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Doctor insights on: Is Aleve Bad For Your Liver

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I was wondering are aspirin or Aleve (naproxen) bad for your liver?

I was wondering are aspirin or Aleve (naproxen) bad for your liver?

Rarely: Aleve (naproxen) is more likely to cause liver inflammation but this is a relatively uncommon side effect. ...Read more

Dr. Janice Alexander
2 Doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Is it possible that Aleve (naproxen) increase liver enzymes?

Is it possible that Aleve (naproxen) increase liver enzymes?

Famously: Naproxen is well-known to do this, and about 1 in 25 people who start taking it on a regular basis get elevated liver enzymes. Perhaps it's time to look at taking a different nsaid; if the liver enzymes remain high, it would be wise to look for a different dangerous-if-untreated cause of the elevated 'zymes. ...Read more

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Is there proof that Aleve (naproxen) or other naisd's can cause liver damage?

Is there proof that Aleve (naproxen) or other naisd's can cause liver damage?

Possible: As you imply, there is controversy over how serious the role of nsaisd and liver damage really is.
The best reference I have seen is
world j gastroenterol 2010 december 7;
16 (45) 5651-5661.
While there is some risk with all nsaids, discontinuation usually reverses problem. The presence of jaundice is a serious risk factor for liver failure. Sulindac and nimesulide have both been linked hi risk. ...Read more

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Ihave very high count mitochondrial antibodies and have been diagnosed with fatty liver disease. Is it ok to take aleve (naproxen) for muscle pain I'm having?

Ihave very high count mitochondrial antibodies and have been diagnosed with fatty liver disease. Is it ok to take aleve (naproxen) for muscle pain I'm having?

Fatty liver disease: You should not take anything over the counter without approval from your liver disease doctor.

Most likely the answer will be "It's OK" but don't take chances. ...Read more

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I am obese had baristruc surgery. Just found out I have a slightly large heart, and ^ liver enzymes. I hurt my knee can I take an Aleve (naproxen) w/said issues?

I am obese had baristruc surgery. Just found out I have a slightly large heart, and ^ liver enzymes. I hurt my knee can I take an Aleve (naproxen) w/said issues?

NSAIDs: What type of bariatric surgery did you have? Gastric bypass? Lap band? Sleeve gastrectomy? The biggest concern is taking nsaids after a gastric bypass because it can cause you to form ulcers in your gastric pouch. If you do take nsaids, you should take a proton pump inhibitor like prevacid, (lansoprazole) prilosec, etc. ...Read more

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How does the liver metabolise naproxen?

How does the liver metabolise naproxen?

Naproxen metabolism: See: http://www. Ncbi. Nlm. Nih. Gov/pubmed/16187975

Get a more detailed answer ›
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Is taking naproxen 500 2 x plus 10/325 x 5 goingto cause liver problems? Thank you.

Not likely: No drug interactions between Norco (hydrocodone and acetaminophen) and naproxen. This drug may rarely cause serious (possibly fatal) liver disease. Nausea, vomiting, constipation, drowsiness lightheadedness and dizziness are common side effects.
Rec.: for more information discuss with your prescribing physician. ...Read more

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Would taking naproxen pills for a long time damage the liver?

Would taking naproxen pills for a long time damage the liver?

Rarely: Anyone taking long term NSAIDs such naproxen needs to have periodic blood tests to screen for anemia, liver or kidney issues related to these meds. ...Read more

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What to do if I have an intermittent pain in my right subscapular area. It responds to naproxen sometimes. Liver & gs?

Uncertain where it c: It is uncertain where it is coming from. What makes it worse and what makes it better? It could be shoulder joint arthritis, shoulder tendonitis, shoulder bursitis. Your physician can help define this ...Read more

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What're the chances of liver or kidney failure from naproxen overdose?

What're the chances of liver or kidney failure from naproxen overdose?

Small, but: Very small as long as safety monitoring with cbc, liver and kidney function and urinalysis evalation at 3 month intervals, as long as checked initially at 1 week and 1 month and when any additional medications are added. ...Read more

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What are the chances of getting liver or kidney failure from naproxen overdose?

What are the chances of getting liver or kidney failure from naproxen overdose?

It depends what dose: An overdose is a relative term. Otc dose is less than half of the prescription dose. However, the dose is guided by other risks also e.g. Causing ulcer or gastritis or blood thinning. The drug could certainly cause renal failure even in mild overdose, but on the other hand some people handle it better than others. Sometimes it is too late when people figure out that they actually don't tolerate it. ...Read more

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Can you take naproxen 500mg then take either tylenol (acetaminophen) or aspirin for break through pain. Are this meds ok to take with elevated liver functions?

Can you take naproxen 500mg then take either tylenol (acetaminophen) or aspirin for break through pain. Are this meds ok to take with elevated liver functions?

Safer alternatives: In light of a history of liver dysfunction, acetominophen (tylenol) should be limited. Since you are already looking for something else to help beyond naproxen, it is time to ask your medical professional for better and safer options. Some alternative treatments or "stronger" medications will actually be safer over time with less chance for liver or kidney toxicity. ...Read more

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I have severe pain in my left abdomen as well as swelling. What should I do. I fell down the stairs last tuesday and the pain has worsened instead of getting better. I have tried Aleve as well as my prescription muscle relaxer and anti-inflammatory. I am

Hello.: Hello. I can't diagnose the cause of your pain. However, it there is significant abdominal pain and severe pain which is worsening I recommend that you seek medical attention. It would be important to rule out internal injury or internal bleeding. ...Read more

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My wife is currently having severe pinching pain in her lower right abdomen. She just took naproxen. She underwent dnc 2mths ago. Plz help, what 2 do?

