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Doctor insights on: Is It Possible To Not Be Allergic To Medicine If You Developed Hives

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Are hives ever just a side effect of a drug, or are they always considered an allergic reaction?

Are hives ever just a side effect of a drug, or are they always considered an allergic reaction?

Not always: Hives may be caused by many things including viral infections. Some drugs like opiates trigger certain types of cells to release histamine and thereby causing hives. Only on rare occasions are hives caused by airborne allergens. On the other hand, drug allergy can indeed cause hives. ...Read more

Dr. Neigatha Graney
3 Doctors shared insights

Hives (Definition)

An outbreak of red bumps or wheals that appear quickly after exposure to certain allergens (foods, medications, other substances). They can vary in size, are itchy, can burn, and can last for up to ...Read more


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Does a person who has multiple drug allergies and is also just prone to hives also have to avoid high-risk foods even if not officially allergic?

Does a person who has multiple drug allergies and is also just prone to hives also have to avoid high-risk foods even if not officially allergic?

Not usually: The cause for multiple drug allergies to unrelated drugs remains to be established but there is no relationship to food allergies. ...Read more

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I have been taking Flonase for two days and have since broken out in hives. I am allergic to ceclor. What shld I do? Other medicines I shld worry abt 

I have been taking Flonase for two days and have since broken out in hives. I am allergic to ceclor. What shld I do? Other medicines I shld worry abt 

Hives: The Flonase is probably for allergic rhinitis. Have u ever had hives before? If not, then stop the Flonase and see if the hives go away. Then restart the Flonase after the hives are completely gone for 1 week. If the hives recur, then u know it is the flonase. If the hives stay or u have had them before, it is probably something else. You could also try some otc oral antihistamines for the hives. ...Read more

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What syms would I have if allergic to nsaids? I'm a chronic hive sufferer, & get hives w nsaids, but no other sym's. My usual hives, or drug reaction?

What syms would I have if allergic to nsaids? I'm a chronic hive sufferer, & get hives w nsaids, but no other sym's. My usual hives, or drug reaction?

A drug reaction: If you have chronic recurrent hives (also called chronic urticaria), that is one entity, which often has no obvious cause and can be very difficult to treat (allergist, dermatologist or immunologist area). But if you get hives after taking a non-steroidal antiinflammatory drug, then you are allergic to nsaids-stop taking them; you may get a severe, life-threatening reaction one time. ...Read more

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My allergic drug reactions usually consist of hives. Now that I take xyzal&zantac, am I at least somewhat protected from drug reactions if one occurs?

My allergic drug reactions usually consist of hives. Now that I take xyzal&zantac, am I at least somewhat protected from drug reactions if one occurs?

Yes: Both of those medicines help treat allergic reactions, but if you are very sensitive you still may get hives. If you have breathing difficulties from a reaction seek emergency care immediately. ...Read more

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When injected w morphine, instant hives, flushing. When I take vicodin, little rashes, itching. Am I allergic, or do these types drugs just do this?

When injected w morphine, instant hives, flushing. When I take vicodin, little rashes, itching. Am I allergic, or do these types drugs just do this?

Avoidance: Of those drugs or other drugs containing codeine, which a derivative of morphine, often times it is a side effect, not a true allergic reaction, but you cannot tell which of which, if you really need those drugs and have no other alternative consult an allergist/immunologist either yourself or through your treating physician, vheck aaaai. Org or acaai. Org for an allergist in your area, goodluck ...Read more

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My mother is allergic to antibiotics including sulfa drugs. She got hives really bad from e-mycin. Alternative antibiotics?

My mother is allergic to antibiotics including sulfa drugs. She got hives really bad from e-mycin. Alternative antibiotics?

Talk to Doctor: There are a wide range of other antibiotics including penicillins, but the choice of antibiotic would depend on the condition/bacteria being treated. Your doctor should be able to find a suitable alternative that are not in these classes of drugs. Allergists specialize in drug reactions and can get to the bottom of what drugs your mother can tolerate and what drugs your mother should avoid. ...Read more

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What do you suggest if my mother is also allergic to antibiotics including sulfa drugs. She got hives really bad from e-mycin. I?

What do you suggest if my mother is also allergic to antibiotics including sulfa drugs. She got hives really bad from e-mycin. I?

Question Not Clear: If your question is are you allergic to sulfa because your mother is, unless you have had a reaction to sulfa, the answer is no. You do not inherit specific allergies from your parents, only the non-specific global tendency to develop allergies. ...Read more

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I'm worried because my mother is also allergic to antibiotics including sulfa drugs. She got hives really bad from e-mycin. I, what do you suggest?

I'm worried because my mother is also allergic to antibiotics including sulfa drugs. She got hives really bad from e-mycin. I, what do you suggest?

See Allergist: Allergists specialize in drug reactions and can get to the bottom of what drugs your mother can tolerate and what drugs your mother should avoid. Make an appointment so that they can get a more detailed clinical history and perform testing or perform an in-office challenge if indicated. ...Read more

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I've had a few hives after taking many unrelated drugs, such as tylenol, (acetaminophen) nsaids, keflex, mestinon, & others. How can I be allergic to every med?

I've had a few hives after taking many unrelated drugs, such as tylenol, (acetaminophen) nsaids, keflex, mestinon, & others. How can I be allergic to every med?

Uncommon: This is a condition known as multiple drug sensitivity syndrome and the mechanism is unknown. I suspect however that at least some of these reactions are coincidental and you need to consult an allergist to get this issue sorted out. Challenge test may be in order. ...Read more

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I get hives everytime I take cold medicine. I can take ibuprofen though. So I think I may be allergic to acetaminophen. But I took benadryl & got hives?

