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Doctor insights on: Is It Dangerous To Take Lorazepam With Tramadol For Pain And Depression

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Dr. Pamela Pappas
4,598 Doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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How much ativan (lorazepam) could cause dangerous resp. Depression in a 5'5" 138lb male. Got prescription for 1mg tabs, scared to take them.

How much ativan (lorazepam) could cause dangerous resp. Depression in a 5'5" 138lb male. Got prescription for 1mg tabs, scared to take them.

It's ok: 1 mg every 6 hours is safe. You can always cut the tablet in half and start with a lower dose to see how it will affect you. You will not have any respiratory depression at 1 mg dosage though. ...Read more

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Is it ok to take my Ativan (lorazepam) for anxiety when I need it if I've been recently also been dealing with some depression?

Is it ok to take my Ativan (lorazepam) for anxiety when I need it if I've been recently also been dealing with some depression?

Check in..: Ativan (lorazepam) is commonly given for anxiety to be taken regularly and/or "as needed." Should be fine, but suggest you check with your prescribing doctor, who knows you best, to clarify directions and also to let him/her know about any recent depression. ...Read more

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Can I take 1 aspirin, if I have a hedacke? I also have OCD and depression, so I take 3 Prozac (fluoxetine) and 1 Lorazepam. Is this ok?

Can I take 1 aspirin, if I have a hedacke? I also have OCD and depression, so I take 3 Prozac (fluoxetine) and 1 Lorazepam. Is this ok?

Drug interactions.: Although taking aspirin with prozac (fluoxetine) can increase risk of bleeding - that is more so with renal/ liver disease or in elderly. Taking one aspirin is not likely to cause a problem. ...Read more

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I take 120 mg of Cymbalta (duloxetine) daily for severe depression. I appear to have more anxiety now, I am also taking 3mg Lorazepam a day. What are the risks?

I take 120 mg of Cymbalta (duloxetine) daily for severe depression. I appear to have more anxiety now, I am also taking 3mg Lorazepam a day. What are the risks?

Risks: Two important items:
1: You MUST see your Primary doctor!
2: You MUST also see a Psychologist to help you with your anxiety

Tough times but you will be carefully controlled by both doctors. Please keep me posted. ...Read more

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I took 100mg of tramadol at 430 p.M. Is it ok 2 take. 5 mg of ativan (lorazepam) at 11 p.M.

I took 100mg of tramadol at 430 p.M. Is it ok 2 take. 5 mg of ativan (lorazepam) at 11 p.M.

Yes: Tramadol and Ativan (lorazepam) do not interact. They both can cause somnolence (tiredness), so you need to be careful not to take both and become a zombie. If you are taking both of these medications on your own, I suggest you consult with your doctor. There may be more optimal ways to treat pain or anxiety. ...Read more

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Can I take Tramadol for treating depression?

Can I take Tramadol for treating depression?

Not recommended: Tramadol is a rather unique analgesic drug that is indicated for moderate to moderately severe pain. Although it binds to mu receptors, tramadol is not technically classified as an opioid analgesic. Instead, it is classified as a centrally acting synthetic analgesic compound and therefore is not a scheduled narcotic drug. Not used for depression. Consult with your PCP for more information. ...Read more

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Can I take ativan (lorazepam) with tramadol?

Can I take ativan (lorazepam) with tramadol?

Only: Only if your dr prescribed it this way. They may potentiate side effects; you should consult your dr before. Best of luck. ...Read more

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Can I try 5 HTP in morning for depression if I take a 50mg of Tramadol in early afternoon? Thank you.

Can I try 5 HTP in morning for depression if I take a 50mg of Tramadol in early afternoon? Thank you.

No! - Advise against: There's a serious interaction of increased risk of serotonin syndrome and that's not a good thing. "Trying" to find ways to feel better is a wonderful idea. But the ways that involve powerful chemicals are not for D.I.Y. (I'm not comfortable even when pros do it.) Search for changes in daily/social routines, scenes. Consider a new leisure activity, etc. Therapy support can really help. Be careful! ...Read more

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Is it ok to take tramadol and ativan (lorazepam) in combination for pain and muscle tension?

