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Doctor insights on: Is It Possible For A Doctor To Diagnose Cirrhosis Without A Biopsy

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Is it possible for a doctor to diagnose cirrhosis without a biopsy?

Is it possible for a doctor to diagnose cirrhosis without a biopsy?

Yes, clincal dx: Although cirrhosis is classically a biopsy diagnosis, it is not always needed if there is sufficient clinical, lab, and radiologic data to suggest the presence of cirrhosis. For example, accumulation of fluid in the abdomen (ascites), bleeding disorders, jaundice, lab abnormalities, confusion and certain appearance of the liver on imaging may suggest cirrhosis without the need for biopsy. ...Read more

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Dr. Cornelius O'leary jr
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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Is it possible to diagnose liver cirrhosis or liver cancer without a biopsy?

Is it possible to diagnose liver cirrhosis or liver cancer without a biopsy?

Yes and no: Cirrhosis is a histologic diagnosis but can made without a biopsy with almost certainty based on lab data, imaging studies and physical exam. Liver cancer (hcc) is also a histologic diagnosis, but in the setting of cirrhosis it can be made based on MRI or ct imaging criteria without a biopsy with >95% certainty. ...Read more

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I did a search for diagnosis of some of my symptoms and came up with cirrhosis of the liver. What do doctors look for to diagnose it?

I did a search for diagnosis of some of my symptoms and came up with cirrhosis of the liver. What do doctors look for to diagnose it?

Ultrasound, liver bx: Cirrhosis can sometimes be diagnosed by non-invasive tests like ultrasound or ct scan. Sometimes a liver biopsy is necessary to make the diagnosis of cirrhosis. Other times blood work can show liver functions consistent with cirrhosis. ...Read more

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Give me a hint. What kind of hassle am I facing if doc suspects biliary cirrhosis? What is required to diagnose?

Give me a hint. What kind of hassle am I facing if doc suspects biliary cirrhosis? What is required to diagnose?

Serologies, liver bi: If you are referring to primary biliary cirrhosis, this is a type of autoimmune disease of unknown cause. Most commonly found in females. In the past, it used to be diagnosed very late in its course and usually when there was liver failure. Nowadays, and with the frequent use of blood test is diagnosed very early. Actigall/urso is the mainstay of treatment. Hematologist or gastro should monitor yo. ...Read more

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How many biopsys are needed to rule out alcohol cirrhosis?

One: Only one biopsy is sufficient to make a diagnosis of alcoholic cirrhosis. A biopsy with sufficient tissue is also suitable of ruling our cirrhosis. ...Read more

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Does a normal liver biopsy rule out cirrhosis?

Does a normal liver biopsy rule out cirrhosis?

Cirrhosis: Yes, the purpose of a liver biopsy is to look for any inflammation or fibrosis (cirrhosis) of the liver. A normal liver biopsy mean you don't have cirrhosis. ...Read more

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Are there any alternatives to a liver biopsy for cirrhosis, the procedure terrifies me?

Are there any alternatives to a liver biopsy for cirrhosis, the procedure terrifies me?

Liver biopsy: A liver biopsy is essential for establishing a diagnosis. Best of luck. Speak with the physician doing the biopsy and ask for something to relax you. ...Read more

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Had biopsy, the report says "consistent with AIH with impending Cirrhosis(inflammation grade 2 out of 4, fibrosis stage 5 out of 6)" what is this?

Had biopsy, the report says "consistent with AIH  with impending Cirrhosis(inflammation grade 2 out of 4, fibrosis stage 5 out of 6)" what is this?

Liver biopsy: The report indicates you have cirrhosis, a disease of your liver which can have many different causes. Cirrhosis is most commonly caused by alcohol, hepatitis B, hepatitis C, and non-alcoholic fatty liver disease. Speak with your doctor for more information and treatment options. ...Read more

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I had a liver biopsy done, stage 4 cirrhosis, could you please tell me how bad this is??

I had a liver biopsy done, stage 4  cirrhosis, could you please tell me how bad this is??

Very serious: This is so serious that you would do well to have ie read by.a second pathologist. You also need to determine the cause of the cirrhosis. Usually it is partly reversible if you find and can treat the cause. ...Read more

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What types of cirrhosis can a liver biopsy and fibroscan miss?

