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Doctor insights on: Is A Ca 125 Level Of 94 Bad

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Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?

Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?

Likely, no: CA 125 is not recommended as a screening tool for ovarian cancer when used in risk-based stratification. Meaning, assuming that your mom or sister didn't get diagnosed with ovarian cancer. Normal for women with endometriosis to have elevated CA-125. It sounds like your doctor has done Ultrasound to evaluate ovaries as well. Your MD knows your history and risk, likely this CA-125 level is normal ...Read more

Dr. Corey Clay
128 Doctors shared insights

Ca125 (Definition)

Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more


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Is a ca 125 level of 18 normal for a 38 year old female? Range is <36.

Yes: Ca 125 is not a good screening test. See this site for more info.
http://www. Medicinenet. Com/ca_125/article. Htm. ...Read more

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How concerned should I be if my ca125 level was not ordered this year?

How concerned should I be if my ca125 level was not ordered this year?

None to minimal: If the ca-125 was going to be used simply as another blood test for example in a yearly physical, you should not be terribly concerned at all. My answer is different however, if you have a history of a disease such as ovarian cancer and that it should be checked. I also might order it if you have a strong family history of ovarian cancer for example. If not you should not be concerned. ...Read more

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What does ca 125 level 600 mean?

High: It's quite elevated, why was it done? Your doc needs to discuss this results with you in the context in which it was ordered. ...Read more

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Ca125 level is a marker for which tumor?

Ca125 level is a marker for which tumor?

Ovarian: It is neither sensitive nor specific for screening. However, its recurrence after removal of a tumor that produces it suggests recurrence. ...Read more

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I had the ca-125 test done and it came back with a level 25. Should I be concerned?

Yes and No: Ca-125 is a test for follow-up after diagnosis and with the treatment of ovarian cancer. It is elevated in many other diseases. The test should not be used for a fishing expedition because it would be misleading and concerning for a patient like you. Why was the test done in the first place? Do you have cancer? In any case a 25 level could be normal? What was the normal range. In the lab? ...Read more

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Does an elevated ca 125 level always indicate that ovarian cancer is present?

Does an elevated ca 125 level always indicate that ovarian cancer is present?

No: Ca-125 may also be elevated in other cancers (i.e. Endometrial, fallopian tube, lung, breast and gastrointestinal cancers.) it can also be elevated with endometriosis or any inflammatory condition in the abdominal area. ...Read more

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Mildly complex ovarian cyst 4.5cm in postmenausal woman. Ca125 is 15. Having surgery tomorrow so worried! Can it be something bad? Help!

Mildly complex ovarian cyst 4.5cm in postmenausal woman. Ca125 is 15. Having surgery tomorrow so worried! Can it be something bad? Help!

Talk to doctor: Many women will develop cysts in their life. The vast majority are benign, but some do develop into cancer. Having a ca 125 that low is a good sign, but no one can tell until the cyst is examined by a pathologist after surgery. After surgery, your doctor will be able to give you more detailed answers. ...Read more

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My ca125 levels are slightly elevated and there is a solid mass on my ovary, should I be concerened that it is ovarian cancer?

Depends: Ask your gyn. A solid mass is concerning, but your age, menopausal status, and the ultrasound characteristics are important as well. Elevated ca-125 suggests ovarian cancer, but may be somewhat elevated in many benign conditions, as well, including endometriosis. All of this needs a discussion with your gyn and a possible referral to a gyn oncologist - who are the real experts in this area. ...Read more

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2 ovarian cyst, one 8 CM and the other 6cm. Had vus done, low level echos. Going back in 2 months for review. Ca-125 in normal limits. Concered?

2 ovarian cyst, one 8 CM and the other 6cm. Had vus done, low level echos. Going back in 2 months for review. Ca-125 in normal limits. Concered?

Low degree of concer: Most common cause of such benign cysts are functional cysts that are very common in reproductive age females. Unless, presenting with symptoms (pain, nausea, vomiting, fever etc), your physician may opt to follow them with a repeat us in 3-6 months.
Unless you have strong family hx of cancer, or personal hx of cancer, there is a low level of suspicion for ovarian cancer. ...Read more

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When your gyn checks you for an ovarian cyst and then asks you to take a blood test for ca-125. Is that a bad sign?

