Doctor insights on:
Is Excess Dose Of Combiflame Become Death
I understand renal impairment can cause a build up of haloperidol & hydromorphone in the body. Is this risk reduced by the use of high dose diuretics?
No: renal failure may cause side effects and diuretics will worsen it . ...Read more
How much nicotine is potentially delivered per cigarette and what is the daily dosage below which withdrawal symptoms develop?
No answer.: Nicotine delivery per cigarette varies with brand, filter, length of the inhaled draw, and how close to the end it is smoked. There is as much a 10 fold delivery difference with these factors, on average. It is very difficult to compare oral (nicorettes) or nicotine patches, because nicotine is inhaled. Withdrawal sx can begin with a 20% reduction in nicotine dosage. ...Read moreSee 1 more doctor answer
How (neuro) toxic and eventually life threatening is excess amount of tyrosine in the absence or very low presence of vitamin c?
Confusion here: Tyrosine is an amino acid, helpful in certain brain and mood disorders when taken as a supplement. Vitamin c is a water soluble vitamin, rarely measured accurately, considered safe to 5000 mg/ day supplementation by a famous physician who remained healthy and researching until his late 90's. A low vitamin c level can be corrected immediately. Your problems sound vascular/ hormonal, not toxic. ...Read more
Lorazepam dose: Maximum dose/day for Lorazepam is 10mg/day but this is rarely needed. This pill is available in 2mg. Usually 2-6 mg/day in divided doses is rx. In us you can get a dui even if under the influence of a medication prescribed by a physician. Your treating professional should prescribe the lowest dose/day that addresses your symptoms with the lowest possible side effects. Talk to your dr 1st. ...Read more
Is one normal dose of tylenol (acetaminophen) (say 500mg) more or less damaging to the liver than 2-3 alcoholic beverages?
Not sure.: All of the NSAID's carry approximately the same toxicity when given at equivalent dose. The major concern is renal and not liver toxicity. ...Read more
Is too Lasix (furosemide) dangerous in nephrotic syndrome? Can doses of 120 mg qd - bid to produce weight loss of 1-2 lbs./day result in further kidney damage?
Loop diuretics about: inhibiting tubular absorption, not glomerular filtration: the glomerular pathology of nephrotic syndrome. Thus no! If anything, Lasix, (furosemide) & other loop diuretics, up to a point, may be slightly protective by inhibiting concentration, diluting cleared proteins within the distal tubules & collecting ducts, etc. Nephrotic syndrome promotes edema due to loss of albumen: responsible for preventing edema. ...Read more
What is the effect of taking 5mg diazepam with a beer, 2 units. Does alcohol increase the sedative effect ?
Because of the timed-release feature of Lunesta, (eszopiclone) is its effectiveness compromised if a tablet is cut in half and taken?
Which ritalin (methylphenidate) ir doses and concerta doses are considered risky for causing psychosis ? So beginning which dose psychosis risk is high ?
Are liver damage, caused by taking very high doses of nicotinic acid for years, irreversible?if you block the intake, will the liver return as before?
Liver Damage: Possibly. Get evaluated by a liver specialist (hepatologist) GI doctor. ...Read more
What causes accumulation/formulation of body fuids (in severe cases 750 ml) besides the walls of heart?
Many: Many things can do this: lack of protein in bloodstream due to nutrition issues or kidney dysfunction; unrecognized sleep apnea; venous insufficiency of the legs along with excessive sodium ingestion to name a few. Also, certain medicstions may provoke fluid retention, Actos (pioglitazone) and nonsteroidals (eg naproxen) to name a few. ...Read more
Fairly significant!: Age appeares to be the predominant factor influencing the risk of developing isoniazid-related hepatitis (increasing age is associated with an increasing risk). Drinking alcohol, especially on a daily basis, enhances the risk of hepatitis among those taking isoniazid.Weighing the benefits of Isoniazid in preventing tuberculosis against the risk of its causing hepatitis nec. F/u with your doctor. ...Read more
Is it true that opioids in higher doses have antiemetic effects vs lower doses because it depresses the vomiting center?
yes: High doses of some opioids may decrease n/v by interacting with receptors in the vomiting center, rather than the ctz (chemoreceptor trigger zone ).The relationship between opioids use and n/v is complex. The vomiting center in the medulla oblongata, receives input from 4 areas; chemoreceptor trigger zone gi tract vestibular apparatus -temporal lobe cerebral cortex. ...Read more