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Doctor insights on: Is It Possible For A Doctor To Diagnose Cirrhosis Without A Biopsy

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Is it possible for a doctor to diagnose cirrhosis without a biopsy?

Is it possible for a doctor to diagnose cirrhosis without a biopsy?

Yes: The "gold standard" of diagnosis is biopsy, but the history, physical examination, and lab tests, including liver scans and ultrasound, can strongly suggest the diagnosis to the point where a biopsy may not be necessary. New kinds of ultrasound and MRI imaging can actually determine the amount of scarring present. Most doctors will still want a biopsy to determine the severity of cirrhosis. ...Read more

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Dr. Andrew Seibert
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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Is it possible to diagnose liver cirrhosis or liver cancer without a biopsy?

Is it possible to diagnose liver cirrhosis or liver cancer without a biopsy?

Yes and no: Cirrhosis is a histologic diagnosis but can made without a biopsy with almost certainty based on lab data, imaging studies and physical exam. Liver cancer (hcc) is also a histologic diagnosis, but in the setting of cirrhosis it can be made based on MRI or ct imaging criteria without a biopsy with >95% certainty. ...Read more

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Give me a hint. What kind of hassle am I facing if doc suspects biliary cirrhosis? What is required to diagnose?

Give me a hint. What kind of hassle am I facing if doc suspects biliary cirrhosis? What is required to diagnose?

Serologies, liver bi: If you are referring to primary biliary cirrhosis, this is a type of autoimmune disease of unknown cause. Most commonly found in females. In the past, it used to be diagnosed very late in its course and usually when there was liver failure. Nowadays, and with the frequent use of blood test is diagnosed very early. Actigall/urso is the mainstay of treatment. Hematologist or gastro should monitor yo. ...Read more

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I did a search for diagnosis of some of my symptoms and came up with cirrhosis of the liver. What do doctors look for to diagnose it?

I did a search for diagnosis of some of my symptoms and came up with cirrhosis of the liver. What do doctors look for to diagnose it?

Ultrasound, liver bx: Cirrhosis can sometimes be diagnosed by non-invasive tests like ultrasound or ct scan. Sometimes a liver biopsy is necessary to make the diagnosis of cirrhosis. Other times blood work can show liver functions consistent with cirrhosis. ...Read more

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How many biopsys are needed to rule out alcohol cirrhosis?

One: Only one biopsy is sufficient to make a diagnosis of alcoholic cirrhosis. A biopsy with sufficient tissue is also suitable of ruling our cirrhosis. ...Read more

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Are there any alternatives to a liver biopsy for cirrhosis, the procedure terrifies me?

Are there any alternatives to a liver biopsy for cirrhosis, the procedure terrifies me?

Liver biopsy: A liver biopsy is essential for establishing a diagnosis. Best of luck. Speak with the physician doing the biopsy and ask for something to relax you. ...Read more

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I had a liver biopsy done, stage 4 cirrhosis, could you please tell me how bad this is??

I had a liver biopsy done, stage 4  cirrhosis, could you please tell me how bad this is??

Very serious: This is so serious that you would do well to have ie read by.a second pathologist. You also need to determine the cause of the cirrhosis. Usually it is partly reversible if you find and can treat the cause. ...Read more

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Had biopsy, the report says "consistent with AIH with impending Cirrhosis(inflammation grade 2 out of 4, fibrosis stage 5 out of 6)" what is this?

Had biopsy, the report says "consistent with AIH  with impending Cirrhosis(inflammation grade 2 out of 4, fibrosis stage 5 out of 6)" what is this?

Liver biopsy: The report indicates you have cirrhosis, a disease of your liver which can have many different causes. Cirrhosis is most commonly caused by alcohol, hepatitis B, hepatitis C, and non-alcoholic fatty liver disease. Speak with your doctor for more information and treatment options. ...Read more

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Does a normal liver biopsy rule out cirrhosis?

Does a normal liver biopsy rule out cirrhosis?

Cirrhosis: Yes, the purpose of a liver biopsy is to look for any inflammation or fibrosis (cirrhosis) of the liver. A normal liver biopsy mean you don't have cirrhosis. ...Read more

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What types of cirrhosis can a liver biopsy and fibroscan miss?

You are okay man!: A Biosy that is adequate and that does not show cirrhosis rules out cirrhosis and our question is how to help a thoughtful guy like yourself to be comfortable. A second pathologist reading is available if you wish, or a consult with a specialist in emotions. ...Read more