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Doctor insights on: Is It Ok To Combine Prozac And Tramadol

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Can you take tramadol while on prozac (fluoxetine)?

Can you take tramadol while on prozac (fluoxetine)?

Tramadol &prozac: No you can not take them together as it can cause serotonin syndrome which is serious and potentialy fatal due to hyper stimulation of 5 ht1a recepters. ...Read more

Dr. Heidi Fowler
1,057 doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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Would it be fine to take 40 mg of Prozac (fluoxetine) along with 50 mg of tramadol 4 x/day?

Would it be fine to take 40 mg of Prozac (fluoxetine) along with 50 mg of tramadol 4 x/day?

Maybe: If you have been taking these for a while, you should be okay. But taking together new can have sedative effects not to mention other meds that can interact with these meds. Be careful and check with your pcp about other meds you could take. ...Read more

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I only took it for 3 days, so how long will it stay in my system. Prozac (fluoxetine) 20 mg. Also, can I safely take my tramadol?

I only took it for 3 days, so how long will it stay in my system. Prozac (fluoxetine) 20 mg. Also, can I safely take my tramadol?

Prozac (fluoxetine): Prozac (fluoxetine)'s half-life is up to 6-7 days but if you only took 3 doses, you didn't get much into you system. Trauma sol interacts with Prozac (fluoxetine) like drugs. It can increase the risk for the serotonin syndrome. If you are off Prozac (fluoxetine) 3 days you should be able to take tramadol. It is unlikely it would occur at your dose and duration ...Read more

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I only take 1 to 2 Tramadol aday. Was on Prozac (fluoxetine) only 3 days. Can I continue with my Tramadol. I took last Prozac (fluoxetine) mon @ 4:30pm?

I only take 1 to 2 Tramadol aday. Was on Prozac (fluoxetine) only 3 days. Can I continue with my Tramadol. I took last Prozac (fluoxetine) mon @ 4:30pm?

Of course : Tramadol is a rather unique analgesic drug that is indicated for moderate to moderately severe pain. Although it binds to mu receptors, tramadol is not technically classified as an opioid analgesic. Always tell your doctor if you’ve stopped taking any of your medications. ...Read more

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Can tramadol help with anxity and depression instead of taking zoloft, (sertraline) Prozac ect.

Can tramadol help with anxity and depression instead of taking zoloft, (sertraline) Prozac ect.

Tramadol: Tramadol is a pain killer. Zoloft (sertraline) or Prozac are anti-depressants. They are different classes of medications. Please discuss it further with your doctor before taking tramadol for depression or anxiety. ...Read more

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Was rxed tramadol for chest pains at ER yesterday. I stopped taking Prozac (fluoxetine) over 2 weeks ago.would I still be at risk for serotonin syndrome or seizure?

Was rxed tramadol for chest pains at ER yesterday. I stopped taking Prozac (fluoxetine) over 2 weeks ago.would I still be at risk for serotonin syndrome or seizure?

Not likely: Prozac (fluoxetine) usually clears from the body by two weeks. You are not likely to experience serotonin syndrome at this time. Tramadol by itself, however, can lower the seizure threshold making you at risk to have a seizure. If you are not taking it on an ongoing basis, you are safe. Hope this helps. Best wishes! ...Read more

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Hello! I take Prozac, daily .........my PCP & Surgeon are aware of all this........YET, FOR APPX THE LAST 3 & HALF YEARS THEY HAVE PERSCRIBED TRAMAD?

Hello!  I take Prozac, daily .........my PCP & Surgeon are aware of all this........YET, FOR APPX THE LAST 3 & HALF YEARS THEY HAVE PERSCRIBED TRAMAD?

Understood.: Although the combination of Tramadol (Tramad) & Prozac has the potential to cause a serotinin syndrome — it doesn't in most people. I have seen a couple of cases where a person was on a high dose of a selective serotonin reuptake inhibitor (SSRI) and tramadol & developed serotonin syndrome. Sometimes, it is not dose related. It is not uncommon to prescribe medications that may have potential to ...Read more

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Why do drugs like Prozac (fluoxetine) and Ultram that affect serotonin cause you to sweat more? How can I deal with the sweating better?

Why do drugs like Prozac (fluoxetine) and Ultram that affect serotonin cause you to sweat more? How can I deal with the sweating better?