When your gyn checks you for an ovarian cyst and then asks you to take a blood test for ca-125. Is that a bad sign?

CA 125 - Why check?: Cancer antigen 125 (ca-125) is not a screening test for ovarian cancer. It is an adjunctive test for measuring tumor response (ie, a tumor marker) for pts w/ known ovarian cancer. It isn't perfect even when we know someone has ovarian cancer. In the appropriate clinical setting -- eg an abnormal ovary on imaging it might help determine if a mass is benign or malignant, but again is not perfect. ...Read more

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CA 125 level in a 70yr woman who had hysterectomy with removal of ovaries+Fallopian tubes=341U/ml. Possibillity? Waiting for results of pelvic+abd u/s.

CA 125 level in a 70yr woman who had hysterectomy with removal of ovaries+Fallopian tubes=341U/ml. Possibillity? Waiting for results of pelvic+abd u/s.

Waiting is hard: Although it's hard to wait, your doctor is evaluating you for possible abdominal or pelvic cancers which can show up even after removal of the uterus, tubes, and ovaries. They may also recommend a CT (cat scan) or PET scan If the u/s isn't helpful. Best wishes for good results! ...Read more

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7 CM ovarian cyst, ca-125 levels elevated (48), roma score & all blood tests good. Previously had nasopharyngeal cancer. Recurrence or endometrioma?

Likely endometrioma: At your age, ovarian cancer would be exceedingly rare. Ca-125 levels can be elevated in young women for a variety of reasons that have nothing to do with cancer. Nasopharyngeal cancer and ovarian have no relation to each other. Your doctor should tell you what features or characteristics the ovarian cyst has, this will tell you what kind of cyst it is. Good luck! ...Read more

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My ca 125 range is 900 fluid in stomach & cyst in ovary. Biopsy done twice but doc r NT able 2 find why ca125 levels r high. Cancer not diagnosed yt?

My ca 125 range is 900 fluid in stomach & cyst in ovary. Biopsy done twice but doc r NT able 2 find why ca125 levels r high. Cancer not diagnosed yt?

Yipes!: Please see a qualified doctor soon! You need to be evaluated by a specialist (i would suggest a referral to gyn-oncologist). Your levels are worrisome, but, yes, there are possibly some non- cancer reasons for this. ...Read more

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Where does ca125 originate?

In the peritoneal li: It arises from the irritation or growth of peritoneal lining cells. These cells also cover the ovaries. So ca 125 is often used as a test to screening for ovarian cancer. But it often raised in any conditions causing intra -abdominal irritation like in peritonitis. ...Read more

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What is the definition or description of: ca125?

CA125 Definition: Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast et al. In 1983. ...Read more

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What is the ca-125 test?

CA-125: Cancer antigen 125 (ca-125) is a protein found on the surface of many ovarian cancer cells. It also can be found in other cancers and in small amounts in normal tissue. A ca-125 test measures the amount of this protein in the blood and can be used as a tumor marker. ...Read more

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What causes my ca 125 to go up?

Many causes: It is commonly elevated in ovarian cancer. But it can go up from any reason which causes irritation of the peritoneal lining of your abdomen which includes some benign conditions too. It depends on the level and also if it is going up steadily or staying elevated but stable and not increasing. Your gynecologist can help you to sort it out. ...Read more

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What is the significance of ca-125?

Ovarian Cancer: It is a tumor marker for ovarian, endometrium, fallopian tube, lung, breast and gastrointestinal tract cancers. It is commonly used to follow ovarian cancer in response to therapeutic treatments and can be positive in nearly 80% of cases. It is not specific to cancer, however, and can be elevated in benign abdominal problems too such as endometriosis. ...Read more

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Is 80.04 result of my ca 125 can be cured?

Cannot tell: More information is needed to recommend possibility of cure. Please re-ask the question with what diagnosis included and any previous treatment. ...Read more