Is it ok to take tramadol and ativan (lorazepam) in combination for pain and muscle tension?

Talk to your doctor: There is a potential interaction between these two medications. You can experience drowsiness, dizziness and difficulty concentrating. Ref: Drug Interactions Checker on Drugs. Com. Talk to your doctor about risks, benefits and side effects of your medicine. Don't drink alcohol and don't drive if you experience drowsiness on your medicine. Be safe! ...Read more

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I take vyanasse and viibryd went my depression gets bad my joints ache and I don't sleep someone suggested tramadol how do I suggest this to my psych?

I take vyanasse and viibryd went my depression gets bad my joints ache and I don't sleep someone suggested tramadol how do I suggest this to my psych?

I don't know if I: Would want to prescribe that combo because of increased risk of serotonin syndrome, seizures and symptoms like jitteriness, nervousness, anxiety, restlessness, & racing thoughts. See Drugs. Com drug interaction checker. Discuss your achy joints with your doctor. Consider a non-controlled substance. ...Read more

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I am on Zoloft (sertraline) for depression. Can I take a 50 mg tramadol for my broken foot?

I am on Zoloft (sertraline) for depression. Can I take a 50 mg tramadol for my broken foot?

Bad combination.: Adding Tramadol to any serotonin-reputake-inhibiting medication like Zoloft (sertraline) can lead to a very dangerous condition called serotonin syndrome. This combination is ill-advised. ...Read more

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Is it safe to take gabapentin, ibuprofen, lorazepam, fluoxetine, paracetamol and tramadol together?

Is it safe to take gabapentin, ibuprofen, lorazepam, fluoxetine, paracetamol and tramadol together?

Not unusual: There are several categories of medications that are used for the treatment of chronic pain. Unfortunately, for many patients, the long list of medications is not producing the intended or expected result and frustrating. See a pain management doctor for chronic pain management. ...Read more

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Is ativan (lorazepam) used for depression?

Is ativan (lorazepam) used for depression?

No: Ativan (lorazepam) is a benzodiazepine usually used for the treatment of anxiety. It may also be used to help with the anxiety symptoms sometimes associated with depression. ...Read more

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Can lorazepam cause depression?

Can lorazepam cause depression?

Yes: Lorazepam is an anti-anxiety drug that is in the Valium (diazepam) family. It is short acting (about six hours, and when taken regularly for prolonged periods will lead to dependency, which means sudden cessation will lead to serious withdrawal sx, similar to alcohol withdrawal. Both alcohol and diazepams can lead to depression. You must see the prescriber, often ur gp, every 1-3 mos to monitor. ...Read more

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Can OCD or depression treated with Prozac (fluoxetine) and Lorazepam cause forgottnes?

Lorazepam can: Cause forgetfulness & difficulty concentrating. Call your prescribing physician if the side effects impair your daily functioning. Make a list of all prescription & over-the-counter medicines you take, including vitamins, minerals & other dietary supplements. Keep this list with you for all medical & therapy visits & in case you ever end up in the ER because of accident, injury or acute illness. ...Read more

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How do I treat my anxiety depression and insomnia? I have been on ativan (lorazepam) for 14 years and its doing nothing

How do I treat my anxiety depression and insomnia? I have been on ativan (lorazepam) for 14 years and its doing nothing

See a psychiatrist: Insomnia, anxiety and depression often go hand-in-hand. See a psychiatrist for evaluation and treatment with medication or with cognitive behavioral therapies. ...Read more

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I've had panic disorder and depression for 22 years. It's been getting worse lately. I've been on Prozac and lorazepam all this time. What can I do?

I've had panic disorder and depression for 22 years. It's been getting worse lately. I've been on Prozac and lorazepam all this time. What can I do?

