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Doctor insights on: Irregular Antibody Screening Test

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Dr. Ira Friedlander
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Screening (Definition)

Examples are: colonoscopy for colon polyp or cancer; mammograms for breast lesions or cancer; psa a blood test that could indicate enlargement of cancerous prostate tissue; blood sugar or hemoglobin a! c for diabetes. Many think that scanning the whole body will pick up a cancer--in all likelihood, it will not. There also is no good blood test, yet, ...Read more


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Can an HIV antibody screening test be positive but the western blot negative?

Can an HIV antibody screening test be positive but the western blot negative?

Yes: There are 2 reasons for this kind of result: (1) a false positive, or (2) early infection before seroconversion. In someone at low risk for HIV without symptoms, another negative WB in 1 month means there's no infection. In someone at risk or with symptoms of acute infection, a viral load can be helpful. The new 4th generation antigen/antibody tests will eliminate this problem. ...Read more

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What is the accuracy of HIV 1 & HIV 2 antibody screening test's result after 6 weeks from possible exposure? Thank you :)

What is the accuracy of HIV 1 & HIV 2 antibody screening test's result after 6 weeks from possible exposure? Thank you :)

Exposure: If positive the testing is accurate. The natural history of the disease can be that many people will not be positive up to 12 weeks after the exposure and some even 6 months. ...Read more

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CMIA 4th gen antibody screening test (not antigen) for hiv 1 & 2 @50 days is 0.15 non reactive. Is antibody screening without antigen accurate @7thweek?

CMIA 4th gen antibody screening test (not antigen) for hiv 1 & 2 @50 days is 0.15 non reactive. Is antibody screening without antigen accurate @7thweek?

Conclusive at 6+ wk: Official advice by many agencies is that stand-alone HIV antibody tests are not conclusive until 3 months. However, with the modern tests in current use, including the test you had, the results actually are conclusive any time 6 or more weeks after exposure. Feel free to have another test at 3 months if another negative result will help you get beyond your fears. But I really isn't necessary. ...Read more

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Which of these 3 hep c antibody screening tests (methodology)is the most accurate: Architect Anti-HCV, Advia Centauer HCV or Roche Eclia?

Which of these 3 hep c antibody screening tests (methodology)is the most accurate: Architect Anti-HCV, Advia Centauer HCV or Roche Eclia?

About equal: All three methods are FDA approved and about equally accurate. If you have concern about active Hep C infection, get a Hep C nucleic acid test.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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Please advise whether or not is there any test for general screening of auto antibodies, and if any such test exist, what is its name? Thank you.

ANA screening: That's the name of the test usually performed to check for auto- immune disorder, but you rather need a good internist to put the picture together and come up with a working diagnosis, auto-immune diseases are myriad of conditions, so you need a working diagnosis for a proper treatment plan, good luck ...Read more

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I got HIV 1/2 antibody screening combo (cmia) test 75 days in india after exposure but it came out non reactive, is it confirmatory?

I got HIV 1/2 antibody screening combo (cmia) test 75 days in india after exposure but it came out non reactive, is it confirmatory?

You're good: Love safely from now on. Barrier protection until you are finally with that one special person with whom you'll remain true for the rest of your lives. ...Read more

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I just had an HIV 1/2 eia antibody screen w/ reflexes. Can you explain how this test works? Are there any better tests?

I just had an HIV 1/2 eia antibody screen w/ reflexes. Can you explain how this test works? Are there any better tests?

Viral Testing: To test for many infections we look for antibodies (your body's reaction to something new or foreign). In the case of HIV infection these antibodies can take three to six months to be positive on a test. This old fashioned test is a reliable and common screening tool. But, it is not the best test if one is possibly exposed. We now send HIV genetic tests which can be positive by day 21 post expos. ...Read more

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Recently I took a HIV DNA PCR test and results were detected and reference range not detected, my HIV antibody screen test came back neg I am worried?

