Doctor insights on:
Is Donating Bone Marrow Painful
No: A bone marrow or peripheral blood (pb) stem cell transplant (sct) is not painful. There are various "induction" treatments that depend on the type of cancer or disease to "condition" or get rid of the cancer (& normal) cells. A sct then "rescues" the bone marrow by returning self (autologous sct) cells or cells from another (allogeneic sct). The sct itself is similar to a blood infusion. ...Read moreSee 2 more doctor answers
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
Variable: The actual transplant which is the reinfusion of the bone marrow or stem cells is not painful. However there can be side effects to the radiation and/or chemotherapy used to treat the patient before the stem cell infusion. Depending on how the transplant is done those treatments can cause some unpleasant side effects including nausea, vomiting, abdominal pain and mouth sores among other things. ...Read more
Under gen anesthesia: Donating bone marrow for transplantation entails a procedure called bone marrow harvesting. The donor is placed under general anesthesia and turned over to lie on his/her belly to expose the hip bones on the back. Multiple aspirations of bone marrow are collected (average about 1 liter) at adjacent sites on the hip bone on both sides until a particular number of cells are reached. ...Read more
See below: A bone marrow transplant is the replacement of blood forming elements. The transplant is actually done with peripheral blood stem cells, and infused like a blood transfusion. The need for a transplant is because the treatment for certain diseases requires high doses of chemotherapy or radiation therapy that will destroy one's marrow completely. This then requires replacement with another's marrow. ...Read more
The procedure is not: The actual BM transplant (infusion of cells) is not at all painful. There may be some reactions during infusion such as chills, rigors, fever and others but pain is not common. However, there may be significant discomfort from the effects of chemotherapy and/or radiation that may result in severe mucositis (irritation of the lining of mouth, upper airway and swallowing tube) lasting few weeks. ...Read more
Home of blood cells: The cells in your blood are born and reach maturity in the bone marrow. This is the very protected space in the middle of your large bones like your arms, legs, hips and back. Once the cells are mature, they are released into the blood stream where they travel throughout the body preventing infection (granulocytes, lymphocytes), supply oxygen (red cells) and prevent bleeding (platelets). ...Read moreSee 1 more doctor answer
The patient is donor: In case of myeloma certain lymphomas in general patients receive chemotherapy , achieve a response and then have stem cells mobilized from their marrow- frozen- patient goes through high doses of chemo to clear the marrow or kill as many tumor cells as possible and then reinfuse cells back. The idea is that high doses of chemotherapy can cause prolong remission or cure ...Read moreSee 2 more doctor answers
Like a transfusion: Bone marrow transplantation is a long drawn out process. The marrow (or blood stem cells) is actually just infused IV like a blood transfusion. That's the easy part. Often high dose chemotherapy or radiation is given ahead of time. If the marrow comes from someone else then long courses of immune suppressive treatments are needed to control an inflammatory reaction called graft vs host disease. ...Read more
Bone marrow : The actual infusion of the cells does not hurt. The side effects of the chemotherapy and/or radiation therapy that are part of the preparative regimen of the transplant can be unpleasant. This can include nausea, vomiting, diarrhea, mouth sores, infections. ...Read moreSee 1 more doctor answer
Let me explain: 1-we have to have a donor who donate that, we do collect the bone marrow from him we call this step (harvesting) 2-we have to transplant this marrow to the recipient (patient receiving the bone marrow). 3-both involve special collecting method and method of delivery , done under anesthesia use some big needles to harvest. Some time require small surgery under anesthesia. ...Read moreSee 2 more doctor answers
Can be normal.: Up to 5% is normal as long as they are not "monoclonal" meaning derived from a cell. If monoclonal then a bone cancer called myeloma needs to be ruled out. If no bone disease, anemia, high calcium or kidney disease answer is MGUS, a pre-cancerous condition with low risk of progression (less than 1% per year). ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
- Talk to a doctor live online for free
- Is donating bone marrow bad for you?
- What are the risks of donating bone marrow?
- Is a bone marrow biopsy painful?
- Ask a doctor a question free online
- Is bone marrow test painful?
- How much bone marrow can you donate?
- How much does donating bone marrow pay?
- How often can you donate bone marrow?
- Talk to a hematologist online for free