Doctor insights on:
Is It Bad Luck Or Bad Genes That Made Me Develop Cushing Disease
Not your fault: Quoting dr. Loh:primary cushing's syndrome is the result of an endocrine active mass of adrenal gland cells that become so not as a result of lifestyle habits (good or bad). It's not your fault, but fortunately often completely curable. There are secondary cushing's syndromes related to medications doctors give to treat certain conditions, and it becomes a balance of benefits vs. Risks. ...Read moreSee 1 more doctor answer
Cushing disease is excessive cortisol production due to an acth secreting pituitary adenoma. Acth stimulates the adrenals to produce excessive cortisol, leading to central obesity, lack of growth in children, high blood pressure, hyperglycemia, muscle weakness and skin fragility. It can also ...Read more
Both: Some of parathyroid tumors have no genetic bearing then you can call it bad luck, others hane genetic link as in men syndromes. ...Read more
Answer is complex: Avm are communications which in variable degrees exist in different parts of the body. Most are congenital (you are born with) others can be related to injury or trauma . It also depends how large the avm are and if they cause symptoms besides the esthetic concern. ...Read more
My mom was diagnosed with Pick disease but doing research I see it is similar to Lewy and CJD. Is the life expectancy similar. Worse because bad fall.
Archaic terminology: I presume your Mom has progressive cognitive decline, and statistical considerations would include Alzheimer's, vascular and mixed dementias, and perhaps Dementia with Lewy bodies. CJD is a prion infection, and relatively uncommon. You need a second opinion, as the diagnosis you expressed does NOT truly exist, as concepts have changed. ?Concierge or INBOX consult to expand on this? ...Read moreSee 1 more doctor answer
I'm suspecting that I have Crohn's disease after doing some research. Is this curable and how bad can it get?
Not curable: Crohn's disease is not curable but can be well managed with the right medications. There are lots of manifestations of crohn's including weight loss, anemia, abdominal pain, vomiting, bowel obstruction, malabsorption, and diarrhea. Crohn's is tricky to diagnose. Please consult your primary care doctor. ...Read moreSee 1 more doctor answer
Nothing genetic: I am not aware of any geneticly linked predisposition to ear drum rupture. The ear drum is tucked away in a strong bone protected from most outside events. Cupping injury( in a fight) or proximity to a blast might generate pressure waves that would rupture your drum. With any middle ear infection a rupture might occur & essentially all kids have them but not so many adults. ...Read moreSee 2 more doctor answers
Is it true that aspartam is bad for health ? Does it cause anything like cancer or ... ? What is a better substitute ?
Aspartame: It is safe and fda gave them "gras" status meaning generally recognized as safe". No clear cut link to cancer except the saccharin studies of 70, s raising concern for bladder cancer in rats but nothing has panned out since then and generally there consumption is safe like "equal" and "nutrasweet". ...Read more
My mother died in 1997 of a horrible disease called my cancer is it in my genes to and is it possible that I'm gonna die of it too ?
Sorry to hear: If you are asking "can I ever have cancer?", the answer is yes, just as any one can. If you are worried about increased risk due to your mom, it depends on many factors. At your age cancer is rare but I suggest you discuss this with your doc. He/she will review your personal and family history and make recommendations for you. ...Read moreSee 1 more doctor answer
Depends: Liposarcoma falls in the category of sarcoma which are connective tissue cancers. Prognosis depends on staging, size of the tumor, aggressiveness of the tumor( grade), location. Low grade tumors that are completely excised with clear margins without evidence of spread elsewhere, have a very good prognosis. ...Read more
Fatal LEIGH;S DISEAS: It is fatal leighs disease which trikes quickly and is fatal. ...Read more
If i clear high risk hpv, what can it do to me when i'm old, like 70 or more, and my immune system isn't as good as it is now? Does it mean cancer?
Regular followup: That you have cleared a high risk strain of hpv for now is a good thing.However, once you have it it could return at any tome. Regular followup exams and testing by your doc will be your best plan.Hopefully, it will never produce cancer, but it certainly could at some point. ...Read more
Can a genetics defect called mthfr1 cause a lot of problems a gentics told me it does not is that true or not?
Can cause many probs: Mthfr mutations cause problems with methylation, a crucial process in every cell. Patients with these problems have increased incidence of depression, bipolar disorder, schizophrenia, autism, birth defects, heart disease, stroke & possibly cancer. However, those with just 1 mutation have much less risk than those with 2 copies of the mutation. See http://heal-thyself.Ning.Com/profiles/blogs/mthfr-1. ...Read more
How does a bad diet cause lack of appetite? Im 22 and my appetite just isnt as strong lately I've been fearing cancer but everybody is saying appetite loss is not a usual sifn of cancer true or false please explain in detail so I can understans fully?
No true, false here!: What is a bad diet? A good diet is balanced to carbohydtes, protein and fat, with fruits and vegetables. The amount as well as quality are important. Appetite loss can be a sign of many diseases. What is your weight? Any fatigue or fever, pain or... ? How are your emotional and psychlogical conditions? One has to open, hopeful, optismitic and not hypochondiac. Give us more details? See a dr. ...Read more
Can you tell me if a disease is genetic, does that mean that everyone with that disease is related?
No,it is from a gene: No, it means that the cause of the disease is from a gene. Sometimes, however, there are spontaneous mutations in the gene. Certain conditions, such as neurofibromatosis, have a very high spontaneous mutation rate, so there will be no family history of the disease prior to the affected patient. Because it is an autosomal dominant disease, any child will have a 50% chance of having the disease. ...Read more
Where did tay-sach originated from? From what organism or plant do people get this disease? I know this is a genetic disease but how did it become a genetic disease?
Human : Human genetic diseases arise because of mutations in the genetic information carried in the reproductive cells (eggs and sperm or the cells that make them). Genetic information is stored in the complex molecule called dna, which has properties that allow it to be copied, kind of like the way a computer disk can be copied. Dna contains information packed into functional units called genes, which behave like individual computer programs, and often create proteins that contribute to the machinery of the cells that make up our bodies. Just like the way the information on a computer disk can become corrupted when it is stored over time (imagine a cd or dvd exposed to sun, scratches, or dust) or when it is being copied, the information stored in dna can be corrupted either when stored or when copied. This is called a mutation. Some mutations can produce machinery that doesn't work at all, and some mutations produce machinery with properties that are different than those of the original gene. Tay sachs disease (also called hexosaminidase a deficiency) is caused by a mutation in the hexa gene that makes the machine (or enzyme) called hexosaminidase a. When it is not mutated, this enzyme helps to break down complicated sugar-like molecules in human cells. The mutation that causes tay sachs disease makes a non-working enzyme. The sugar-like molecules build up in cells, and lead to serious problems. (children with tay sachs disease may die by the age of 4.) every human cell has two copies of just about every gene. One copy is from the father, and one copy is from the mother. If you get a mutated hexa gene from one parent, and a normal hexa gene from the other parent, the normal gene will make working hexosasminidase a, and you will be able to break down those sugars... So you won't die... So you may live to pass your genes on to your children. When parent passes on genes to a child, only one of the two copies is passed. (if this didn't happen, then each generation would have twice as many genes as their parents.) so, a parent with one good copy and one bad copy of a gene, has about a 50:50 chance of passing the bad gene on to a child. To get tay sachs disease, a child has to get two bad copies of the hexa gene. One from each parent. ...Read moreSee 1 more doctor answer