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Doctor insights on: Is History Of Gallstones A Symptom Of Intrahepatic Cholestasis Of Pregnancy

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What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

Cholestasis: You could elevated bilirrubin and alkaline phosphatase predominantly. Others sucn as transaminases can be elevated too. They will all normalize upon delivery. ...Read more

Previous Gallstones (Definition)

Gallstones occur in nearly 25% of women in the U.S. by age 60, and as many as 50% by age 75. In most cases, they have no symptoms. In general, women are probably at increased risk because estrogen stimulates the liver to remove more cholesterol from blood and divert it into the bile. Pregnancy increases the risk for gallstones, and pregnant women with stones are more likely to have symptoms than nonpregnant women. Surgery should be delayed until after delivery if possible. In fact, gallstones may disappear after delivery. If surgery is necessary, laparoscopy ...Read more


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What are the causes of a fatty liver of pregnancy?

What are the causes of a fatty liver of pregnancy?

Enzyme deficiency: The association of cases of acute fatty liver of pregnancy with one of the inherited defects in mitochondrial beta-oxidation of fatty acids (the acronym for which is lchad), suggests that some affected women and their fetuses might have an inherited enzyme deficiency in beta-oxidation that predisposes the mother to this disorder. ...Read more

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What is the early sign of carcinoma of pancrea?

What is the early sign of carcinoma of pancrea?

Signs/symptoms...: Pancreatic cancer is often diagnosed at a late stage since it rarely shows early symptoms. Symptoms include abdominal pain, painless jaundice (yellowing of eyes and skin), darkening of the urine, loss of appetite, nausea/vomiting, weight loss, and pale/grey stools. ...Read more

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How is cholestasis of pregnancy diagnosed?

History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. ...Read more

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What is the cause of a fatty liver in pregnancy?

What is the cause of a fatty liver in pregnancy?

Enzyme deficiency: The association of cases of acute fatty liver of pregnancy with one of the inherited defects in mitochondrial beta-oxidation of fatty acids (the acronym for which is lchad), suggests that some affected women and their fetuses might have an inherited enzyme deficiency in beta-oxidation that predisposes the mother to this disorder. ...Read more

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What are the signs of vaginal cancer? Is bloating of the abdomen a sign?

What are the signs of vaginal cancer? Is bloating of the abdomen a sign?

See below: Ulcer and or a mass in the vagina and abnormal vaginal bleeding are usual signs of vaginal cancer. Abdominal bloating is not likely, though bloating may be associated with ovarian lesions. See this site for more info on vaginal cancer. http://www.mayoclinic.com/health/vaginal-cancer/ds00812. ...Read more

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What are the early symptoms of a kidney stone?

What are the early symptoms of a kidney stone?

Abdominal pain: One may experience vague abdominal discomfort which may progress to being more persistent. Kidney stones are evaluate with urine tests, ultrasound or ct scan. ...Read more

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What are the chances a path report from a "brushing" of a liver bile duct during ercp is incorrect in a cancer dx? 87yo. Severe jaundice- no pain?

What are the chances a path report from a "brushing" of a liver bile duct during ercp  is incorrect in a cancer dx? 87yo. Severe jaundice- no pain?

Slight chance: Pathologists are experts for diagnosing cancer from a single cell , in order to do that must get an intact undamaged cell , must preserve it , properly store & label it and send to cyto-pathology lab , even in presence of ca brush may miss it, all of the above can happen then will false negative results , 85 - 90 % time will not happen , will have correct diagnosis , good luck to your dad. ...Read more

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What type of jaundice is associated with gallstones?

What type of jaundice is associated with gallstones?

Obstructive: Gallstones that pass from the gallbladder into the bile duct can cause obstructive jaundice. Often the gallstones will pass through on their own, others need to be removed by ERCP procedure with a gastroenterologist. ...Read more

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Is fatigue a symptom of angiodysplasia of the colon?

Is fatigue a symptom of angiodysplasia of the colon?

Unlikely : Only if you have been bleeding from it and a) have a low blood count or b) are iron deficient. Both require a blood test for diagnosis. ...Read more

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What are symptoms of a stone in bile duct?

