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Doctor insights on: Is Enbrel Or Humira A Narcotic Drug

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Narcotic (Definition)

A natural or synthetic alkaloid compound that has morphine-like qualities. Other examples are codeine, heroin, Meperidine (demerol). They are classified based on their intrinsic activity & where they interact in the central nervous system. They are involved in pain transmission ...Read more


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Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more

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Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more

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Are there other alternatives to enbrel (etanercept) and humira?

Are there other alternatives to enbrel (etanercept) and humira?

Yes: It depends on the disease being treated. For psoriasis (my field is dermatology), there is infliximab (remicade), ustekinemab (stelara), alefacept (amevive) - not used much now and golimumab (simponi) - not used much either. ...Read more

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I was on humira and felt terrible, is enbrel (etanercept) any better?

It's different: Different people react differently to different medications. It is possible that you will have the same trouble with Enbrel (etanercept) but it's also possible that you will have no trouble with enbrel (etanercept). The only way to know for certain is to try it. ...Read more

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What is the difference in mechanism or humira and enbrel (etanercept)?

None: There both basically work by the same mechanism which is inhibition of tnp. ...Read more

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What's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? Do all patients develop immunity?

See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate. However; not all patients are candidate to be on methotrexate. Some patients never have a problem and some do. It is hard to comment on the average amount of time because it is an individual phenomena. ...Read more

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Is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

No great...: No great differences. Enbrel (etanercept) is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! both should be tried only after Methotrexate therapy has failed! ...Read more

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On actemra (tocilizumab) IV(dose increase in dec)and methotrexate for 5 mon now but still having bad flare ups. Tried humira,enbrel,etc. since diagnosis in Dec 2013?

Your question is?: Your have not asked a question. This issue needs to be discussed with your rheumatologist. No one can give you specific advice over the internet without a complete history and exam. ...Read more

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Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte.Do u think psorias will clear?Y did humira (adalimumab) stop working?Stress overpower it?

Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this. ...Read more

Dr. Robert Lowe
121 doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more


Dr. Robert Lowe
140 doctors shared insights

Enbrel (Definition)

Enbrel is an immune system suppressor which is a kind of ...Read more