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Doctor insights on: Is 400 Mg Of Diphenhydramine To Help Sleep To Much

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Dr. Heidi Fowler
5,051 Doctors shared insights

Sleep (Definition)

Sleep is a topic that involves concepts such as how long it takes to fall asleep, how many times one wakes up at night, how many hours one sleeps at night, sleep stages, ...Read more


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Is 400 mg of diphenhydramine to help sleep to much?

Is 400 mg of diphenhydramine to help sleep to much?

Definitely: 400 mg is the maximum daily dose for severe allergic reactions, in a hospital setting. For sleep, 50 mg should be the maximum, to avoid both unpleasant and even potentially life-threatening adverse events. Central nervous system effects are particularly significant. Even for "benign" meds, packaging dose limits are not suggestions; they balance efficacy with safety and should be followed. ...Read more

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Doctor suggested Benadryl (diphenhydramine) to help sleep. Can I take melatonin with it? I have 5mg tablets.

Doctor suggested Benadryl (diphenhydramine) to help sleep. Can I take melatonin with it? I have 5mg tablets.

Yes, in fact yes,: In fact, take melatonin nightly, use Benadryl (diphenhydramine) all if need it, and if taking Benadryl (diphenhydramine) nightly, after a while on melatonin, may be able to stop benadryl (diphenhydramine). ...Read more

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Is taking 100mg of diphenhydramine to sleep at night safe?

Is taking 100mg of diphenhydramine to sleep at night safe?

Exceeds recomended: This is twice the recommended dose as a sleep aid. The general therapuetic dose is up to 1mg/kg so you might tolerate this dose ok if you weigh at or above 220 lb. At this level caution is advised. You would likely remai groggy for 4-8 hours under the effects of the medication. Operation of a motor vehicle or tools would be unwise. ...Read more

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Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

No: I am not sure what l-theanine is. However, the only dietary supplements/herbals I know of which should be avoided when taking Diphenhydramine are valerian, st. John's wort, kava kava, and gotu kola; as the combination may enhance CNS depression. I am doubtful that whatever l-theanine is will compound any sedative effects you may experience with Diphenhydramine alone. ...Read more

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Is it bad to take Benadryl (diphenhydramine) to sleep?

Is it bad to take Benadryl (diphenhydramine) to sleep?

Sleep: I wouldn't recommend taking it as a long term sleep aid. Melatonin may be a better option for you. ...Read more

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What amount Benadryl (diphenhydramine) will make me sleep?

What amount Benadryl (diphenhydramine) will make me sleep?

Depending on: Your weight 25-50 mg at bedtime should be the appropriate dose to help you sleep ...Read more

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Does Benadryl (diphenhydramine) interfere with proper sleep?

Yes it is possible.: Though rare, there have been reported cases of insomnia (sleep problems), restlessness and agitation with use of diphenhyramine (benadryl).Common side effects include, constipation/diarrhea/ drowsy/headache report these to your doctor as soon as possible, confused, agitated, nervous, irregular or fast heartbeat, tremor, trouble passing urine. Please see doctor for proper diagnosis
and care. ...Read more

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How safe and effective is 50mg of Benadryl (diphenhydramine) for sleep?  

How safe and effective is 50mg of Benadryl (diphenhydramine) for sleep?  

Very: Diphenhydramine is the active ingredient in bendryl, and is also used on multiple other bedtime over the counter preparations to cause drowsiness - i.e., tylenol (acetaminophen) pm, simply sleep, etc. ...Read more

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How long in advance do you take Benadryl (diphenhydramine) for sleep help?

It depends: Most oral medicines start working 45 to 60 minutes after you take it. ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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Can you take up to six benadryl (diphenhydramine)? What puts you to sleep faster?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
Can you take up to six benadryl (diphenhydramine)? What puts you to sleep faster?

Benadryl (diphenhydramine): Not advised, but can try the sleep hygiene techniques (detailed in my previous answers) at same time. ...Read more

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Giving Benadryl (diphenhydramine) to a child to make them sleep, what systems shuting down w/overdose?

Wrong: There is nothing to compare with normal child's sleep. It is the most tranquil form of sleep. Find out why your child cannot sleep for it is definitely abnormal and indicates an irritable nervous system. ...Read more

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I took a Benadryl (diphenhydramine) and fell a sleep. It must of wore off because I woke up an hour and a half later, can I take another one?

Read drug label: Please take medications as directed. Instructions are usually printed on the ingredient label. You can always take another one but not until specified amount of time has elapsed. ...Read more

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How long does diphenhydramine stay in your system? I took 100mg before sleep, but 12 hours later, I'm still drowsy. The more dosage, the longer?

