Doctor insights on:
Is Dcis Caused By Stress
Stress affects most people in some way. Acute (sudden, short-term) stress leads to rapid changes throughout the body. Almost all body systems (the heart and blood vessels, immune system, lungs, digestive system, sensory organs, and brain) gear up to meet perceived danger. These stress responses could prove beneficial in a critical, life-or-death situation. Over time, however, repeated stressful situations put a strain on the body that may contribute to physical and psychological problems. Chronic (long-term) stress can have real health consequences and should be addressed like any other health concern. Fortunately, research is showing that lifestyle changes and stress-reduction techniques can help people learn ...Read more
Unknown: It is very difficult if not impossible to attribute one factor alone as a cause of breast cancer. A recent study looked at stress levels in breast cancer patients and found the stress scores higher in those with more aggressive cancers, but it's hard to know whether the stress caused the aggressive form or if the aggressive cancer caused more stress. Regardless, stress, obviously, is never good. ...Read moreSee 2 more doctor answers
Should tamoxifen be stopped if it caused endometrium thickening? Taking it for dcis, will it lead to endometrium cancer if continued?
Probably not: In a female in their 20's the discovery of dcis is unusual and raises possibility of the need for prevention of other breast disease with tamoxifen furthermore endometrium cancer is very unusual in a women on tamoxifen of this age and particularly if she still has periods most doctors if concerned by thickening will do a biopsy and resolve the concern. ...Read more
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
Genetic mutations: This is mostly a random event. There's a natural instability in the human genome even if you are never exposed to anything that's obviously a mutagen. The other factors that place you at risk for breast cancer (nulliparity, brca1 / brca2 mutations, etc.) are risk factors here, but no woman (and actually no man either) is immune. ...Read more
Should tamoxifen be stopped if it caused endometrium thickening? Taking it for dcis, will it lead to endome cancer if continued? Asking about mom 54yr
It depends...: Endometrial thickening does not equal cancer. Tamoxifen can be continued but the endometrium should be investigates with consultation with a gynecologist. Tamoxifen should be discontinued only if the endometrial biopsy shows any atpia. But the best guidance should come from a gynecologist. ...Read moreSee 1 more doctor answer
In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read moreSee 1 more doctor answer
Throbbing headache at night, tired feeling, trouble sleeping, blurry vision at times, high bp, no interest in anythg. Diagnosed with DCIS in 2012.
Depression, Anxiety: I understand your distress. “Throbbing headache, tired feeling, blurry vision at times” are likely due to High B.P. which can increase further with stress.. “trouble sleeping, no interest in anything” are likely due to anxiety and depression. See your Physician for High B.P and DCIS. See Psychiatrist for Therapy for stresses of relationships, separation, loneliness, insomnia and medical illness. ...Read more
Yes: Dcis may be classified into different types based upon the pattern of growth when viewed under a microscope. These include comedo, papillary, cribiform, and solid. The comedo form tends to have the highest potential for becoming invasive if left untreated. Dcis may also be classified by how rapidly the cancer cells are dividing; this is referred to as the grade of the cancer. ...Read moreSee 1 more doctor answer
Unknown: If we knew the answer to this question, women with dcis would not all need surgery! about 50% of dcis (ductal carcinoma in situ), if left untreated, will go on to become invasive cancer. Certain genes in the dcis cells get "turned on", making them invasive, but we don't know what makes this switch happen. ...Read moreSee 1 more doctor answer
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