Stop the combination: Serotonin syndrome when the two medications are taken together. Serotonin syndrome can be serious and even life threatening. It is the result of high levels of serotonin in the body. Serotonin syndrome is characterized by having at least three of these listed symptoms: tremor, shivering, agitation, diaphoresis fever, hyper-reflexia incoordination or myoclonus. Stop taken the two madication together. ...Read more

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Does Prozac (fluoxetine) cause Ultram to work better? I saw that Prozac (fluoxetine) increases opiod receptors in brain. Have back pain, osteoarthritis pain, foot nerve damage.

Unlikely: No evidence I know of that and there are significant interactions. Though interactions are the same there is evidence that Cymbalta (duloxetine) may help with chronic pain. Talk to your doctor about all the medications you are on and he/she can help you weigh the benefit vs risk of such combinations. ...Read more

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Why do some of your doctors say it’s ok to take tramadol and fluoxetine together - and some don’t ?

Serotonin syndrome: Tramadol has SNRI properties, so it is serotonergic. When combined with other serotonergic meds like fluoxetine, there is potential for serotonin syndrome. Depends on the doses, really, and the individual's tolerance to serotonergic agents. Some docs are more comfortable than other co-prescribing serotonergic drugs. I've safely co-prescribed these, but I've always been vigilant about monitoring. ...Read more

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How much space in between tramadol and fluoxetine is safe on a daily basis ?

No space needed: Ok to take together from a medication stand point. Your body can tolerate several meds at once. If you find it makes you sleepy take the fluoxetine at bedtime and the tramadol during the day if your pain is worse during the day. ...Read more

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On fluoxetine & tramadol adviced by doc. Leaflet said this isn't safe. What are risks of taking these together is it serious & should I stop taking one?

Glad you asked: Yes — these are risky in combo and the worst is very serious indeed. Serotonin syndrome can be deadly — it's rare to be that bad, but it happens. BUT, if you've started this, please get a Dr to monitor your coming off — stopping these abruptly can also be very risky. I wish more people would ask — and before they start the Rx! A good Dr is worth finding even if it takes time. Interview them! ...Read more

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Is it safe to take gabapentin, ibuprofen, lorazepam, fluoxetine, paracetamol and tramadol together?

Is it safe to take gabapentin, ibuprofen, lorazepam, fluoxetine, paracetamol and tramadol together?

Not unusual: There are several categories of medications that are used for the treatment of chronic pain. Unfortunately, for many patients, the long list of medications is not producing the intended or expected result and frustrating. See a pain management doctor for chronic pain management. ...Read more

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What is the side effects from taking Ultram and prosac together?

What is the side effects from taking Ultram and prosac together?

Drug interaction: It is not recommended to mix tramadol with antidepressants such as Prozac (fluoxetine) due to increased risk of developing serotonin syndrome. Please talk to your doctor before taking these medications together. ...Read more

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My daughter is currently taking Prozac(10mg), she has now been prescribed Concerta (18mg). Is it ok to combine these two medications. She is 14?

My daughter is currently taking Prozac(10mg), she has now been prescribed Concerta (18mg).  Is it ok to combine these two medications. She is 14?

Same Dr for Rx's?: There is an increased risk of some serious Prozac (fluoxetine) side effects so there needs to be coordination and dose adjustment if needed. Always be sure each Dr is fully aware of all other Rx's. Please do consider a good adolescent psychologist for best outcomes too. Therapy improves effects and lessens need for drugs. ...Read more

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Why is it not ok to suddenly withdrawing Prozac (fluoxetine)? I'm just wondering.

Prozac (fluoxetine) Withdrawal: Prozac (fluoxetine) is used to treat Major depressive disorder, Obsessive-compulsive disorder and Panic disorder.
It is not ok to suddenly withdrawing Prozac (fluoxetine) due to Withdrawal symptoms which can be:
? Anxiety
? Fatigue
? Nightmares
? Trouble sleeping
? Depression and mood swings
? Loss of coordination
? Muscle spasms
? Dizziness
See a Psychiatrist for Therapy and monitoring of symptoms and Prozac (fluoxetine). ...Read more

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I'm taking Prozac (fluoxetine) and have OCD. Is this ok if I slept for almost 15 hours?