What are symptoms of a stone in bile duct?

Varies: Some cause no symptoms. Others can be associated with right upper abdominal, flank, back or epigastric pain. Nausea and vomiting may occur especially if the stone blocks the bile duct and/or inflames the pancreas. You may notice yellowing of the eyes, darkened urine or light / clay colored stools. ...Read more

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Is intrahepatic cholestasis of pregnancy painful?

Is intrahepatic cholestasis of pregnancy painful?

NO: Cholestasis of pregnancy does not generally cause pain. The most common symptoms is pruritis (itching). It almost always starts with itching on the palms of the hands and soles of the feet, and it is first noticed at night. The itching spreads to other parts of the body over time. Treatment with ursodiol (bile salts) can improve symptoms. Consultation with a high risk OB is recommended. ...Read more

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What is the possible cause of high sgpt/sgot with no signs of jaundice or any sickness?

What is the possible cause of high sgpt/sgot with no signs of jaundice or any sickness?

Sot and sgpt shows c: Look for causes of obst jaundice or hemolysis first. Cell death isindicated by high SGOT sgpt. Get a bilirubin, alk phos and an ultrasoundfor starters along with a hepatitis profile. ...Read more

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What is the prevalence of miscarriage with no symptoms?

What is the prevalence of miscarriage with no symptoms?

Probably high: I have heard estimates as high as 75% of fertilizations do not result in pregnancies. The known miscarriage rate is 15 to 20%, suggesting that a lot of fertilized eggs pass through unnoticed. ...Read more

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Is excess of dandruff a possible symptom of cancer?

Is excess of dandruff a possible symptom of cancer?

No..: It could be a sign of allergy, malnutrition, or anxiety, but not cancer. If it's not responding to shampoos, see a dermatologist, who should be able to help. Good luck. ...Read more

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Why is a history of liver disease significant?

Why is a history of liver disease significant?

You might get it: History is a great way and very significant as the possiblity of genetic pattern though it is only 35% thereabout. ...Read more

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In cirrhosis does the presence of ascites always indicate decompensation and is this considered a serious complication and stage of the disease?

In cirrhosis does the presence of ascites always indicate decompensation and is this considered a serious complication and stage of the disease?

It is concerning: Ascites- buildup of fluid in the abdominal cavity- can be a sign of serious decompensation in the liver function. This is usually seen in the later stages of liver failure. If this is seen you should let your doctor know right away. This is associated with decreased survival. However if the cause of the liver damage is found early-& treated this can delay progression. Cirrhosis can't be undone. ...Read more

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What is the common initial sign of adenocarcinoma of the kidney?

What is the common initial sign of adenocarcinoma of the kidney?

Usually bleeding in: Blood in the urine is common if there is a cancer in the kidney. Sometimes it will cause pain in the flank or in the back. A simple urinalysis can often reveal blood cells which is a common tip off. To get further testing done. ...Read more

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What are the tests for intrahepatic cholestasis of pregnancy?

What are the tests for intrahepatic cholestasis of pregnancy?

LFTs, bile acids.: Liver function tests (alt/ast/alkaline phosphatase) and bile acids can clinch the clinical diagnosis of intrahepatic cholestasis of pregnancy - in the absence of cholelithiasis. ...Read more

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What are the symptoms of a gallstone attack?

What are the symptoms of a gallstone attack?

Biliary Colic: Gallbladder attacks cause a very classic constant, noncramping pressure like pain in the right upper abdomen or mid-abdomen. The pain often radiates around into the right back +/-shoulder; nausea+/-vomiting+/-fever+/-chills may occur, as well. Typically the pain is precipitated by food, especially fatty/fried ones. Typical attacks may last hour(s) and often resolve as quickly as they begin. ...Read more

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Dr. Daniel Saurborn
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


Dr. Katherine Kohari
38 doctors shared insights

Cholestasis Of Pregnancy (Definition)

A condition that can occur in pregnancy where the flow of bile, a digestive fluid produced by the liver, slows or stops. As a result, the bile enters the bloodstream and causes intense itching on the palms of the hands and the soles of the feet, plus ...Read more