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Doctor insights on: Is Having An Enlarged Spleen Is Always Associated With Other Diseases

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What is the connection between an enlarged spleen and anemia?

What is the connection between an enlarged spleen and anemia?

Hemolysis: Enlarged spleen is usually seen in anemia whenthe rbc is fragile. Many disorders can cause this. Fragile rbcs can then be broken down in the spleen (a process referred to as hemolysis). This causes different levels of anemia and an enlarged spleen. Often jaundice can be seen as well. ...Read more

Dr. Eric Weisman
182 doctors shared insights

Enlarged Spleen (Definition)

An enlarged spleen is a clinical finding in which the spleen is larger than in a normal, healthy person. This can occur with infections, diseases of ...Read more


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Is having an enlarged spleen is always associated with other diseases?

Is having an enlarged spleen is always associated with other diseases?

Most of the time: "hypersplenism" or enlarged spleen is a normal reaction by the spleen as it act as a filter for blood cells, bacteria, viruses; cirrhosis also gives rise to enlarged spleen due to portal congestion. Lymphoid cancers may occur in the spleen itself, causing enlargement. Another direct cause from spleen itself is an abscess due to infection or recent trauma. ...Read more

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Is it true that an enlarged spleen is always associated with other diseases?

No: Some folks have a biggish spleen for no reason. If disease is present, and if often is especially if the spleen is very large, a good history and physical exam with a CBC and chemical profile will detect it. At autopsy, i've found spleens up to 1000 gm for no obvious reason. ...Read more

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Can a enlarged spleen have anything to do with prostate disease?

Can a enlarged spleen have anything to do with prostate disease?

Not related: Spleen is related to the hemopoietic (blood) & lymphatic systems & not related to the prostate gland. ...Read more

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Crohn's disease and pancreatitis, enlarged spleen, what to do?

Crohn's disease and pancreatitis, enlarged spleen, what to do?

See your GI: You need to be seen by your gastroenterologist asap. There are several entities that could cause these findings. Pancreatitis is often a medication side effect from a crohn's disease medication. You could also have a stone in your bile ducts somewhere. You will likely need some imaging of your abdominal organs if you have not already had some. ...Read more

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Enlarged spleen caused by gallbladder disease, what to do?

Probably not GB: Gallbladder disease, most frequently cholecystitis, or inflammation of the gallbladder, does not cause enlarged spleen. Under very unusual circumstances, bacterial infection could cause some response or abscess in the spleen. More often, enlarged spleen or splenomegaly is a reflection of liver disorder, in which the gallbladder may also be affected. Check with your doctor. ...Read more

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Cat scratch disease & enlarged spleen, how are they related?

Cat scratch disease & enlarged spleen, how are they related?

Likely: About half of children have hepatomegaly or splenomegaly; the liver may be tender to palpation. Many of the patients with visceral involvement have no accompanying peripheral adenopathy. ...Read more

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My husband has elevated liver enzymes and an enlarged spleen. He was bitten by a tick about 4 yrs ago and was treated for Lyme disease with a zpack.?

My husband has elevated liver enzymes and an enlarged spleen. He was bitten by a tick about 4 yrs ago and was treated for Lyme disease with a zpack.?

Needs evaluation: Not all tick bites cause lyme, but if he got lyme a z-pak is not adequate treatment so he likely has chronic lyme. Ticks can also transmit babesia, bartonella, rickettsia & other serious infections. These might be causing his problems & his problems might be unrelated to the bite. He needs a thorough medical evaluation including a doc knowledgeable about lyme & co-infections. See www.Ilads.Org. ...Read more

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Have enlarged spleen&liver;low liver enzymes;hypocholesterolemia;pain in left shoulder front&back;extreme fatigue.Could liver disease cause this?

Have enlarged spleen&liver;low liver enzymes;hypocholesterolemia;pain in left shoulder front&back;extreme fatigue.Could liver disease cause this?

Serious: You should see your doctor asap. You are describing something serious, liver is mafunctioning secondary to something else. Pain in the shoulder is radiating there from something in the abdomen. Any weight loss, night sweats? You need an abdominal ct and blood tests. ...Read more

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