Recently I took a HIV DNA PCR test and results were detected and reference range not detected, my HIV antibody screen test came back neg I am worried?

Recent exposure?: Follow up testing is required. Pcr tests have a false positive rate of 3-10%. If you had a recent exposure, it is possible that repeat testing will show antibody to become positive and there is a true HIV infection. If it does not, it is likely a false positive. ...Read more

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Can you have a negative hep c antibody screen blood test but a positive viral load test?

Can you have a negative hep c antibody screen blood test but a positive viral load test?

Possible: It is possible, though not common, to have the results you described. It would be prudent to consult an infectious disease specialist as hepatitis C is now curable in most cases. ...Read more

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I've had positive HIV screening test> im scared can anyone help?

I've had positive HIV screening test> im scared can anyone help?

Talk to an expert: There are a number of tests to find out whether a person is infected with hiv. Tests include: HIV antibody; p24 antigen; pcr. Once diagnosed with the virus, CD4 and viral load test is done. If you indeed had a "screening test, " there is a chance that the result was a "false positive." confirmatory testing may be necessary. If it is positive-contact a professional counselor for emotional support. ...Read more

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I'm 62yo/fem. My sister had died of ovarian ca in 1987. should I get screening tests for myself? Which ones and how often?

I'm 62yo/fem. My sister had died of ovarian ca in 1987. should I get screening tests for myself? Which ones and how often?

Ovarian cancer: Early ovarian cancer can be difficult to diagnose so when there is concern for the possibility of the diagnosis eg. Due to family history, it is wise to see a gynecologist for an examination and follow up regularly. ...Read more

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Do I need to have down's screening tests?

Do I need to have down's screening tests?

Screening can help: There is no requirement for a patient to have an invasive diagnostic test like amniocentesis to determine if a fetus has trisomy 21. However, most OB providers offer the screening test to pregnant women. Both should be accompanied by counseling so that couples can discuss them and the pregnant woman can decide what testing, if any, to undergo. ...Read more

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How should I prepare for a drug and alcohol screening/test coming up soon?

How should I prepare for a drug and alcohol screening/test coming up soon?

Depends: I assume you are using drugs since you asked this question. Stop using. Depending on what test (s) they are using, and what drugs you are using, most drugs and their metabolites are out of the body in as little as 3 days. Some drugs, particularly marijuana, may stick around in fat cells for weeks or even a few months. There is no way to flush drugs out of the body, and masking it doesn't work. ...Read more

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Does a negative westernblot for HIV1&2 (as a screening test) @ 16weeks post exposure rule out hiv1&2 100%? Do I need repeat test at 6 months? Thanks!

Does a negative westernblot for HIV1&2 (as a screening test) @ 16weeks post exposure rule out hiv1&2 100%? Do I need repeat test at 6 months? Thanks!

Wrong test, too long: The HIV Western blot test is not intended for screening and could miss some infections. You need a 4th generation (duo, antigen-antibody) test, which is conclusive any time 4 weeks or more after exposure; or a 3rd gen antibody test at least 8 weeks after exposure. Nobody needs testing as long as 6 months; even 3 month is longer than needed with modern tests. Discuss with an NHS GUM clinic. ...Read more

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Hello dr I did a screening test for safety of baby the test was negative but they writ that it will have a risk 1/25 that baby has smith-lemli-optiz?

Hello dr I did a screening test for safety of baby the test was negative but they writ that it will have a risk 1/25 that baby has smith-lemli-optiz?

Complex issue: If a woman is tested with an increased risk for Smith Lemli Opitz syndrome a consultation with a Medical Geneticist may help to better understand the nature of the disease. ...Read more

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Where can I find a reliable screening test for dementia?

Where can I find a reliable screening test for dementia?

