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Doctor insights on: Is Aleve Bad For Your Liver

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Dr. Arnon Rubin
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Dr. Mary David
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Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Is there proof that Aleve or other naisd's can cause liver damage?

Is there proof that Aleve or other naisd's can cause liver damage?

Possible: As you imply, there is controversy over how serious the role of nsaisd and liver damage really is. The best reference I have seen is world j gastroenterol 2010 december 7; 16(45) 5651-5661. While there is some risk with all nsaids, discontinuation usually reverses problem. The presence of jaundice is a serious risk factor for liver failure. Sulindac and nimesulide have both been linked hi risk. ...Read more

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Dr. Arnon Rubin
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Is it possible that Aleve increase liver enzymes?

Is it possible that Aleve increase liver enzymes?

Famously: Naproxen is well-known to do this, and about 1 in 25 people who start taking it on a regular basis get elevated liver enzymes. Perhaps it's time to look at taking a different nsaid; if the liver enzymes remain high, it would be wise to look for a different dangerous-if-untreated cause of the elevated 'zymes. ...Read more

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Dr. Arnon Rubin
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5
Ihave very high count mitochondrial antibodies and have been diagnosed with fatty liver disease. Is it ok to take aleve for muscle pain I'm having?

Ihave very high count mitochondrial antibodies and have been diagnosed with fatty liver disease.  Is it ok to take aleve for  muscle pain I'm having?

Fatty liver disease: You should not take anything over the counter without approval from your liver disease doctor. Most likely the answer will be "It's OK" but don't take chances. ...Read more

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I am obese had baristruc surgery. Just found out I have a slightly large heart, and ^ liver enzymes. I hurt my knee can I take an Aleve w/said issues?

I am obese had baristruc surgery. Just found out I have a slightly large heart, and ^ liver enzymes. I hurt my knee can I take an Aleve w/said issues?

NSAIDs : What type of bariatric surgery did you have? Gastric bypass? Lap band? Sleeve gastrectomy? The biggest concern is taking nsaids after a gastric bypass because it can cause you to form ulcers in your gastric pouch. If you do take nsaids, you should take a proton pump inhibitor like prevacid, prilosec, etc. ...Read more

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Is taking naproxen 500 2 x plus 10/325 x 5 goingto cause liver problems? Thank you.

Is taking naproxen 500 2 x plus 10/325 x 5 goingto cause liver problems? Thank you.

Not likely: No drug interactions between Norco and naproxen. This drug may rarely cause serious (possibly fatal) liver disease. Nausea, vomiting, constipation, drowsiness lightheadedness and dizziness are common side effects. Rec.: for more information discuss with your prescribing physician. ...Read more

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Can you take naproxen 500mg then take either tylenol or aspirin for break through pain. Are this meds ok to take with elevated liver functions?

Can you take naproxen 500mg then take either tylenol or aspirin for break through pain.  Are this meds ok to take with elevated liver functions?

Safer alternatives: In light of a history of liver dysfunction, acetominophen (tylenol) should be limited. Since you are already looking for something else to help beyond naproxen, it is time to ask your medical professional for better and safer options. Some alternative treatments or "stronger" medications will actually be safer over time with less chance for liver or kidney toxicity. ...Read more

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What are the chances of getting liver or kidney failure from naproxen overdose?

What are the chances of getting liver or kidney failure from naproxen overdose?

It depends what dose: An overdose is a relative term. Otc dose is less than half of the prescription dose. However, the dose is guided by other risks also e.g. Causing ulcer or gastritis or blood thinning. The drug could certainly cause renal failure even in mild overdose, but on the other hand some people handle it better than others. Sometimes it is too late when people figure out that they actually don't tolerate it. ...Read more

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Naproxen (Definition)

Naproxen is a non-steroidal anti-inflammatory drug. It inhibits cyclooxygenase thus reducing ...Read more


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Aleve (Definition)

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Dr. Arnon Rubin
Board Certified, Internal Medicine
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