Takes a while: It sounds like it is still in your system. The half life varies quite a bit from person to person although some sources will describe a half life of around seven hours. That means that seven hours later you can still have half of the medicine in your body. As you can see, you are probably going to need more time to clear it. Stay safe! ...Read more

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I was taking diphenhydramine for sleep nightly for months but I don't feel good the next day, now taking doxylamine, what's the difference in the two?

Doxylamine: Doxylamine is a member of the ethanolamine class of antihistamines and has anti-allergy power superior to almost every other antihistamine on the market, with the exception of Diphenhydramine (benadryl); it is also the most effective over-the-counter sedative available in the United States and is more sedating than some prescription hypnotics. En.Wikipedia. Org/wiki/doxylamine. ...Read more

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My Dr felt presc sleep meds weren't the choice for me. So I've been taking 100mg diphenhydramine/nightly for 3 yrs. Should I continue to take the OTC?

My Dr felt presc sleep meds weren't the choice for me. So I've been taking 100mg diphenhydramine/nightly for 3 yrs. Should I continue to take the OTC?

Better Sleep Hygiene: Try better sleep habits before relying on meds. Maintain regular sleep schedule, do not force sleep, avoid caffeine beverages after lunch, avoid alcohol near bedtime, avoid smoking or other nicotine products, adjust bedroom environment to decrease stimuli (reduce ambient light, turn off television), avoid prolonged use of light-emitting screens before bedtime (laptops, tablets), reduce stress. ...Read more

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Would a diphenhydramine overdose make you sleep?

Would a diphenhydramine overdose make you sleep?

Maybe: Diphenhydramine is in over the counter sleep meds. It is also known as benadryl, (diphenhydramine) a common antihistamine with a side effect of drowsiness. Sometimes there is an opposite effect, especially with young childen, elderly, or if too much is taken, and you don't sleep. ...Read more

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What can happen to me if I take 8 pills to sleep pills are called diphenhydramine

What can happen to me if I take 8 pills to sleep pills are called diphenhydramine

As: As with any medication, taking amounts over the recommended does can lead to serious side effects. Diphenhydramine overdose can cause the following problems.

Agitation
blurred vision
coma
confusion
convulsions
delirium
diarrhea
drowsiness
dry cotton-like mouth
flushing on the face and skin
inability to urinate
incoherence (not understandable)
lack of sweat
low grade fever
movement problems
nausea
rapid heart rate
stomach pain
unsteadiness

the most concerning potential side effect is decrease in respiratory effort or heart beat irregularities that, rarely, could lead to death. ...Read more

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Help, how much Benadryl (diphenhydramine) could I take to aid sleep?

Benadryl (diphenhydramine): Depends on your tolerance & if taking other medications. Lowest dose is 25 mg. & can go to 50 mg. Unless otherwise stated by your doctor. ...Read more

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I drink 1 serving of alcohol and 1 Benadryl (diphenhydramine) to sleep, is this deadly?

I drink 1 serving of alcohol and 1 Benadryl (diphenhydramine) to sleep, is this deadly?

Risky: To mix a clearly contraindicated substance with alcohol (both causing CNS depression) is very risky. Not necessarily lethal each time you try, but to take that risk is reckless. Call 911 if you feel suicidal. Consult your dr, and please do not mix meds with alcohol. Best wishes. ...Read more

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Scientists have discovered any OTC sleep aids that have something other than diphenhydramine?

Scientists have discovered any OTC sleep aids that have something other than diphenhydramine?

Yes: Melatonin is an over the counter substance that many people take to aid sleep. It is available in many places where herbs or supplements are sold.
Also, GABA is used by many for aiding sleep. It is also available over the counter. ...Read more

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Took 4 Benadryl (diphenhydramine) pills will that help me sleep fast?

Benadryl (diphenhydramine): What milligram dose is each? . I would not recommend more than 50 mg. At 1 time. ...Read more

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I take 4 benadryl (diphenhydramine) to sleep and im 16 will it harm me?

I take 4 benadryl (diphenhydramine) to sleep and im 16 will it harm me?

Yes: First, you are still a minor, an adult should be overlooking your drug intake. Second, you exceeded the recommended amount of benadryl (diphenhydramine) for a single dose, 50 mg max, that's 2 tabs, if that's not working, it means you developed tolerance to the drug, and you may need more to induce sleep, hence the need to look for something else. See your doctor for evaluation of your insomnia, good luck ...Read more

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I'm interested to know what happens if I take 6 diphenhydramine hci 25mg sleeping pills?

Very sleepy: That would be a high dose of antihistamine there. You would probably get very sleepy although you might turn delirious! I wonder why you are interested in the specific effects of taking so many pills? I would talk with someone a out what you are going through like a primary care doctor or even a psychiatrist. Stay safe! ...Read more

Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more