See your doctor: The screening tests are not foolproof and need an expert review by someone who sees a lot of dementia...This comes from a dementia expert....So see your family doctor or see a gerontologist, neurologist or geriatric psychiatrist for a more expert opinion. ...Read more

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I took two puffs of marijuana 10 days ago and have never smoked before is that detectable on any screening test?

I took two puffs of marijuana 10 days ago and have never smoked before is that detectable on any screening test?

Very unlikely: Smoking such a small amount will only show up on a blood test for a few hours and on a urine test for a few days at most. A marijuana hair test may detect marijuana use for months but it is unlikely it would be positive with such a tiny amount ingested. ...Read more

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If I store my urine in a plastic sealed bottle and then heat to 90-100 F after 4 days will it pass scrutiny at a urine screening test.

If I store my urine in a plastic sealed bottle and then heat to 90-100 F after 4 days will it pass scrutiny at a urine screening test.

Honesty = best med: Probably not. Why do you want to do that? Why would you have to do that? If they accept an unmonitored collection, that is poor practice on their part. Chain of custody required: samples have to be observed, collected fresh & at body temperature warm to the touch. If this is a prescribed drug by your doctor, report it, so when the test comes back hot, they won't be surprised and they may OK it. ...Read more

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Is there a mental screening test type?

Is there a mental screening test type?

There are many: Many screening tools are available to assess mental health. Survey tests help identify dementia, bipolar disease, attention deficit disorders and others. Generally these are used when there is a worry about a particular problem, but there is good evidence that all adults should be screened for unrecognized depression. For more info on proven screening tests, check out the Prevention Checklist app. ...Read more

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Where can I find the most accurate screening tests?

Excellent question: All tests have some false positive and some false negative results, but you are right - some are better than others. The ones that are recommended by reliable sources are the best that we have. For a complete list of recommended screening tests by age, gender, and risk factor, look at the prevention checklist 2013 app. ...Read more

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What screening tests do newborns get?

What screening tests do newborns get?

Blood and hearing: Around 24 hours old babies should have blood drawn for a newborn screen and bilirubin. The newborn screen is a test that looks for genetic and metabolic diseases (the number of diseases tested varies by state). The results usually come back in 3 weeks. The bilirubin will come back in a few hours and is a measure of jaundice in the baby. Newborns also get a hearing test before hospital discharge. ...Read more

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How to pass an etg alcohol screening test?

How to pass an etg alcohol screening test?

Stop taking alcohol: For at least a week before the test. Do not even use alcohol sanitizer gels. ...Read more

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What's a urine cannabinoids screening test?

What's a urine cannabinoids screening test?

Drug test: This is a laboratory test which analyzes the concentration of marijuana products in the urine. Some consider this an invasion of privacy, but some industries require this as a screen for employment. This falls under the political issue of whether these substances are a serious problem or not. ...Read more

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Is it necessary to do prenatal screening tests?

Is it necessary to do prenatal screening tests?

Maybe not: Prenatal testing is usually for the parents, peace of mind and intervention. There are a growing number of conditions that intervention can improve outcomes. More often parents are challenged with the? Do I continue this preg? If you understand the risks and you know you would not terminate the preg, no matter what, you do not have to test. ...Read more

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What are the common screening tests for the diagnosis of cancers?

What are the common screening tests for the diagnosis of cancers?

Many: It depends on your age and gender. At age 40 women should get pap tests for cervical cancer and consider mammograms for breast cancer. There are no proven routine cancer screening tests for men at that age. Sometimes other tests are recommended if high risk. For a complete list of proven screening tests, vaccines and other ways to stay healthy, check out the Prevention Checklist iPhone/iPad app. ...Read more

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What are the most accurate psychiatric illness screening tests available?

Psychiatric illness: The most important diagnostic tool is face to face clinical interview with a psychiatrist, you can get second or third opinions.
Different scales for depression, anxiety, bipolar, psychosis can be used.
Also, tests like mmpi, mcmi help differentiate axis 1 and axis 2 with certain validity levels. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more