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Doctor insights on: Is It Okay To Take Amitriptyline With A Low Dose Of Tramadol For Pain

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Is it okay to take amitriptyline with a low dose of tramadol for pain?

Is it okay to take amitriptyline with a low dose of tramadol for pain?

Physician can decide: Tramadol and Amitriptyline both exert some effect on serotonin containing nerve pathways. There is potential interaction between the two. Treating physician can make a decision to combine the two in a regimen when benefits outweigh any potential risk. ...Read more

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Dr. Robert Kent
363 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


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Is it safe to take amitriptyline with a low dose of tramadol for pain?

Is it safe to take amitriptyline with a low dose of tramadol for pain?

Take Genetic Test: You might be able to take both low dose Amitriptyline and low dose tramadol for pain, depending on your genetics. You can have (cheek swab) pharmacogenomic tests done at the doctor's office (e.g. Assurex, genomind) to determine how you metabolize psychiatric and pain meds. In this way, your doctor can determine what will be a wise course of treatment. Consider tms for pain. ...Read more

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Can you take amitriptyline 75mg a day with a low dose of tramadol for pain?

Usually: While it is generally safe to use the medications in combination, there is a slight risk of developing serotonin syndrome. Serotonin syndrome is characterized by restlessness, diarrhea, rapid heart beat, confusion, sweating/fever, nausea/vomiting, loss of coordination, and blood pressure changes. In addition both can sedate you so you should be careful about driving. ...Read more

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I am on a low dose of tramadol. 50-100mg per day. Is it still safe to have alcohol ? Just stopped taking amitriptyline last week. 10mg per day.

I am on a low dose of tramadol. 50-100mg per day. Is it still safe to have alcohol ? Just stopped taking amitriptyline last week. 10mg per day.

Not recommended: Tramadol and alcohol are depressant of the central nervous system. Mixing tramadol with alcohol could lead to drowsiness to severe depression of brain activity, coma, and ultimately death. Tramadol has a prolonged half-life about 7 hours. It is still in your system for at least 10 hours. Is not recommended. ...Read more

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I have been prescribed amitriptyline 100mg for back pain is it ok to take it with tramadol 300mg?

I have been prescribed amitriptyline 100mg for back pain is it ok to take it with tramadol 300mg?

Drug interaction: It is not recommended to mix tramadol with antidepressants such as Amitriptyline due to increased risk of developing serotonin syndrome which can be a life threatening conditions. Please talk to your doctor before taking these medications together. ...Read more

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Can i mix tramadol and amitriptyline? My urologist gave them to me for cystitis in my bladder and i take 200mg of tramadol a day and 1 100mg of the other medicine at night, is it still okay to take both?

Medication effects: Amitriptyline is medication for Depression. Thank you for informing about use of Xanax (alprazolam). Using amitriptyline with Xanax (alprazolam) may increase dizziness, confusion, impairment in thinking, judgment, and motor coordination. See your Psychiatrist to discuss Diagnosis of anxiety, depression interaction of Amitriptyline and Xanax (alprazolam), benefits and side effects, decreasing the dose, and Therapy for stresses in life. ...Read more

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My Dr prescribed me tramadol and flexarol, at bedtime I have pills I take daily as wel(elavil&mavik). Last night I was very lightheaded and felt sick.

My Dr prescribed me tramadol and flexarol, at bedtime I have pills I take daily as wel(elavil&mavik). Last night I was very lightheaded and felt sick.

Sedating medications: Elavil (amitriptylene), tramadol, and Flexeril (cyclobenzaprine) are all sedating and if taken together in someone who's not used to them could indeed make you feel ill. The Mavik (trandolapril) is a blood pressure medication which is not sedating and is not culpable here. Both tramadol and Flexeril are as-needed meds, so it is safe to reduce your own dose of these by dividing the tablets and taking 1/2. ...Read more

Dr. Heidi Fowler
306 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


Tramadol (Definition)

A synthetic analgesic for treatment of ...Read more