What types of cirrhosis can a liver biopsy and fibroscan miss?

You are okay man!: A Biosy that is adequate and that does not show cirrhosis rules out cirrhosis and our question is how to help a thoughtful guy like yourself to be comfortable. A second pathologist reading is available if you wish, or a consult with a specialist in emotions. ...Read more

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Does a normal Fibrotest, Fibroscan and liver biopsy 100% rule out cirrhosis?

Does a normal Fibrotest, Fibroscan and liver biopsy 100% rule out cirrhosis?

Cirrhosis: Nothing is 100% in medicine but all 3 of these tests are normal making it improbable that you have cirrhosis. ...Read more

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Is there anything that can mimic cirrhosis symptoms? fibroscan and biopsy was negative for liver scarring

Is there anything that can mimic cirrhosis symptoms? fibroscan and biopsy was negative for liver scarring

Liver cirrhosis: Cirrhosis of the liver has a large number of symptoms, many of which occur in other ailments. Severe swelling occurs also in heart failure & certain kidney diseases, itching occurs with allergy, jaundice can occur with hemolysis (breaking of red blood cells within blood stream), confusion has a large number of causes. Many other symptoms also exist for cirrhosis. ...Read more

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I am convinced i have cirrhosis despite normal liver biopsy and fibroscan. i can't stop thinking about it. could this be psychological?

I am convinced i have cirrhosis despite normal liver biopsy and fibroscan. i can't stop thinking about it. could this be psychological?

You're a wise man!: It's quite common for a person to have an idea that they have a particular, serious illness and not be able to get that idea out of their head -- even if they rationally know that it's wrong. Truth be told, you're far more clever than most such folks simply to recognize that this is happening to you. These thoughts can be treated like any other illness, with a good outcome expected. Ask your Dr. ...Read more

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Biopsy shows liver fibrois bridging cirrhosis. how long until progress to cirrhosis if drinking one shot of vodka every other day.months or years?

What are you asking?: Please forgive my frankness. And listen to yourself. Are you trying to kill yourself? Or are you playing chicken with your liver? Surely you are not unable to live without vodka? If it fills some emotional need, there are other med that can give you a similar good feeling that won't make your awful disease speed up? With total sobriety your liver may heal. Dying from cirrhosis is horrible. ...Read more

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How many liver biopsies are needed to rule out cirrhosis caused by alcohol? does it damage the liver evenly or in patches? is a fibroscan a good alt?

Bx and cirrhosis: Repeated liver biopsies are not necessary. Liver may be affected in heterogeneous fashion. Fibroscan is a good noninvasive test if available in your area. Blood tests can be helpful. Platelet count less than 150,000 is suggestibility cirrhosis. Fibrosure blood test or ultrasound can be helpful as well. ...Read more

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Had a biopsy which determined cirrhosis does this procedure itself injure a liver further; my protein and bilirubin went high for the very 1st time?

Had a biopsy which determined cirrhosis does this  procedure itself  injure a liver further; my  protein and bilirubin went high for the very 1st time?

Unlikely: Hepatic biopsy is unlikely to significantly damage the liver further. In cirrhosis the Albumin diminishes while the bilirubin may increase. You need to discuss this with the doctor performing the procedure and providing care. Good luck. ...Read more

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How accurate is a Fibroscan in detecting advanced fibrosis/cirrhosis of the liver? Biopsy is out of the question

How accurate is a Fibroscan in detecting advanced fibrosis/cirrhosis of the liver? Biopsy is out of the question

Fibroscan: Liver biospy is the gold standard to diagnose liver issues. Fibroscan is a good alternative to screen for any liver fibrosis which may indicate liver disease. ...Read more

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QUESTION FOR HEPATOLOGISTS: Could two Fibroscans and 3 ultrasounds miss advanced liver cirrhosis? Biopsy is out of the question

Reasonable test: If biopsy if unreasonable, the a fibroscan is a reasonable alternative. It is quite specific, meaning that if you are low value/result that it's unlikely that you have advanced fibrosis/cirrhosis, the actual percentage or specificity value, depends on your cut off point. So if you provide your specific results docs here may be better able to guide you. ...Read more