Doctor insights on:
Is Enbrel Or Humira A Narcotic Drug
Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?
Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more
A natural or synthetic alkaloid compound that has morphine-like qualities. Other examples are codeine, heroin, Meperidine (demerol). They are classified based on their intrinsic activity & where they interact in the central nervous system. They are involved in pain transmission ...Read more
Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?
One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more
Switching meds: The current recommendation is to try a medication with a different mechanism of action. That being said, before there were so many options, switching between Enbrel and Humira was quite common. Sometimes it helps, just as sometimes one pill in a class of drugs works better than another. ...Read more
Same!: They work similarly!Get a more detailed answer ›
What's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? Do all patients develop immunity?
See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate. However,; not all patients are candidate to be on methotrexate. Some patients never have a problem and some do. It is hard to comment on the average amount of time because it is an individual phenomenon. ...Read more
On actemra (tocilizumab) IV(dose increase in dec)and methotrexate for 5 mon now but still having bad flare-ups. Tried humira, enbrel,etc. since diagnosis in Dec 2013?
Your question is?: Your have not asked a question. This issue needs to be discussed with your rheumatologist. No one can give you specific advice over the internet without a complete history and exam. ...Read more
Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte. Do u think psorias will clear? Y did humira (adalimumab) stop working? Stress overpower it?
Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this. ...Read more
See list: In the usa, the available tnf inhibitors are Adalimumab (humira), Etanercept (enbrel), certolizumab pegol (cimzia), golimumab (simponi), and Infliximab (remicade). ...Read more
See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read more
Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade (infliximab) Which is better? I'm confused snd do know what to do!
TNF Inhibitors: All the medications offered to your child work in similar ways the difference is how the meds are given. Humira (adalimumab) is an injection that can be done at home every two weeks, while remicaide is an IV medication that must be done in an infusion unit or hospital. These medication have similar side effects and benefits. My advice is try the medication that is least disruptive to your lifestyle. ...Read more
Dx:ra. Enbrel (etanercept) not effective after 6 mo. Humira 2x mo prescribed. Liver can not tolerate mtx. What medication can replace mtx to make humira work best?
What is it like to have any experience with blood monitoring for anti tnf therapy (humira/enbrel) whilst traveling for multi stop flights abroad?
See details: People who are stable on TNF biologics do not require blood test monitoring more than once every 3 months. Those in my practice who have been stable for years only have monitoring every 6 months. ...Read more
My RA doc wants me to take Enbrel/ Humira (adalimumab). Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?
Talk to RA doctor: These are issues which need be discussed with your RA doctor. In medicine, most decisions made are based on risk/benefit ratio and without knowing that, it is impossible to provide you with an answer in this type of interaction. ...Read more
RA + psoriasis. MTX allergy. Enbrel (etanercept) non-effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?
RA + psoriasis: There are a number of newer medications that could help you. Xeljanz works by disrupting cytokine and growth factor signaling pathways. A trial of the medication is useful to see whether it helps you. Other medications that might help include Remicade (infliximab) and Apremilast ...Read more
Would a doctor ever prescribe an anti-TNF such as Enbrel (etanercept) or Humira for mechanical non-malignant back pain or a lumbar strain?
Although: Evidence may show some benefit, cost make it impractical. ...Read more
Is there another way to treat my psoriasis from psoriatic arthritis? So far have tried uv therapy, low dose radiation treatment, methotrexate, humira, enbrel, halabetasol ointment, coal tar, hylatopic, and any other cream my dermatologist could think of.
Wow: You have been through a lot. I would try the mayo clinic in mn. ...Read more
Besides enbrel (etanercept) and humeria what are other biolgics or infusions can a. 7 year old take for juvenile idiopathic arthrits?
See list: Remicade, Rituxan, Actemra, Simponi (golimumab), (golimumab) Cimzia, Orencia. Remicade, Simponi (golimumab) and Cimzia are TNF agents. ...Read more
Dear doctors, as a person with ankylosing spondylitis, could you tell about the price of tnf-inhibitors, such as etanercept, infliximab, adalimumab?
Very few OTC drugs!: There are few otc weight loss drugs that work for any duration without tolerance, and rapid weight gain ocurring with cessation. Good nutritional support is your best bet, combined with exercise. That having been said, ephedrine, guarance, phenylpropanolamine, caffeine, provided you do not od on these, can be taken with enbrel (etanercept). ...Read more
Child has injection site reactions on enbrel and vomits after getting shot even with Zofran (ondansetron) what would be a good alternative drug for JRA?
Other biologic.: The details of your child's history and past treatments are unknown, of course, but one could consider an alternative biologic. Each one is designed differently than others. I urge setting up a follow up with your child's pediatric rheumatologist to discuss further. Good luck and hope they feel better. ...Read more
Why does it take so long for certain insurances to approve drugs like Enbrel (etanercept)? Do they enjoy making patients suffer while we're at their mercy?
See details: You have asked a very important question that continually frustrates patients and doctors. My cynical explanation is that it is always about money. ...Read more
Would any rheumatologist ever suggest enbrel (etanercept) to a patient who doesn't have rheumatoid arthritis, anspon, juvenile or psoriatic arthritis? Serious drug
Yes: Enbrel (etanercept) does have value in other disorders so I have recommended its use in diseases not on your list. ...Read more
Is there a drug that's less expensive and can be used as an alternative to humira (adalimumab) for rheumatoid arthritis?
YES: There are multiple drugs for arthritis cheaper than humira. Pills like methotrexate, sulfasalaxine, Plaquenil (hydroxychloroquine) and Leflunomide can be used alone or in combination. There is also an injectable form of Methotrexate that can sometimes be more effective. Prednisone can also be taken. Non-steroidal anti-inflammatories can be used. Depending on your insurance, another biologic may be cheaper than humira. ...Read more
Drug interaction of humira (adalimumab) with niacin
Can taking niacin affect the effectiveness of humira (adalimumab)?
No: Though interactions were reported in patients taking these two agents, Humira (adalimumab) and niacin, the patients were taking multiple other medications. It was not shown to be an interaction between the Niacin and humira (adalimumab). To test it individually, the Niacin could simply be stopped for a month assuming the Niacin was being used to treat hyperlipidemia. Ask your doctor if it is safe to hold the niacin. ...Read more
Why does it sting so much when I take humira (adalimumab)? It's not the needle, it's the drug itself when I am injecting it
Humira (adalimumab) hurts: Humira (adalimumab) is a great drug in terms of its effectiveness for arthritis, uveitis, inflammatory bowel disease and other autoimmune but it hurts everyone who gets this medication. I have spoken to Humira (adalimumab) drug reps about this since I prescribe it to kids. There is something in the formulation that causes the stinging. Try warming med to body temp under your arm for 10 min before injecting. It helps some. ...Read more
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