Top
10
Doctor insights on: Is Gender A Factor In Thalassemia

Share
1

1
Do environmental factors play a role in the progression of beta-thalassemia?

Do environmental factors play a role in the progression of beta-thalassemia?

No, but. . .: Environmental factors generally do not play a role in beta thalassemia. However, a patient can be worsened by conditions that typically worsen anemia, such as dietary iron deficiency, other nutrient deficiencies (such as folate (folic acid) or vitamin b12), lead poisoning, or infections with viruses that can cause anemia (such as parvovirus b19). Vacationing at high altitudes may cause symptoms of low oxygen. ...Read more

See 1 more doctor answer
Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

Thalassemia is sever anemia,it ...Read more


2

2
If a girl with G6PD want to marry someone with with thalasemia what are the risk factors of having kids? Is it bad?

If a girl with G6PD want to marry someone with with thalasemia what are the risk factors of having kids? Is it bad?

How severe?: Thal minor and mild G6PD deficiency are both very minor and very common clinical problems. If you're in love, then I'm happy for you both. ...Read more

3

3
My brother has Thalasemia, little liver sweeling.Recently 17mm gallstones has diagnosed.What will be the treatment and risk factors for him ?

My brother has Thalasemia, little liver sweeling.Recently 17mm gallstones has diagnosed.What will be the treatment and risk factors for him ?

Gallstone ? disease: Stones in the gallbladder (gb) seldom cause symptoms unless they migrate into the neck of the gb (& block exit of bile) or into the common bile duct. Symptomless gallstones may be diagnosed by chance by imaging or during investigation for some other condition. Only 10% become symptomatic within 5 years of detection. Ultrasound, ct scan, mrcp finds stones; cck-hida scan can tell if gb is diseased. ...Read more

See 2 more doctor answers
4

4
What is thalassemia?

What is thalassemia?

Thalassemia: Thalassemia is a deficiency in the production of one of the globin chains (alpha or beta) that make up hemoglobin. Normally synthesis of these is balanced. When imbalanced, one globin accumulates relative to the other forming inclusions that are damaging to the red cells that contain them. There are many thal variants that manifest a wide severity of symptoms from none to transfusion dependence. ...Read more

See 2 more doctor answers
5

5
What is thalassemia?

What is thalassemia?

Familial blood trait: Thalassemia runs in families. It is caused by variations (mutations) in DNA, which is then passed on to future generations. There are many variations in the DNA (genes) that code for hemoglobin molecules inside red blood cells. Some of these variations cause the hemoglobin production to be very slow, so blood cells stay too small because they can't form enough hemoglobin to grow to normal size. ...Read more

6

6
How common is thalassemia?

Millions of carriers: Thalassemia is one of the most common gene mutations in the world. Overall, an estimated 20-25 million people are carriers (1/300) (about 1/1000 in low-risk peoples, and about 1/30 in high-risk peoples). Low risk: japanese, korean, n. European caucasians, native canadians, native americans. High risk: mediterranean, middle eastern, south asian, south-east asian (western pacific rim), caribbean. ...Read more

See 1 more doctor answer
7

7
What exactly is thalassemia?

See below: Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form of hemoglobin, the protein in red blood cells that carries oxygen. The disorder results in excessive destruction of red blood cells, which leads to anemia. ...Read more

8

8
How is thalassemia diagnosed?

How is thalassemia diagnosed?

Blood tests: Thalassemia is diagnosed by blood tests: routine blood counts, hemoglobin electrophoresis to find out the types of hemoglobin one has in one's blood, and dna analysis to try to see if certain mutations are present. ...Read more

See 1 more doctor answer
9

9
How is thalassemia inherited?

How is thalassemia inherited?

From Mom and/or Dad: Alpha thalassemia is caused by a mutation in one or more of the 4 genes that code for (holds the dna for) Alpha globulin, which is needed to make hemoglobin for new red blood cells. Beta thalassemia is caused by a mutation in one or both of the 2 beta globulin genes. Mom and/or dad can carry the mutations. A child can inherit a mutation from mom, from dad, or from both mom and dad. ...Read more

See 1 more doctor answer