Let your prescribing: Provider know. Add in non-pharmacologic treatments. Cognitive Behavioral therapy can be effective. Aim for daily exercise, 8 hrs sleep /night & good nutrition w 5 servings of veggies & 4 of fruit per day. Try tai chi, yoga, Qi Gong, progressive muscle relaxation, deep breathing exercises or meditation. Take care. ...Read more

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Have gad/depression. Took Paxil (paroxetine) 10mg for 1 week, 20mg for the last 2.5. I'm not sad, but I'm not happy, and still somewhat anxious- taking lorazepam prn. How do I know if the dose should be increased?

Have gad/depression. Took Paxil (paroxetine) 10mg for 1 week, 20mg for the last 2.5. I'm not sad, but I'm not happy, and still somewhat anxious- taking lorazepam prn. How do I know if the dose should be increased?

Only Time will tell: Treatment of anxiety disorders with ssris takes longer and higher doses for most people than does depression. While 20 mg is toward the low end for anxiety, best to let is just work for another 1.5 weeks; if no change in mood or anxiety, then dosage increase is reasonable. If there is improvement in either in 10 days, then sit tight and watch for another ten-14 days. Gentleness is the key. ...Read more

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Can OCD and major depression disorder treated with Prozac (fluoxetine) and Lorazepam, cause halucinations?

Can OCD and major depression disorder treated with Prozac (fluoxetine) and Lorazepam, cause halucinations?

NOT USUALLY: Hallucinations are typically an indication of a psychotic process or maybe less serious if it happens upon falling asleep or waking up. OCD does not involve hallucinations as a symptom. Antidepressants do not typically cause hallucinations either. If the is some connection then the diagnosis may need to be reconsider like possibly bipolar disorder. Speak with your doctor. ...Read more

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Is it severe if I have OCD, major depression disorder treated with Lorazepam and Prozac (fluoxetine) and I'm cutting myself and thinking about suicide?

Is it severe if I have OCD, major depression disorder treated with Lorazepam and Prozac (fluoxetine) and I'm cutting myself and thinking about suicide?

Get help now.: This is serious. If you are having thoughts about killing yourself, please be seen at the nearest emergency room now. Have a friend or relative drive you. If need be, you can call 911 for emergency services & they can provide transport. You can call the National Suicide hotline 24/7 at 1-800-273-8255. Consider dialectica Behavioral therapy. ...Read more

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taking 6oomg tegretol, 10 mg of Lexapro, (escitalopram)25 mg of trazodone and 1.5 lorazepam for ocd/mood swings. Still have depression. Is this a strange combination?

taking 6oomg tegretol, 10 mg of Lexapro, (escitalopram)25 mg of trazodone and 1.5 lorazepam for ocd/mood swings. Still have depression. Is this a strange combination?

Not common: Discuss with prescribing doc and consider second opinion. I would be happy to consult with you through my virtual practice if you are a resident of CA. If not you may be able to locate another psychiatrist with a virtual practice who is licensed in your state ...Read more

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Can ativan (lorazepam) increase the effects of tramadol?

Can ativan (lorazepam) increase the effects of tramadol?

Probably: Tramadol is used for pain relief and has less addiction risks than narcotics. Pain can cause anxiety and vise versa. I believe that ativan, (lorazepam) a benzodiazepine that decreases anxiety, can increase effects of tramadol. Reisk of abuse increase though! ...Read more

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Yes I was wondering if I can my tramadol and citalopram with lorazepam?

Yes I was wondering if I can my tramadol and citalopram with lorazepam?

Probably: Tramadol and Citalopram increase serotonin. If these were prescribed together it is likely your doctor will monitor you for serotonin syndrome. Tramadol and Lorazepam can have an effect on your central nervous system. Again, your doctor probably plans to monitor for this. ...Read more

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Is there a reaction between tramadol 50mg and lorazepam?

Possibly: The can both cause sedation and should only be taken together under medical supervision. ...Read more

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So its day 21 off tramadol starting to feel better after withdrawal, im on matazapine for depression, will I get better everyday?

