Doctor insights on:
Is Esophageal Cancer Slow Growing
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Slow or Fast: It can be slow or fast, but generally its a slow process. Esophageal cancer tends to be circumferential, like a donut. As it grows, the hole or lumen becomes smaller, and can make it diffiult for food, then liquids to pass through. The diamter of your esophagus can get as narrow as 6mm (18french) before one gets symptoms. ...Read more
Depends on the stage: There are 4 stages of esophageal cancer. Stage i-iii can be considered operable if the patient is of good physical condition. Tumor growing through the esophagus and into surrounding lymph nodes (regional) would be stage iii and still potentially operable. Tumor involving unresectable structures like the heart or bone, or that have metastastasized to distant organs (like brain) are inoperable. ...Read more
Had Total gast for esophageal cancer at gej. 3 months later trouble swallowing. R1 resection. Could a tumour grow this quickly or more likely I need dilation?
Could be tumor: Treatment is usually RT/Chemo followed by resection lower 1/3 esoph. Frequently repeat trans esophageal ultrasound shows complete absence of any residual mucosal tumor. At times residual tumor cells only present in submucosa of remaining esoph and this is the most common cause of recurrence. This exam must be repeated along with PET/CAT ...Read more
Depends on stage: There are 4 stages of esophageal cancer (with a and b subtypes for some). For stage I and iia, the upfront therapy is surgery or esophagectomy. For stage iib or iii, treatment is chemoradiation followed by surgery, or definitive chemoradiation. For stage iv, the treatment is chemotherapy, + /- radiation. ...Read more
Depends on the type:
Squamous cell carcinoma of the esophagus for the most part is casued by smoking, consuming alcohol, nitrosamines, such as pickled foods and smoked meats.
Adenocarcinoma is casued by acid reflux, which can lead to injury of the lining of the esophagus, causing barrett's metaplasia. Barrett's can lead to low grade, then high grade dysplasia, and finally esophageal adenocarcinoma. ...Read more
Two major types: The most common in this country is adenocarcinoma. The second most common is squamous cell carcinoma. There are other very rare types such as melanoma, lymphoma and small cell. Also, esophageal cancer is categorized by location, i.e. Bottom third, middle third and upper third of the esophagus. The majority in this country are in the lower third. ...Read more
IV: There are 4 stages for esophageal cancer, with a and b substages. We use roman numerals. For stages I - iia, the treatment is the physically fit patient is surgery or esophagectomy. For stages iib and III the treatment is chemotherapy and radiotherapy, followed by surgery, or in patients who do not want surgery, chemoradiotherapy alone. For stage IV treatment is chemotherapy +/- radiation. ...Read more
Coughing in esophageal cancer is usually caused by airway (aka bronchus or wind pipe) irritation, most commonly by:
1. Aspiration (saliva and/or food going into the airway) due to obstruction of the esophagus by tumor
2. A large tumor pushing on or growing into the airway. ...Read more
On what stage it's found at. Earlier stages that don't show any spread of the cancer can be cured with surgery. Once the cancer has spread, the prognosis worsens. When it has spread to other organs, the chance for cure becomes very low with chemoradiation alone.
5 year survival rates for those without spread is about 37%. If it has spread to the lymph nodes, 18%. To other organ, 3%. ...Read more
About 40%: Esophageal Ca survival depends on type of tumor and extent of disease when defined. Transesophageal ultra sound is helpful in defining extent of tumor invasion into the wall as well as nodes. PET/CAT looks for distant spread. Pretreatment with RT and chemo followed by surgery in Stage I disease gives about 40-50% five year survival. ...Read more
Depends on type: For adenocarcinoma, the risk factors are mainly acid reflux, leading to barrett's metaplasia, and being male. The risk factors for squamous cell carcinoma include smoking, alcohol, radiation exposure, other head and neck cancers, caustic ingestion, a condition called achalasia, eating foods with nitrates, and conditions called chaga's disease and tylosis. ...Read more