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Doctor insights on: Is Glioblastoma Hereditary

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Dr. Jefferson Chen
89 doctors shared insights

Glioblastoma (Definition)

The unnatural, uninhibited overgrowth of certain supportive cells in the brain (not ...Read more


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Are there any risk factors for glioblastoma? Mom died of GBM 8 yrs ago. Her Drs. said it was just vry bad luck & not hereditary, but I still worry.

Are there any risk factors for glioblastoma? Mom died of GBM 8 yrs ago. Her Drs. said it was just vry bad luck & not hereditary, but I still worry.

Do not worry: Your doctor is right and there is nothing to be gained by worrying. You may consult this site for more info: http://www.webmd.com/cancer/brain-cancer/glioblastoma-multiforme For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Mom died of glioblastoma after lifetime of good health. Can it be hereditary? Her surgeon and neuro-onc said it is very rare and happens at random.

Mom died of glioblastoma after lifetime of good health. Can it be hereditary? Her surgeon and neuro-onc said it is very rare and happens at random.

I agree: We are not aware why some folks get these nasty brain tumors, and why they transform as they do. Very rare to have familial genetics that cause this, and agree that there is no reason to worry, as this is most likely a matter of chance, and rather remote odds. ...Read more

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Where in the body does glioblastoma develop?

Where in the body does glioblastoma develop?

The brain.: Glioblastoma multiforme is the term for a very aggressive tumor that arises in the brain. It is usually treated by a combination of surgery, radiation therapy and cheomtherapy. Unfortunately, these tumors are very aggressive, and although treatment can slow their growth, they invariably recur. They are most commonly found in middle aged adults. ...Read more

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What is the definition or description of: glioblastoma?

A bad brain tumor.: Glioblastoma is the unnatural, uninhibited overgrowth of certain supportive cells in the brain (not the nerve cells themselves). Like other cancers, this can destroy good cells, often by pressure within the space of the skull. Unfortunately, it weaves its way between good brain cells and the limits of the growth usually cannot be known with certainty. That's why surgery alone may not be successful. ...Read more

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Why are glioblastomas so common and is there anything a person can do to reduce the chance of getting one ?

Why are glioblastomas so common and is there anything a person can do to reduce the chance of getting one ?

Uncommon cancer: You have misunderstood something you read. Glioblastomas are relatively uncommon cancers, with about 12,000 new cases each year in the entire US. Not exactly rare, but that's 20 times and 15 times less common than breast cancer and prostate cancer, respectively. Most other cancers also are more common than glio. There is no known prevention against glioblastoma, so good thing it's pretty rare! ...Read more

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My dad has glioblastoma, what happens?

My dad has glioblastoma, what happens?

Treatment: These are typically treated aggressively surgery (if operable) followed by a combination of chemotherapy (temodar) and radiation, followed by more chemotherapy. Unfortunately these tumors have very bad prognoses. ...Read more

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What does the grade of a glioblastoma tumor indicate?

What does the grade of a glioblastoma tumor indicate?

Tumor grading: Grading of tumors is a way of "standardizing" the type of cancer, and thereby improving consistency of treatment between treating doctors/institutions. In gliomas as in other sites, a higher grade also implies a more aggressive tumor and potentially a poorer prognosis. However, some high grade tumors can be curable, whereas low grade tumors tend to linger but not respond to treatments. ...Read more

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How effective is radiosurgery for treating glioblastoma?

How effective is radiosurgery for treating glioblastoma?

Depends: This is difficult to answer. Glioblastoma is a very malignant tumor and very difficult to treat. The smaller the tumor the better the chances of "success " in treating the tumor with radiotherapy. Surgery also an option if again it is a small lesion. Unfortunately often times diagnosed at a late stage. ...Read more

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Glioblastoma multiforme, concerned?

Serious diagnosis: Glioblastoma multiforme is something that deserves aggressive attention. Although the overall prognosis for patients is poor, there are subsets of patients that have modest rates of being alive at 5 years with newer medications. Also, even newer treatments continue to be tested, including vaccines. Typically surgery is done first, followed by chemotherapy and radiation. ...Read more

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Glioblastoma multiforme, should I be concerned?

Yes: This is a serious diagnosis. I would recommend prompt treatment with surgery followed by chemotherapy and radiation. Although overall this diagnosis does not carry a good prognosis, some subsets of patients do better than others. Also, newer treatments continue to be investigated, including vaccine treatments. ...Read more

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Is it possible to resect a glioblastoma multiforme?

Is it possible to resect a glioblastoma multiforme?

Generally not: Glioblastoma is a high grade glial tumor. Glial tumors do not have distinct borders because glial cells have extensive cell projections and grow in a network ,rather than with discrete borders. Surgery can be performed to remove the bulk of tumor, but it is generally not possible to remove every tumor cell. Also, the location of the tumor often limits extent of surgery. ...Read more

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What is the difference between glioblastoma and glioma?

GBM is agressive: Glioblastoma is a malignant tumor of the brain. It often invasive and agressive form of brain tumor whereas glioma is often a benign primary brain tumor. Glioblastoma has the tedency to spread locally or to other part of the brain. Treatment of glioblastoma includes combination of surgery, radiatoin with or without chemotherapy. Gliomas usually do not spread and are treated by resection alone. ...Read more

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Is there any breakthrough treatment for glioblastoma anywhere?

Is there any breakthrough treatment for glioblastoma anywhere?

Not yet.: Please contact the american brain tumor association for current trials. If you mean "cure" the answer is unfortunately - not yet. Here the link http://www.Abta.Org/. ...Read more

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Is it possible to completely resect a glioblastoma multiforme?

Gbm: Yes but location and neurological compromise in most cases didn't allow that. ...Read more

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How successful is surgery in curing malignant glioblastoma surgery?

How successful is surgery in curing malignant glioblastoma surgery?

Not good alone: The standard management for glioblastoma includes surgery followed by radiation and chemotherapy. Radiation and chemotherapy following surgery is well established to improve the overall survival of patients compared to radiation alone. ...Read more

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When does a patient loose his speech after surgery of Glioblastoma?

When does a patient loose his speech after surgery of Glioblastoma?

A pt does not: necessarily lose speech after resection of glioblastoma. It depends on where the tumor is located in the brain. If not located in the speech center,speech will be preserved. ...Read more

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What are indications that glioblastoma cancer is in the final stages?

What are indications that glioblastoma cancer is in the final stages?

Losing performance: Gbm causes different signs depending on location, and growth on MRI signal progression. But decreasing ability to do daily activity, get out of bed, dress, walk, control bowel and bladder function are signs that time is short. Salvage treatment is used in able patients, and those willing to volunteer, but assess what benefit your patient gets and at what price. ...Read more

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