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Doctor insights on: Is Erythroblastosis Fetalis Is An Example Of Autoimmunity Or Isoimmunity

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Is erythroblastosis fetalis is an example of autoimmunity or isoimmunity?

Is erythroblastosis fetalis is an example of autoimmunity or isoimmunity?

Alloimmunity: Autoimmunity is an immune response to one's own proteins while the example of Erythroblastosis fetalis is an immune response of mom's antibodies to a foreign antigen, this case from the fetus. ...Read more

Autoimmunity (Definition)

Autoimmunity is failure of an organism in recognizing its own constituent parts as self, which allows an immune response against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Autoimmunity is often caused by a lack of germ development of a target body and as such the immune response acts against its ...Read more


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Can you please define erythroblastosis fetalis?

Can you please define erythroblastosis fetalis?

Hemolytic disease: Erythroblastosis fetalis is also called hemolytic disease. Babies develop this condition before they are born. Erythroblastosis fetalis occurs when you and your baby have different blood types. When your baby's blood mixes with your blood during pregnancy, your immune system reacts by making antibodies against it. ...Read more

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Why does erythroblastosis fetalis only occur due to Rh factors?

Why does erythroblastosis fetalis only occur due to Rh factors?

Misconception: It is a misconception that erythroblastosis fetalis can only occur in rh negative moms who carry a Rh pos baby. Mom can develop antibodies against a variety of other components of the human blood system that can cause erythroblastosis in the baby - fortunately these conditions are rare. ...Read more

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My baby died due to erythroblastosis fetalis is there still a chance for me to have another pregnacy and have a normal baby?

My baby died due to erythroblastosis fetalis  is there still a chance for me to have another pregnacy and have a normal baby?

Several chances: The father may have only a 50/50 chance of transmitting the gene of the protein that your blood reacts to and attacks causing anemia. Then, if it is present and the baby has blood that your blood reacts to, transfusion can be done in utero (it is risky) http://www.merckmanuals.com/professional/gynecology_and_obstetrics/abnormalities_of_pregnancy/erythroblastosis_fetalis.html ...Read more

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If an rh-positive baby is suffering from erythroblastosis fetalis. An exchange transfusion is performed, why?

If an rh-positive baby is suffering from erythroblastosis fetalis. An exchange transfusion is performed, why?

Increase RBC mass: Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) ...Read more

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An rh-positive baby is suffering from erythroblastosis fetalis. Why would an exchange transfusion be performed?

An rh-positive baby is suffering from erythroblastosis fetalis. Why would an exchange transfusion be performed?

Increase RBC mass: Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) ...Read more

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Can you tell me about fetus with Rh negative blood, will the fetus be in danger of developing erythroblastosis?

Can you tell me about fetus with Rh negative blood, will the fetus be in danger of developing erythroblastosis?

Actually no: A positive baby in a negative mother is at risk, but usually only if Mom wasn't properly treated previously. Today these problems are rare in people who are compliant with evidence-based medicine. ...Read more

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What is autoimmunity's role in type 1 diabetes?

What is autoimmunity's role in type 1 diabetes?

It is an autoimmune: Type i diabetes begins as a body's attack pancreas specifically the islet cells. Eventually this leads to an impairment in the production of insulin, and a dysregulation of glucose homeostasis. It almost always needs to be treated with Insulin and a skilled physician (usually an endocrinologist). ...Read more

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What's the difference between immunodeficiency and autoimmunity?

What's the difference between immunodeficiency and autoimmunity?

Function and target: The immune system should react against substances that harm us, and should tolerate substances that do not harm us. In immunodeficiency, there is a weakness on the immune response. Infectious occur frequently and more severe. In autoimmunity, there is malfunction on the immune response, targetting our own tissues, such as our joints in rheumatoid arthritis. Both processes may occur together. ...Read more

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What is the difference between autoimmunity and polymyalgia rheumatica?

What is the difference between autoimmunity and polymyalgia rheumatica?

See below: Pmr is an auto immune disease. In auto immune diseases certain types of white blood cells attack your own tissues and cause cell or tissue destruction. Lupus and rheumatoid arthritis are two common examples. In these cases the immune system must be modulated, sometimes with powerful medications. ...Read more

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