Prozac (fluoxetine): It generally takes higher doses of ssri's to treat ocd, such as 60 to 80mg of prozac (fluoxetine). Are you asking whether prozac (fluoxetine) can cause you to sleep 15 hours or whether this is a symptom of your ocd? Please clarify ...Read more

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Is it ok to take spirulina and/or chlorella along with prozac (fluoxetine)? (40mg/daily)

Is it ok to take spirulina and/or chlorella along with prozac (fluoxetine)? (40mg/daily)

Yes -- ok: There are no interactions between spirulina or chlorella and prozac (fluoxetine). But, you need to investigate the products you're considering using to be sure they are not contaminated with heavy metals. This is a common issue with some of these products. Stick with a reliable company that guarantees its products, explaining how it tests for these contaminants. ...Read more

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Is it ok to take trazodone now (10pm) if I have taken Prozac (fluoxetine) this morn (11am)?

YES: Yes. Of course, you want to take a specific amount. Check with your dr to be sure you don't take too much. Also, itsounds like the thing you're taking prozacfor may be keeping you awake. That's something you should be working on with your dr (therapist). Keep helpers informed. Things go better that way. ...Read more

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I take 30mg Prozac and 5mg Valium daily. Is it ok to use CBD (Cannabidiol) to help get off Valium? Any interactions?

I take 30mg Prozac and 5mg Valium daily. Is it ok to use CBD (Cannabidiol) to help get off Valium? Any interactions?

No: Is illegal in some states and is only medicinal in some states and recreational in few states. Consult with your psychiatrist for help getting off Valium ...Read more

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Is it ok to take siberian ginseng daily for people who are stressed. Are there any major interactions with ssris like prozac (fluoxetine)?

Is it ok to take siberian ginseng daily for people who are stressed. Are there any major interactions with ssris like prozac (fluoxetine)?

Could be some: I checked naturaldatabase. Com -- which says that siberian ginseng may inhibit both cytochrome p450 2d6 and 2d9. Prozac (fluoxetine) is metabolized by these same enzymes, so its metabolism could take longer, and build up in your system. These are potential interactions only, but you asked. Rhodiola rosea is another adaptogenic herb that may help depression. It has no interactions at all with prozac (fluoxetine). ...Read more

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My doc has upped my Prozac (fluoxetine) from 20 mg to 40 mg i work so I was scared to take the other 20 mg today I took it an hour ago is that ok am scared?

prozac (fluoxetine): It depends on your system, starting dose is 20mg, maximum dose is 80mg, you can increase your slowly up if your sxs are not bester with small dose. ...Read more

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My doc took me off Prozac (fluoxetine) and put me on 75 mg effexox I took one last night and have felt bad all day is that normal is it ok if I don't take no more?

Hang in: It takes time for Effexor (venlafaxine) to start to work & for the previous medicine to get out of your system--it will take time to see what Effexor (venlafaxine) will do for you. ...Read more

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Is it ok to take Prozac (fluoxetine) at bedtime?

Is it ok to take Prozac (fluoxetine) at bedtime?

Depends on you: The timing doesn't change the effect of Prozac (fluoxetine) on depression, anxiety, or panic attacks. But Prozac tends to be "activating" and might disturb sleep if taken at bedtime. Most patients take it after their first food of the day, e.g., after breakfast. Rarely, patients find it sedating instead of activating, and then it's best to take it at bedtime. ...Read more

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Is it ok to take Prozac (fluoxetine) and levofloxin together?

Is it ok to take Prozac (fluoxetine) and levofloxin together?

DON' T: No contraindications but as a general rule, try taking any antibiotics or short term medication by itself to prevent interactions with other meds which may also make it less efficacious. ...Read more

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Is it ok to take relora along with prozac (fluoxetine)?

Is it ok to take relora along with prozac (fluoxetine)?

Moderate interaction: Relora contains magnolia and phellodendron extracts, as well as multiple vitamins (thiamine, riboflavin, niacin, b12, folate, (folic acid) etc). The magnolia has some CNS depressant properties which could combine with Prozac to create drowsiness & sedation. Without the prozac, there are studies showing positive results in stress-related eating: http://tinyurl. Com/l34ffm8 please discuss with your own doctor. ...Read more

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Is it ok to take propranolol with prozac (fluoxetine)? Propranolol is 10mg, Prozac (fluoxetine) is 20mg

Is it ok to take propranolol with prozac (fluoxetine)? Propranolol is 10mg, Prozac (fluoxetine) is 20mg

Yes: Taking both could increase the effect of propranolol. The Propranolol dose you are taking is really low, so probably no need to worry about hypotension effects or heart rate being too slow. ...Read more

Dr. Alan Ali
778 doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more


Tramadol (Definition)

A synthetic analgesic for treatment of ...Read more