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Doctor insights on: Is It Sle Or Lupus Anticoagulant That Causes Pregnancy Problems

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Is it sle or lupus anticoagulant that causes pregnancy problems?

Is it sle or lupus anticoagulant that causes pregnancy problems?

Lupus and pregnanacy: Sle or lupus is less likely to cause serious problems in pregnanacy if the disease is well controlled before conception, especially if you are cared for by both a rheumatologist and "high risk" ob. Also presence of lupus anticoagulant can be managed suceesfully. ...Read more

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Dr. Boris Aronzon
503 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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I tested weakly positive for lupus anticoagulant. I have been on baby aspirin for 2months now, can I have a successful pregnancy on that alone?

I tested weakly positive for lupus anticoagulant. I have been on baby aspirin for 2months now, can I have a successful pregnancy on that alone?

See details: A low positive test is not clinically significant so no preventative therapy is needed. There is no evidence that low dose ASA has any value in this situation. ...Read more

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I have been having recurrent miscarriages.I tested weakly positive for lupus anticoagulant. Can I have a successful pregnancy on baby aspirin?

No: Low dose Aspirin is not an effective therapy for this issue. You need to be on subcutaneous heparin. See a rheumatologist or hematologist for appropriate treatment. ...Read more

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Thrombin 14.5,PT 22.7,APTT 79 all prolonged. APTT mix not corrected, CH50-low @22, C4 norm, C3 low. SLE pt. Lab says other results prove it is not lupus anticoagulant. What else could cause this? C3 almost always low,C4 never low. Creatnine 1.4.

Anti-phospholipid Ab: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, there is a specific for "lupus anticoagulant", i.e., antibody to phospholipid. See this site for more info. http://www.nhlbi.nih.gov/health/health-topics/topics/aps/diagnosis ...Read more

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Earlier this year I had prolonged PT and aptt, w/prolonged thrombin time. Mixing study did not correct. Dr thought lupus anticoagulant.Coagulation studies this mo show only prolonged Thrombin time. Have SLE. Do coagulation studies change like that?

Earlier this year I had prolonged PT and aptt, w/prolonged thrombin time. Mixing study did not correct. Dr thought lupus anticoagulant.Coagulation studies this mo show only  prolonged Thrombin time. Have SLE. Do coagulation studies change like that?

What else changed: we also like to have two repeat positive tests to make a diagnosis. Were you on any diferent medications that might have had an effect on the tests. These results should be discussed with your rheumatologist. ...Read more

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Do people with lupus have the lupus anticoagulant?

Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read more

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What medicine do I take for the lupus anticoagulant?

None.: Lac is a laboratory finding of uncertain clinical significance. It predisposes to the development of autoimmune diseases such as lupus erythematosus, vitiligo, pernicious anemia, thyroiditis, inflammatory bowel disease, type i diabetes mellitus and addison's disease. If your rheumatologist has diagnosed you with a particular disorder, medications may be warranted on a clinical basis - not for lac. ...Read more

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I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

Depends on history: This test should always be confirmed by repeat and other related tests a prior history of multiple late pregnancy losses and /or unexplained clots make the test more ominous. ...Read more

Dr. Hirenkumar Italia
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Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more