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Doctor insights on: Is Glioblastoma Hereditary

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Dr. Jefferson Chen
86 doctors shared insights

Glioblastoma (Definition)

Glioblastoma is the unnatural, uninhibited overgrowth of certain supportive cells in the brain (not the nerve cells themselves). Like other cancers, this can destroy good cells, often by pressure within the space of the skull. Unfortunately, it weaves its way between good brain cells and the limits of the growth usually cannot be known with certainty. That's why surgery alone ...Read more


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Are there any risk factors for glioblastoma? Mom died of GBM 8 yrs ago. Her Drs. said it was just vry bad luck & not hereditary, but I still worry.

Are there any risk factors for glioblastoma? Mom died of GBM 8 yrs ago. Her Drs. said it was just vry bad luck & not hereditary, but I still worry.

Do not worry: Your doctor is right and there is nothing to be gained by worrying. You may consult this site for more info: http://www.webmd.com/cancer/brain-cancer/glioblastoma-multiforme For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Mom died of glioblastoma after lifetime of good health. Can it be hereditary? Her surgeon and neuro-onc said it is very rare and happens at random.

Mom died of glioblastoma after lifetime of good health. Can it be hereditary? Her surgeon and neuro-onc said it is very rare and happens at random.

I agree: We are not aware why some folks get these nasty brain tumors, and why they transform as they do. Very rare to have familial genetics that cause this, and agree that there is no reason to worry, as this is most likely a matter of chance, and rather remote odds. ...Read more

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Where in the body does glioblastoma develop?

Where in the body does glioblastoma develop?

Brain: Glial tissue is mostly found in your brain. There are some gliomas or glioblastomas that arise in neural tissue outside the brain but the common ones are all in your brain. ...Read more

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What is the definition or description of: glioblastoma?

A bad brain tumor.: Glioblastoma is the unnatural, uninhibited overgrowth of certain supportive cells in the brain (not the nerve cells themselves). Like other cancers, this can destroy good cells, often by pressure within the space of the skull. Unfortunately, it weaves its way between good brain cells and the limits of the growth usually cannot be known with certainty. That's why surgery alone may not be successful. ...Read more

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Why are glioblastomas so common and is there anything a person can do to reduce the chance of getting one ?

Why are glioblastomas so common and is there anything a person can do to reduce the chance of getting one ?

Uncommon cancer: You have misunderstood something you read. Glioblastomas are relatively uncommon cancers, with about 12,000 new cases each year in the entire US. Not exactly rare, but that's 20 times and 15 times less common than breast cancer and prostate cancer, respectively. Most other cancers also are more common than glio. There is no known prevention against glioblastoma, so good thing it's pretty rare! ...Read more

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My dad has glioblastoma, what happens?

My dad has glioblastoma, what happens?

Treatment: These are typically treated aggressively surgery (if operable) followed by a combination of chemotherapy (temodar) and radiation, followed by more chemotherapy. Unfortunately these tumors have very bad prognoses. ...Read more

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What does the grade of a glioblastoma tumor indicate?

What does the grade of a glioblastoma tumor indicate?

Tumor grading: Grading of tumors is a way of "standardizing" the type of cancer, and thereby improving consistency of treatment between treating doctors/institutions. In gliomas as in other sites, a higher grade also implies a more aggressive tumor and potentially a poorer prognosis. However, some high grade tumors can be curable, whereas low grade tumors tend to linger but not respond to treatments. ...Read more

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How effective is radiosurgery for treating glioblastoma?

How effective is radiosurgery for treating glioblastoma?

Depends: This is difficult to answer. Glioblastoma is a very malignant tumor and very difficult to treat. The smaller the tumor the better the chances of "success " in treating the tumor with radiotherapy. Surgery also an option if again it is a small lesion. Unfortunately often times diagnosed at a late stage. ...Read more