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Doctor insights on: Is Dcis Breast Cancer Genetic

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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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Dr. Barry Rosen
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Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is breast cancer inherited?

Is breast cancer inherited?

Sometimes.: It is estimated that approximately 10-15% of all breast cancers in the US are of the hereditary type. These genes can be inherited from either your father or your mother. If a woman inherits this gene, they have a 50-75% chance of developing breast cancer in their lifetime. These cancers tend to occur at any earlier age and may occur in both breasts. ...Read more

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Is breast cancer hereditary?

Is breast cancer hereditary?

Sometimes.: It is estimated that 10-15% of all breast cancer cases in the us occur due to hereditary factors. This risk may be identified by doing a simple blood test to check for brca mutations. We generally advise testing family members with known breast cancers first before checking unaffected family. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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Is breast cancer preventable?

Is breast cancer preventable?

Partly: You can lower the odds of developing breast cancer by limiting alcohol intake to no more than a drink or 2 per day (and mostly red wine), exercising regularly, and keeping your weight under control. ...Read more

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Is ovarian cancer genetic?

Is ovarian cancer genetic?

Sometimes: Certain genotypes such as the brca mutations have a higher incidence of ovarian cancer. ...Read more

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Is pancreatic cancer genetic?

Is pancreatic cancer genetic?

A minority is.: Pancreatic adenocarcinoma, arising from ducts/epithelial tissue, is mainly "sporadic", but can run in families. Pancreatic cancer has also been related to brca mutation, fammm syndrome, and some other inherited conditions. The familial pancreatic cancer registry is at johns hopkins. A minority of neuroendocrine tumors of the pancreas are associated with multiple endocrine neoplasia (men) syndromes. ...Read more

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Is breast cancer autosomal dominant?

Is breast cancer autosomal dominant?

Well...: ...most breast cancers (80-90%) are not related to inherited traits so in those cases your question does not apply. However, the majority of high risk genes that cause breast and other cancers (like BRCA) are indeed transmitted as autosomal dominant traits. ...Read more

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What is hereditary breast cancer risk?

What is hereditary breast cancer risk?

Certain genetic: Risks, brca 1 & 2, are known, other are not, but familial clusters (mother, aunt sister) point to risk but the actual cause and function of the genetics are mysterious. We humans have a hard time with "risk". Some with no risk delvelop a cancer; others with high risk do not. The statistical facts work epidemiologicallyfor populations, but are not informative for an individual. They do cause worr. ...Read more

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What is metastatic breast cancer?

What is metastatic breast cancer?

Spread : This means that the cancer has spread to other areas outside of the breast. This is known as stage 4. With the use of modern chemotherapy, this disease can be controlled. I recommend you meet with your medical oncologist to determine options available for treatment. ...Read more

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What is the hereditary breast cancer gene?

What is the hereditary breast cancer gene?

Mutations to: Brca1 and brca2 is associated with the most common inheritable breast cancer. ...Read more

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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read more

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Is breast density a risk factor for breast cancer? Mammogram noted "extremely dense breasts".

Is breast density a risk factor for breast cancer? Mammogram noted "extremely dense breasts".

Yes, breast density: is a risk factor for breast cancer. The relative risk for extremely dense breasts is about 4x the relative risk of patients with almost entirely fatty breasts, and about 1.6x the RR for "average" density breasts. Find out all you need to know at http://www.breastdensity.info/ ...Read more

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Is uterine cancer genetic?

Is uterine cancer genetic?

Possible: In a sense all cancer is "genetic" in that it occurs do to changes in dna that cause cancer formation. However, if your questions is about familial/inherited cancer, then most uterine cancer is not from an inherited increased cancer risk. But some uterine cancer may be related to cancer risk genes such as brca 1/2 and other genes. Genetic counselors can help determine. ...Read more

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Can ovarian cancer and breast cancer be hereditary?

Can ovarian cancer and breast cancer be hereditary?

Yes, of course: This is one of the classic hereditary cancer syndromes. Sorry, i don't have enough characters to be allowed to give you a full asnwer here, but quoting wikipedia: http://en.Wikipedia.Org/wiki/hereditary_breast%e2%80%93ovarian_cancer_syndrome. ...Read more

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Hereditary breast cancer gene, what is it?

Hereditary breast cancer gene, what is it?

Wsh I had more space: BRCA 1 and 2 are important genes that have the purpose of repairing damaged DNA and destroying the one that can't be repaired, amongst other things. When they get mutated (or changed) in specific places, they quit working so the damaged DNA is left in there, resulting in the development of cancer. ...Read more

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What is metastatic breast carcinoma?

What is metastatic breast carcinoma?

Cancer 'elsewhere': Metastatic cancer is cancer that has spread from its organ of origin to another part of the body. For example, the most common sites of metastases for breast cancer are the lungs, liver, and bone. Most breast cancers, when caught early and treated in a timely manner, do not ever spread to other organs. ...Read more

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What is ductal incarcinoma (breast cancer )?

What is ductal incarcinoma (breast cancer )?

Breast Cancer: Learn more about intraductal carcinoma of the breast at: http://www.Intraductalcarcinoma.Net/. ...Read more

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Is cancer genetic?

Only some: Many cancers occur sporadically. Breast cancer, ovarian cancer , familial colon adenomatosis polyposis , hereditary nonpolyposis colorectal cancer , multiple endocrine neoplasia ii, multiple endocrine neoplasia i, von hippel-lindau, ; li-fraumeni syndrome can be genetically linked. ...Read more

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Dr. Barry Rosen
1,378 doctors shared insights

Breast Cancer (Definition)

Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more