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Doctor insights on: Is It Likely That I Have Ms If My Spinal Tap Is Completely Negative

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Is it likely that I have MS if my spinal tap is completely negative?

Is it likely that I have MS if my spinal tap is completely negative?

Possible: Each test has a false negative and false positive rate. Some better than others. While you may be able to diagnose MS by spinal tab, that is usually positive a little more than 80% of the time. This means some who do have it might test negative. A brain MRI is positive in more than 95% of cases. If you are still having symptoms of ms, see your doctor to consider an mri. ...Read more

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Dr. Bennett Machanic
1,421 doctors shared insights

Multiple Sclerosis (Definition)

Multiple sclerosis is a progressive disease that interferes with the functioning of the central nervous system and brain. Symptoms include numbness, impairment of speech and of muscular coordination, blurred ...Read more


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I had a spinal puncture done and the results said CSF/serum oligoclonal bands negative and CSF Oligoclonal bands 0 bands. does that mean i have ms?

Multiple sclerosis: Presence of CSF oligoclonal bands is consistent and normally diagnostic of multiple sclerosis in the right circumstances. The absence does not rule out MS and the diagnosis has to be based on clinical findings and MRI results. There may also be some ethnic differentiation of oligoclonal bands present in patients with MS. you can review the article below http://dx.doi.org/10.1155/2015/217961 ...Read more

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How else will a neurologist find if I have ms? I've had a negative brain, spinal, and cervical MRI, as well as blood tests. Having neuropathy symptoms

How else will a neurologist find if I have ms? I've had a negative brain, spinal, and cervical MRI, as well as blood tests. Having neuropathy symptoms

Spinal tap: If there are signs suggesting a demyelination process, then in the spinal fluid will be a myelin basic protein or other product of the breakdown of myelin, the coating around the nerves. Yes I know the tap is not pleasant but in the absence of a diagnosis it may be necessary . Good luck ...Read more

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My neuro thinks that i have ms and has told me to get a lumbar puncture. if that comes back as not indicating ms, what happens after that?

Hard to say...: I'm sorry, but this isn't something any distant forum doctor can answer. It depends on information you don't provide, including your symptoms, neurological examination, and perhaps things like CT scan or MRI, if these were done. The obvious person to ask is your neurologist. In any case, I suggest crossing that bridge if and when you come to it. Good luck! ...Read more

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I have ms, spinal lesions, legs immobile. Now losing ability to sit up without great spastic pain and weakness. Why can't i sit up in a chair ?

I have ms, spinal lesions, legs immobile.  Now losing ability to sit up without great spastic pain and weakness. Why can't i sit up in a chair ?

Complex: The above describes a high burden of disease, and the loss of strength with increasing weakness and spasticity may represent a spinal cord relapse. But, consider a urinary tract infection or metabolic imbalance as a triggering event. This needs to be addressed asap, and fully sorted out. Is your current medication effective enough? Do you need steroids or acth? See your neurologist soon. ...Read more

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I have MS and spinal stenosis. Emg shows l5-l4-s1 compression of nerve root. Orthopaedic surgeon won't do the surgery without neurologist ok.?

I have MS and spinal stenosis. Emg shows l5-l4-s1 compression of nerve root. Orthopaedic surgeon won't do the surgery without neurologist ok.?

Cautious : I would guess the surgeon is being cautious to make sure that the neurologist agrees that surgery will help the problem. Stenosis of the spinal canal is different than neuroforaminal stenosis. Emg is usually normal in canal stenosis and is sometimes helpful in neuroforaminal stenosis. Just because you have something wrong on EMG and MRI doesn't mean surgery is the answer. Ask twice, cut once. ...Read more

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What does it mean if my spinal tap , for MS came back negative?

NONSPECIFIC: Although spinal fluid analysis can help confirm the diagnosis, it is sometimes misleading. The best data involves oligoclonal bands, and these may be absent in 50% of early ms pts, and 25% in more advanced cases. If you do have ms, absence suggests more benign course. Suggest followup mri's over next few months, as changes can help diagnose. Meds are best started asap, follow doc's advice. ...Read more

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4 years ago tested neg for ms with mri and spinal tap. Have a lot of ms symptoms. Whats the chances if it being pos now after 4 yrs?

4 years ago tested neg for ms with mri and spinal tap. Have a lot of ms symptoms. Whats the chances if it being pos now after 4 yrs?

Multiple sclerosis: You need to see a neurologist and be fully assessed. This disease can appear within a 4 year hiatus from your last exam. On the other hand it would be a little unusual and you may be having some other issues causing your anxiety. Please be seen and fully evaluated. Good luck. ...Read more

Dr. Dariush Saghafi
372 doctors shared insights

Lumbar Puncture (Definition)

To test for meningitis or multiple sclerosis or a variety of problems, a small needle is inserted into the lumbosacral cistern to obtain spinal fluid for testing ...Read more