Doctor insights on:
Is Hemophilia Dominant Or Recessive
Not always: Hemophilia a is a x-linked recessive gene. It means if a male has the defective gene, because they have 1 x and 1 y, they will have hemophilia. In order for a female to get it, she would have to get 1 copy from a carrier mother and a hemophiliac father. She would then have two copies of the bad chromosome and would have hemophilia. The chances of a female getting two copies is less than a male. ...Read more
Clotting problem: Hemophilia is a hereditary blood disorder in which the person is deficient in one of the body's clotting factors (factor viii for hemophilia a and factor ix for hemophilia b). Therefore the blood does not clot correctly after an injury. Depending on severity, patients with hemophilia bleed and bruise easily and for a longer time. Some may even bleed into their joints, muscles, or brain. ...Read moreSee 1 more doctor answer
Inheritance/genetics: Hemophilia is a disorder of clotting due to abnormal genes that are inherited from the mother by the son. Daughters are carriers but generally do not suffer from it. An affected man pass the gene to his daughters but can not pass it to the sone. Daughters pass the disease on to their sons. Rarely a new mutation, de novo, may occur to cause the disease that is then spread to the offspring. ...Read more
Very serious: Interferes with blood clotting, so subject can not easily stop bleeding when it occurs. Not just open bleeding, but into joints which when started will only stop when the pressure within the joint equals the blood pressure, so there is severe joint swelling followed by fibrosis (scarring) within the joint. Similarly uncontolled bleeding can occur into the GI tract and/or lungs. ...Read moreSee 1 more doctor answer
Hemophilia: The treatment of hemophilia depends on what type the patient has, how severely they are affected, and whether any surgical procedures are planned. Without knowing what type of hemophilia you are discussing i can't be more specific. A good source of information is the national hemophilia foundation at www.Hemophilia.Org. ...Read moreSee 1 more doctor answer
Gene for bleeding: The two common hemophilias are lack of factor viii (hemophilia a) and factor ix (hemophilia b) respectively. Of variable severity, these people are prone to bleed too easily especially from blunt trauma. Treatment consists of replacement of the missing factor and is a complicated business with specialists that are well-equipped to do this. Cure by gene therapy may soon be here for ix. Good luck. ...Read more
Bleeding disorder: Acquired hemophilia is when the body spontaneously makes autoantibodies (a signal that tells the immune response to respond to one of the body's normal components) for coagulation factor (these factors help with blood clotting) viii. This is usually in association with various autoimmune and chronic inflammatory diseases like lupus and rheumatoid arthritis. ...Read moreSee 1 more doctor answer
Hemo."A" is X-linked: Hemophilia "a" is a hereditary bleeding disorder where there is a deficiency in clotting factor viii (factor viii is needed for blood clotting). It is inherited on the x-chromosome (sex-linked). Men only have 1 "x", so if their "x" is mutated, they will have the disease. Women have 2 "x's", so they can have 1 mutated "x" and 1 normal "x", and be a carrier of the disease, with mild or no symptoms. ...Read moreSee 1 more doctor answer
Depends: There are two types of hemophilia (besides the a, b, c) - genetic (the most common and well-known) and acquired. Genetic is just that - it's from birth due to a genetic mutation. The acquired form develops later in life and is often caused by an immune reaction from an infection or substance (like a medication) that causes the immune system to attack certain parts of the hematologic system. ...Read more
Hemophilia panels: There are very specific panels to measure the overall clotting of the blood, and the exact measurement of the clotting factors involved with coagulation. In general hemophilia refers to hemophila a (a decrease in factor viii) or hemophilia b (factor (ix). ...Read moreSee 1 more doctor answer
It is more likely: Hemophilia mostly affects men. It is rare but not impossible for a female to have hemophilia. Hemophilia is a sex-linked recessive disorder: the trait is carried on the x chromosome which a female has two of and a male only has one. This means a female would have to inherit two copies of the hemophilia gene to have the disorder. A male only has to inherit one copy. ...Read moreSee 1 more doctor answer
Sex linked disorder: Hemophilia is inherited disorder of bleeding. Hemophilia a, deficiency of factor viii is commoner than hemophilia b due to deficiency of factor ix. Both are x-linked and affect boys/men only, with rare exceptions. Concentrated coagulation factors are given by intravenous injections to prevent and treat abnormal bleeding. ...Read more
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