I get hives everytime I take cold medicine. I can take ibuprofen though. So I think I may be allergic to acetaminophen. But I took benadryl & got hives?

Check ingredients: It is unusual to develop hives from Benadryl and thus I would suggest that you copy down all of the ingredients in each of the cold medicines you suspected might have caused hives to find out if there is a shared ingredient then go on doing your detective work from there. ...Read more

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I HAVE HYPERTHYROID (GRAVES) I AM ALLERGIC TO ANTI- THYROID DRUG. I broke out in hives last year MY CURRENT LAB RESULTS ARE SCARING ME. -JOHVANA?

I'm scared too: Please forgive my frankness. If hyperthyroidism isn't managed, you can go into thyroid storm and it's a coin toss whether you die. You got hives from your meds? You may need to take them anyway -- OR you may need to accept therapy with radioactive iodine. If you're resisted this in the past, it's time to reconsider. If it's not been offered, ask why. ...Read more

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What are common treatments for cholinergic urticaria? List medicine, dosage, etc 5 mg Levocetrizine no effect history: allergic rhinitis

What are common treatments for cholinergic urticaria? List medicine, dosage, etc 5 mg Levocetrizine no effect history: allergic rhinitis

Anthistamines: Antihistamines are main treatment for cholinergic urticaria, but sometimes must take more than normal dose. You can try twice daily dosing of cetrizine (10 mg twice a day) or twice daily dosing of fexofenadine (180 mg twice a day). If this regimen not working, I suggest seeing an allergist to further manage/evaluate. ...Read more

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Can drugs cause hives?

Yes: Any drug can cause hives. Some drugs may take minutes, others a few hours. ...Read more

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What is the mediine for hives?

What is the mediine for hives?

Antihistamines: Hives can be treated with otc antihistamines like benadryl, (diphenhydramine) zyrtec. They tend to resolve once the trigger has abated. Anything prolonged >3 days must be examined by a medical professional. ...Read more

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How can you tell whether you have hives or allergic reactions?

Histamine driven: Hives (or welts) are histamine driven reactions. These lesions come and go within hours and do not leave scales or marks. Hives can be a form of allergic reaction (ie to drugs or shellfish), but they can often be idiopathic (unknown trigger). Because we know this is a histamine driven problem, we treat with oral antihistamines, or oral steroids if severe and associate with wheezing. ...Read more

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Every time I go into the cold I get hives. Could I be allergic?

Every time I go into the cold I get hives. Could I be allergic?

Cold urticaria: Hives occurring while exposed to cold or while warming up after cold exposure are in a class of non-allergic conditions called physical urticaria. No allergy antibodies are involved. Antihistamines taken 30-60 minutes before exposure may help. Swimming in cold ocean water can be fatal for those with cold urticaria. ...Read more

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What are the types of allergic reactions? Do they always result in hives?

What are the types of allergic reactions? Do they always result in hives?

No: There are many types of allergy and not all result in hives. The more talked-about type involves IgE-antibody and these reactions commonly involve hives (but be careful, hives do not equal allergy). IgE is a form of "memory" for the immune system. Another form is T-cell (a white blood cell) that is involved in "delayed" allergy (eg poison ivy, some sulfa reactions) usually with diffuse rash... ...Read more

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Can hives from reacting to medicine show up days after taking it or do they have to show up within hours?

Can hives from reacting to medicine show up days after taking it or do they have to show up within hours?

Sometimes: The allergic reaction involving skin is DELAYED however if previously "sensitized" (exposed to the allergen with a delayed response in the past) the reaction can not only be immediate it can involve the airways and result in a dangerous reaction (anaphylaxis)!
Hope this is helpful
Dr Z ...Read more

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Can each of my meds be tested on me somehow to find out which, if any, are causing my hives/ allergic reactions?

Hives: No. Hives can be due to many things including meds, foods, infections, autoimmune, irritation, underlying disorders, etc... It is also not possible to simply believe it is one of your medications. People always want a "cause and effect" but rarely is there one. An allergist can help. ...Read more

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I have hives but im not allergic to anything. How did I get it?

I have hives but im not allergic to anything. How did I get it?

Hive triggers: Hives can be a manifestation of allergies, viral infections (especially in children), bacterial infections such as strep, physical triggers like cold and heat. If hives persist beyond 6 weeks, then autoimmune trigger is possible and there continues be a large group of patients with "idiopathic" hives (cause unknown). ...Read more

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How can I preventmy hives from an allegic reaction from itching?

How can I preventmy hives from an allegic reaction from itching?

Antihistamines: Trials of antihistamines, usually starting with the non-sedating and low-sedating ones such as Allegra (fexofenadine) and zyrtec. There is a whole list of drugs that we work through. ...Read more

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What over-the-counter drug should I take for hives?

Hives treatment: If your diagnosis is correct, you can try any otc allergy meds like claritin, (loratadine) allergra, zyrtec or their equivalent generic forms. If it does not improve or you have hives more than 6 weeks, you should see either a dermatologist or an allergist. Remember hive lesions do not stay at the same place for more than 1 day. If they do, see a doctor to have an accurate diagnosis and treatment. ...Read more

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Why do I get hives even if I'm are not allergic to any foods?

Why do I get hives even if I'm are not allergic to any foods?

Chronic Urticaria: Chronic idiopathic or spontaneous urticaria (hives) is the persistence of hives on most days of the week for a period of 6 weeks or longer. It is not due to any medication or food trigger. No specific cause can be identified in most patients with this condition. Treatment involves daily doses of non-sedating antihistamines like Zyrtec (cetirizine). See Allergist for more details and treatment options. ...Read more