So its day 21 off tramadol starting to feel better after withdrawal, im on matazapine for depression, will I get better everyday?

Tramadol withdrawal: Day 21 congratulations! The mental part will be the worst for you: sadness, depression, craving and anxiety. It can take some time before everything returns to normal, but everyone is different. You are almost there. Try getting an extra support form the AA meetings or from your doctor. Take care. ...Read more

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Is it ok to mix tramadol and lorazepam together like maybe two hours appart 25 mg of tramadol and. 5 of lorazepam?

Caution advised: Both prescribed to you, by the same doctor? Should be ok. Official answer: combo may increase risk of CNS [brain] and respspiratory depression, psychomotor impairment, coordination, driving risk. (additive effects). ...Read more

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Hi: want 2say ThankYou, firstly, 4your service. How much REALLY can tramadol affect my serotonin levels? Notice considerable help w/depression symptoms

Hi: want 2say ThankYou, firstly, 4your service. How much REALLY can tramadol affect my serotonin levels? Notice considerable help w/depression symptoms

Great question: And the honest answer is. .. No one is really sure, unfortunately. This is because circulating serotonin doesn't necessarily correlate with how you "feel" - it's very hard to determine. That said, tramadol does inhibit norepinephrine/serotonin reuptake. .. Which is how the pain signals from the body are translated in the brain. Hope that helps! ...Read more

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How in the heck does tramadol work for depression and anxiety I thought it was a pain reliever?

How in the heck does tramadol work for depression and anxiety I thought it was a pain reliever?

Unlikely: More likely to be a depressant in the long run - on the short run may give relief and so look like an antidepressant ...Read more

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I've tramadol for bursitus pain. It makes me happy&calm, different from normal because of my severe Anxiety&Depression. Can I stay on it to treat A&D?

Anxiety, Depression: I understand your need for relief of Bursitis pain.
It can give sense of Euphoria which you like.
Tramadol can cause Anxiety and Depression which can also be due to stress of relationship with parents, siblings, friends, separation, school and identity; they can become worse with use of alcohol and drugs.
See a Psychiatrist for Diagnosis, Therapy.
See an Orthopedic physician for Bursitis. ...Read more

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I am71yrs old the doctor prescribed 0.5mg Lorazepam twice a day - am I safe having them with 10mg of temazepam at night and tramadol 50mg 3timesa day?

I am71yrs old the doctor prescribed 0.5mg Lorazepam twice a day - am I safe having them with 10mg of temazepam at night and tramadol 50mg 3timesa day?

Check meds: Temazepam is dispensed in 15 mg or 30 mg. Please recheck your meds. Should be ok, but do not drive or operate equip if you feel light headed. Both of these meds are addictive. There may be safer options.. ...Read more

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I was on tramadol for over 5 yrs for depression 800 mgs I stopped and began gabapentin to withdraw, I'm off all meds now over 6mths but unhappy unmotiv

I was on tramadol for over 5 yrs for depression 800 mgs I stopped and began gabapentin to withdraw, I'm off all meds now over 6mths but unhappy unmotiv

See a good therapist: A supportive psychotherapist can help you evaluate all of this and perhaps find things you can do to make life better. If different medication would help, you can explore it together to be careful about the effects. Give it some thought. ...Read more

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Can tramadol help with anxity and depression instead of taking zoloft, (sertraline) Prozac ect.

Tramadol: Tramadol is a pain killer. Zoloft (sertraline) or Prozac are anti-depressants. They are different classes of medications. Please discuss it further with your doctor before taking tramadol for depression or anxiety. ...Read more

Dr. James Hall
571 Doctors shared insights

Lorazepam (Definition)

A medication of some versatility, a benzodiazepam of brief duration, that can be employed to stop ongoing seizure activity, can be used to control anxiety, assist as a sleep aide, and employed by a ...Read more


Tramadol (Definition)

A synthetic analgesic for treatment of ...Read more