Doctor insights on:
Is Crest Syndrome Fatal
Lab work: If you have some of the classic findings and an anti-centromere antibody, you're likely to receive the diagnosis. It's not always severe and sometimes the best treatment is supportive measures and observation. ...Read more
I have hashi moto andtested positive for crest syndrome. Dr. Thinks could be false positive. What should I do to know for certain false positive?
Basic doctoring: We have a joke in clinical medicine -- if a $10000 workup comes back without a clear answer, do a history and physical exam. The anti-centormere is sensitive and specific enough for crest, but it's easy for the lab to do wrong. If you do not have raynaud's, calcium chunks and hardening in the fingers, a stiff esophagus won't do its job, and odd vessel formations, stop worrying about crest. ...Read moreSee 1 more doctor answer
Read: Scleroderma is a connective tissue disease that involves changes in the skin, blood vessels, muscles, and internal organs. It is a type of autoimmune disorder, a condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001465/. ...Read more
The. R in CREST is : Raynauds which can show up as darkening if the fingers or hand due to spasm in blood vessels. But having ray aids dies not mean it is crest syndrome. Calcinosis. Esophageal dysmotility. Sclerodactyly and telangectasia are the other letters. Many causes of raymaud a are NOT associated with a known issue. Speak to your doctor about being evaluated ...Read more
Is there anything else besides lupus and crest syndrome that could lead to high centromere anitbodies on a nuclear ab screen? Could it just be a fluke
The Mighty Vitamin D: You may do better in warmer climate closer tot he equator for 2 reasons: more vitamin D and more exercise . Receiving more sunlight would naturally raise your vitamin D levels. Adequate vitamin D is essential for fibromyalgia relief, and is a powerful anti-inflammatory.More exercise, especially light walking or yoga on the beach would add to the benefit of vitamin D. ...Read more
Is crest syndrome with high centromere b antibody considered a rare disorder with rheumatologists having only a few such patients? Should i seek out a scleroderma specialty center for regular care?
Is Neurontin (gabapentin) useful for joint pain or just nerve pain? Is it safe to take if you have CREST syndrome?
CREST & Neurontin (gabapentin): Hello. Neurontin (gabapentin) is useful for joint and nerve pain. It boils down to the type of pain you have. Stabbing, burning, pins & needles, tingling, electric, numbness, etc. type symptoms usually respond to Neurontin (gabapentin). It's safe to take with CREST Syndrome. Rare for Neurontin (gabapentin) to exacerbate CREST symptoms. ...Read moreSee 1 more doctor answer
Yes and no: Crestor’s maker suggests it should be taken whole and not be crushed, chewed, or broken. There is no reason that it cannot necessarily be crushed, aside from the coating possibly masking the drug’s medicinal taste, but do be aware upon crushing the tablet, some of the coating pieces could remain, kind of how like if you crushed M&M’s, you’d see the difference between chocolate and candy coating. ...Read moreSee 1 more doctor answer
Not much: Treatment of elevated lp(a) is a bit tough. Potent statins can mitigate the risk by lowering the ldl-cholesterol level as much as possible (below 70 mg/dl), since that particle is tied to the ldl-c molecule. Estrogen therapy in women, Niacin in both sexes, and in the future, cholesterol ester transfer protein inhibitors (if they come to market) may lower lp(a) levels. ...Read more
Statin - Rosuvastati: Crestor is the brand name for rosuvastatin, one of several "statin" medications that inhibit hmg co-a reductase, the rate limiting enzyme in cholesterol synthesis. These medications increase the number of LDL receptors that bind and remove LDL particles from the circulation. Statins have been shown to significantly reduce heart attack, death from heart attack, and ischemic stroke. ...Read moreSee 1 more doctor answer
Crestor (rosuvastatin): It is generally believed that cholesterol is produced by the body at night. The first drugs in the class (statins) were recommended to be taken with the evening meal. However, the new statins such as Crestor (rosuvastatin) have in the product labeling that it can be taken any time during the day. However, if it's not a hardship, i would still recommend that you take your Crestor (rosuvastatin) with your evening meal. ...Read more
Impossible: There is no generic medication for Crestor (rosuvastatin) at this time as the medication is still under patent. The generic name for Crestor (rosuvastatin) is Rosuvastatin and you may be on that med, but it is not generic (and won't be for years). Generic statins currently available are pravastatin, simvastatin, atorvastatin, and lovastatin. All statins have the same action, but some may be better for some people. ...Read more
Can Be Taken Anytime: Some statins (pravachol, zocor, (simvastatin) mevacor) have very short half-lives (2-4 hours) and have a better effect if taken at night. This is because the medication works by decreasing cholesterol synthesis which is increased during the evening hours. Other statins (lipitor, crestor) have very long half-lives (14-18 hours) and have equal effect if taken in the morning or evening. ...Read moreSee 1 more doctor answer