of New York Downstate Medical Center College of Medicine
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I was recently tested for lupus anticoagulant and it was postitive. Does that mean I have lupus?

No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for.

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Dr. Atif Haque Dr. Haque
Neurosurgery
14 years in practice
University of Mississippi School of Medicine
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I have lupus anticoagulant and dr. Is wanting to put me on xorelto! I've read mixed reviews mostly against, & cost is a factor? What is your opinion?

I have lupus anticoagulant and dr. Is wanting to put me on xorelto! I've read mixed reviews mostly against, & cost is a factor? What is your opinion?

Use caution: Xarelto is awesome if you listen to the manufacturer. Unlike coumadin, (warfarin) you do not require regular blood draws to evaluate effect. However, there is also no clear reversal agent if one does sustain a bleed. It can be a terrible situation when someone has a brain hemorrhage, etc, from relatively trivial fall.

Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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What tumors can cause lupus anticoagulant?

Several: Several tumors can cause the anticoagulant with lung cancer one of the most common.

Dr. George Mathew Dr. Mathew
Internal Medicine - Cardiology
54 years in practice
Mangalore University, Kasturba Medical College
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Need information on circulatory lupus anticoagulant?

Need information on circulatory lupus anticoagulant?

See below: It is an immunoglobulin that binds to protein and phospholipids of the cell membrane. In fact it can be prothrombotic unless treated with an anticoagulant such as coumadin!

Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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Can I get disability for lupus anticoagulant disorder.

Can I get disability for lupus anticoagulant disorder.

Impossible to say: It depends on many factors, not just on a diagnosis. If you are able to work, you are not disabled no matter what the underlying medical issues.

Dr. Andrew Blazar Dr. Blazar
Obstetrics & Gynecology
58 years in practice
Tufts University School of Medicine
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What are dangers of conceiving if one has lupus anticoagulant and pcos?

Danger small but. ..: Pcos makes becoming pregnant difficult without treatment; pregnancy is usually ok though excess weight raises risk mildly; lupus anticoagulant requires careful study and may raise the risk of late miscarriage and require special treatment throughout pregnancy.

Dr. Bruce Rothschild Dr. Rothschild
Internal Medicine - Rheumatology
37 years in practice
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School
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Dr. Nikolaos Zacharias Dr. Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine
22 years in practice
National University of Athens Faculty of Medicine
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How risky is it to get pregnant with lupus anticoagulant?

No big deal usually.: Depending on whether you have a diagnosis of lupus or prior clotting problems, this may or may not be significant for your pregnancy. Studies show that most women with lac have normal pregnancies. Lupus anticoagulant (lac) is a laboratory finding and in and of itself not significant for predicting clinical outcomes. If you have systemic lupus erythematosus the plot thickens and you need to see mfm.

Dr. Nikolaos Zacharias Dr. Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine
22 years in practice
National University of Athens Faculty of Medicine
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Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes.

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Lupus Anticoagulant (Definition)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more