Doctor insights on:
Is A Twisty Loopy Colon Hereditary
Genes: Most colon cancers are not inherited. However, there is a subset which is associated with inherited genetic abnormalities such as hereditary polyposis a this hereditary non polyposis gene (hnpp). There are also syndromes that make you susceptible to a variety of different cancers including colon cancer such as lynch syndrome. ...Read moreSee 2 more doctor answers
I have gastroparesis and pseudo-obstructive disorder. I had >3.5' of colon removed and still have problems. My kids seem to have inherited it; help?
Doctors can help: An adult with such problems can be cared for by his primary care doctor or his G.I. Specialist. Sometimes various medications, foods, etc..., are tried, with different meds showing some level of effectiveness at different times in a patient's life. Kids can see their pediatrician and a pedi GI doctor for help. With chronic problems, be sure to always have very good medical insurance. ...Read more
Some colon cancers: Are hereditary. Vast majority are not. The two common hereditary forms of colon cancer are familial adneomatous polys and lynch syndrome. Let me reiterate that hereditary colon cancers are a minority. See this site for more info. http://www.mskcc.org/cancer-care/hereditary-genetics/inherited-risk-colorectal. ...Read more
Can be: Most colon cancers relate more to lifestyle than inheritance but some patients do have an inherited predisposition, be it in the setting of multiple polyps (like fap or myh) or not (lynch syndrome). Families with this have early onset colon cancer and other cancers as well. Talk to your doc about this to see if you need to visit a specialist in inherited malignancies. Remember to live healthy. ...Read more
My uncle has cancer of the of the colon due to poor diet. We have no cancer history in the family but i've been wondering if this is hereditary?
Unlikely genetic: Just one member of the family is not enough to call it familial cancer , 75 % of colon cancers has no family history , so don't worry , you are 21 and if no symptoms , 20 years from now go for regular screening colonoscopy , you will be fine. Yes diet plays a roll but unlikely it is the cause of cancer , develop good dietary habits, eat lots of veggies, fruits, less re meat , will be fine. ...Read more
Not in 400 character: Many genes are linked with an increased risk of colon cancer (and others), so those with a family history of colon, uterine and other cancers are at increased risk as they may inherit these genes from their parents. Genetic testing can pinpoint some of these genes and thus indicate whether you are at increased risk, thus allowing earlier detection/prevention/treatment so get checked if this appies. ...Read moreSee 1 more doctor answer
5-10% of colon CA's: ...include: familial adenomatous polyposis (FAP) and Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC). In addition, some rare conditions – including attenuated familial adenomatous polyposis (AFAP) and MUTYH-associated polyposis (MAP). Read: https://www.mskcc.org/cancer-care/risk-assessment-screening/hereditary-genetics/genetic-counseling/inherited-risk-colorectal ...Read more
If a person in their mid 30's were to get colon cancer would it almost always be due to a hereditary form of cancer compared to sporadic?
Maybe: Some hereditary factors increase colon cancer risks such as some types of colitis (ulcerative colitis, crohn's disease), familial polyposis, hnpcc, lynch syndrome, etc. But younger people can get spontaneous colon cancers too. Get a referral to a gastroenterologist as indicated. Most colon cancer occurs after age 50, and reported 8-10 people per 100, 000 get colon cancer under age 50. ...Read moreSee 1 more doctor answer
Several.: The types of colorectal cancers you refer to include hnpcc (hereditary nonpolyposis colorectal cancer) and fap (familial adenomatous polyposis). However, each of these can also arise form a new mutation with no family history. Garden variety colorectal cancer also has some heritability, though far less than those noted above. ...Read moreSee 1 more doctor answer
Family risk: You will want to get colonoscopy from time to time starting soon. Your family members may also be checked for genetic problems such as HPNCC and familial polyposis; if they are affected, you may be checked as well. Getting 'scoped frequently greatly diminishes your risk of dying of this illness. ...Read more
If theres hereditary predisposition of colon cancer how often should a person do colonoscopy and wha are the risk factors? And What is polyposis test?
Colon CA/screening: ACS screening for families that have a strong history. There are families that have predisposition to develop color and rectal CA. They say screening should start 10 yrs prior to the family members Dx. Say mom Dx at 40, screening would start at 30 in her family. Once you've had the first scope re can be made on the frequency, every 3 to 5 yrs depending on number of members Dx. ...Read more
Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca. ...Read more
For what reason colon part is usually prone to cancer in hnpcc (hereditary hereditary nonpolyposis colorectal cancer)?
Is carcinoid syndrome hereditary? My died at age 42 & i've already got bad stomach problems & colon polyps.
It can be hereditary: 4% of carcinoid tumors are hereditary. The most common inherited disorder involving carcinoids is men syndrome type i. Other neuroendocrine tumors are usually present in this syndrome, though. Familial carcinoids are more erratic in heritability. There is no formal test for suspected familial carcinoid. Symptoms of carcinoid syndrome include chronic flushing and diarrhea. ...Read more
My dad died at 42 with carcinoid syndrome. Started in colon & intestine then to liver. I have already had colon polyps removed. Is this hereditary?
Mother has breast cancer at 53, her father had colon at 87, her paternal uncle had aml at 65 and her paternal cousin aml at 50. Hereditary?
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