Appendix: Appendicitis is a possible reason for her symptoms. If her pain is lower down, ovarian cysts or other female organ problems could be a source of her pain. Even though her d/c was two months ago, a rare infection is a possibility. Not knowing why she had the procedure, there is a possibility she may have a reoccurrence of the initial problem. I believe she needs an exam and possible tests ...Read more

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I am currently on naproxen 500mg bid for headaches. Lately I have sharp pain on lt side of abdomen below ribs. Cause? What should I do?

I am currently on naproxen 500mg bid for headaches. Lately I have sharp pain on lt side of abdomen below ribs. Cause? What should I do?

Have it evaluated: It could be several things including significant GI irritation from the naproxen. Stop the Naproxen until the cause of the pain is determined. You do not want to end up with an ulcer or GI bleed. ...Read more

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Is Alleve safe to take for someone with Non Alcoholic Fatty Liver Disease?

Yes if no cirrhosis: Aleve (naproxen) and Motrin (ibuprofen) are primarily excreted by the kidneys and not metabolized in the liver. If a patient with NAFLD is asymptomatic, has normal liver function (bilirubin) and no evidence of cirrhosis Aleve and Motrin can be taken without toxicity.
NSAIDS can occasionally elevate hepatic enzymes so it's
probably wise to check LFT's occasionally if using NSAIDS regularly. ...Read more

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My cycle started today, and I just took 4 aleve at once, is that bad? What will happen to me?

Aleve/menses: Taking 4 aleve today probably will treat your pain and discomfort today without side effects. No further med should be taken today and 24 hrs from now. Sometimes in some people bleeding/bruising can occur, emesis, diarrhea. Just observe for now. ...Read more

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Is taking 8 aleve (naproxen) at once bad?

NSAID: It may cause gastritis and if you have underlying kidney disease it may also be a problem leading deterioration in kidney function ...Read more

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Is taking 1 Aleve (naproxen) every day bad for ylu?

See details: There is always a risk of ulcers or other GI issues for the long term use of aleve (naproxen) or other nsaids. The risk of a single aleve (naproxen) tablet is relative low but always take it with a meal. ...Read more

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I'm on Plavix and have a bad headache. Can I take an Aleve?

I'm on Plavix and have a bad headache. Can I take an Aleve?

Caution: I would avoid taking non steroidal products along with plavix due to the increased risk of bleeding with the mix.
Simple tylenol may be a better choice. Should the headache become very severe, change your vision or get nausous go to the ER ...Read more

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Is it bad to take mobic (meloxicam) or aleve if you have acid reflux?

Is it bad to take mobic (meloxicam) or aleve if you have acid reflux?

Taking NSAIDs: Generallyn it is pretty safe to take NSAIDs if you have reflux. I would take them with food. If you have known ulcer disease, it is wise to limit the NSAIDs or take them with a protective drug that reinforces the liking of the stomach. Avoid drinking a lot when you are being treated for ulcer disease. Good luck and feel better. ...Read more

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Took 2 Aleve (naproxen) at 11am, and one at 10pm same day, when is the next safe time I can take, and is taking 2 at same time bad?

About 12 hours...: Should take approximately 12 hours apart. Aleve is naproxen 220 mg. It is fine to take 2 Aleve at a time as long as you are hydrated and do not have underlying kidney disease or take large doses of diuretics. ...Read more

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Is it bad to take Aleve (naproxen) everyday for headaches?

Symptoms vs Cure: Not in general. But wouldn't it be a better approach to find out the cause of the headaches and treat that rather than just treating the symptoms of the headache? ...Read more

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Magic mushrooms and aleve, (naproxen) is it bad to mix the 2?

Magic mushrooms and aleve, (naproxen) is it bad to mix the 2?

Forget the naproxen: The danger is in the 'magic mushrooms.' there is nothing magic about them, and the reality is that you have really no way to know what you are getting. If pure psilocybin/psilocin, there are still 'bad trips' from them. But they may really by pcp or amphetamine-based drugs like ecstasy, which can have very serious problems. At 46 you aren't a kid - high pulse with these drugs not good for heart. ...Read more

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Aleve (naproxen) for headaches. Is it bad to take everyday? Wat else could I try?

Aleve (naproxen) for headaches. Is it bad to take everyday? Wat else could I try?

Not recommended: Daily. Patients who use acute medications excessively to alleviate migraine are at risk for developing analgesic rebound headache and drug-induced headache. These patients may also use medications provided by family and friends and it is not unusual for a migraine patient to use both prescription and nonprescription analgesics at the same time.
Rec. See headache and orofacial pain specialist. ...Read more

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What can I do if my friends daughter took 25 Aleve (naproxen) pills is that bad she's 14 weighs 150?

Massive overdose: That is a massive overdose and she needs psychiatric evaluation and lab tests to make sure she has not caused major damage to her kidneys. Go to the er now. ...Read more

Naproxen (Definition)

Naproxen is a non-steroidal anti-inflammatory drug. It inhibits cyclooxygenase thus reducing ...Read more


Dr. Heidi Fowler
888 Doctors shared insights

Aleve (Definition)

Aleve ...Read more