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Doctor insights on: Is It Ok To Switch From Zoloft To Wellbutrin

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Dr. Alan Ali
778 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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Is it ok to switch from Zoloft to wellbutrin (bupropion) without tapering? because im a nervous wreck!

Is it ok to switch from Zoloft to wellbutrin (bupropion) without tapering? because im a nervous wreck!

That depends on dose: If you were on a really low dose - it is probably fine. But if on a higher dose, you may need to taper off of zoloft (sertraline) to prevent discontinuation syndrome. ...Read more

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Can i switch from Zoloft to wellbutrin (bupropion)?

Can i switch from Zoloft to wellbutrin (bupropion)?

Switch to Zoloft (sertraline): If limited response & as directed by your prescribing doc. ...Read more

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How we can safetly switch from the combo (100 mg ZOLOFT + 150 mg WELLBUTRIN (bupropion) XL) daily to the combo (50 mg ZOLOFT + 300 mg WELLBUTRIN (bupropion) XL) daily ?

How we can safetly switch from the combo (100 mg ZOLOFT + 150 mg WELLBUTRIN (bupropion) XL) daily to the combo (50 mg ZOLOFT + 300 mg WELLBUTRIN (bupropion) XL) daily ?

Who are 'We'?: Is one of the 'We' your Dr? If not - it should be. And then, your Dr is the one to take responsibility for this transition. Psych meds are not a good DIY project. Find professional guidance. Best! ...Read more

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I took my last 10mg Buspar (buspirone) 24 hours ago im being switched to Zoloft 50mg with Wellbutrin XL 150 is it safe to start Zoloft now? Or wait a day?

I took my last 10mg Buspar (buspirone) 24 hours ago im being switched to Zoloft 50mg with Wellbutrin XL 150 is it safe to start Zoloft now? Or wait a day?

YES: Should not be a problem beginning the Zoloft but I imagine your doctor let you know the regimen to change over. Buspar (buspirone) and Zoloft can be taken together typically as they affect serotonin in different ways. ...Read more

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I'm on 150 mg of wellbutrin (bupropion) and 50 mg of zoloft. I accidently took 2 pills of the wellbutrin (bupropion) so now I have 300 mg sr in me. Is this ok?

I'm on 150 mg of wellbutrin (bupropion) and 50 mg of zoloft. I accidently took 2 pills of the wellbutrin (bupropion) so now I have 300 mg sr in me. Is this ok?

Wellbutrin (bupropion) dose?: U should not change the dose of u medication without checking with u prescribing provider. If u took them accidently , that would be ok. ...Read more

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What effect can weed have on wellbutrin (bupropion) and zoloft?

Probably not good.: A fully informed answer can't be given, if only because "weed" is not standardized in the way that Wellbutrin (bupropion) and Zoloft are. But the concerns are: direct or indirect interference with the pharmacodynamics and phramcokinetics of the medicines; continuation of the underlying problems by virtue of avoidance or addiction. On the other hand, some people use it and still benefit from the meds ...Read more

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What the good dose of wellbutrin (bupropion) XL to add to Zoloft 50mg?

Variable.: That is very individual. If there is an atypical component to depression - I usually start with wellbutrin (bupropion) SR 100mg and increase dose by about 50mg every four days - titrate to response and side effects. I switch over to wellbutrin (bupropion) XL - after we have reached goal dose. ...Read more

Dr. Heidi Fowler
1,067 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more